Pathway Component Details
| Name: | Furin |
| Definition: | Enzyme that cleaves Pro-endothelin to produce big endothelin |
| Category ID: | P00575 |
| Synonyms: | |
| Upstream: | |
| Downstream: |
Pro endothelin 1, 2, 3, and 4
(Pro ET1-4)
Big endothelin 1, 2, 3, and 4 (Big ET1-4) |
| Number Families/Subfamilies: | 4 |
| Number of Associated Sequences: | 17 |
| GO Molecular Function: |
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| GO Biological Process: |
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| GO Cellular Component: |
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| PANTHER protein class: |
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| References: | Medline:9883741 |
Sequence Association
| Panther Subfamily | Associated Sequence | Definition | Confidence Code | Evidence |
| PTHR42884:SF1 | A0A8I3N1T9 | Furin, paired basic amino acid cleaving enzyme | ISS | PubMed:10956649 |
| A0A8I3N1T9 | Furin, paired basic amino acid cleaving enzyme | ISS | PubMed:11861638 | |
| A0A8I3N1T9 | Furin, paired basic amino acid cleaving enzyme | ISS | PubMed:95328031 | |
| A0A8V0X4D8 | Furin, paired basic amino acid cleaving enzyme | ISS | PubMed:10956649 | |
| B0JYR0 | Furin (Paired basic amino acid cleaving enzyme) | ISS | PubMed:10956649 | |
| B0JYR0 | Furin (Paired basic amino acid cleaving enzyme) | ISS | PubMed:11861638 | |
| B0JYR0 | Furin (Paired basic amino acid cleaving enzyme) | ISS | PubMed:95328031 | |
| F7CEB1 | Furin | ISS | PubMed:10956649 | |
| F7CEB1 | Furin | ISS | PubMed:1722329 | |
| G7MVY8 | Furin preproprotein | ISS | PubMed:10956649 | |
| G7MVY8 | Furin preproprotein | ISS | PubMed:11861638 | |
| G7MVY8 | Furin preproprotein | ISS | PubMed:95328031 | |
| H2QA34 | Furin (Paired basic amino acid cleaving enzyme) | ISS | PubMed:10956649 | |
| H2QA34 | Furin (Paired basic amino acid cleaving enzyme) | ISS | PubMed:11861638 | |
| H2QA34 | Furin (Paired basic amino acid cleaving enzyme) | ISS | PubMed:95328031 | |
| P09958 | Furin | ISS | PubMed:10956649 | |
| P09958 | Furin | ISS | PubMed:11861638 | |
| P09958 | Furin | ISS | PubMed:95328031 | |
| P23188 | Furin | ISS | PubMed:10956649 | |
| P23188 | Furin | ISS | PubMed:11861638 | |
| P23188 | Furin | ISS | PubMed:95328031 | |
| P23377 | Furin | IGI | PubMed:10956649 | |
| P23377 | Furin | IGI | PubMed:11861638 | |
| PTHR42884:SF14 | A0A8I3RR59 | Neuroendocrine convertase 1 | ISS | |
| F1MFR6 | Neuroendocrine convertase 1 | ISS | ||
| H2QR92 | Neuroendocrine convertase 1 | ISS | ||
| P28840 | Neuroendocrine convertase 1 | ISS | ||
| P29120 | Neuroendocrine convertase 1 | ISS | ||
| P63239 | Neuroendocrine convertase 1 | ISS | ||
| PTHR42884:SF23 | P30432 | Furin-like protease 2 | ISS | PubMed:10956649 |
| PTHR42884:SF3 | P26016 | Furin-like protease 1, isoforms 1_1-X_2 | ISS | PubMed:10956649 |
| P26016 | Furin-like protease 1, isoforms 1_1-X_2 | ISS | PubMed:7737999 |
