PANTHER Pathway  >   FAS signaling pathway >   Mitogen-activated protein kinase kinase 4

Pathway Component Details   
Name: Mitogen-activated protein kinase kinase 4 (MKK4)
Definition: Fas promotes JNK activation through interaction with the Fas-binding protein DAXX and apoptosis signal-regulated kinase 1 (Ask1), and MKK4.
Category ID: P00610
Synonyms:
Upstream: Apoptosis signal regulating kinase 1  (ASK1)
Downstream: c-Jun kinase  (JNK)
Number Families/Subfamilies: 2
Number of Associated Sequences: 7
GO Molecular Function: -
GO Biological Process: -
GO Cellular Component: -
PANTHER protein class: -
References: Medline:12040174  

Sequence Association
Panther Subfamily Associated Sequence Definition Confidence Code Evidence
PTHR48013:SF15 A0A1D5QAU9 Mitogen-activated protein kinase kinase 4 ISS PubMed:10207617  
  A0A1D5QAU9 Mitogen-activated protein kinase kinase 4 ISS PubMed:11730323  
  A0A1D5QAU9 Mitogen-activated protein kinase kinase 4 ISS PubMed:12040174  
  A0A1D5QAU9 Mitogen-activated protein kinase kinase 4 ISS PubMed:7716521  
  A0A3Q1N7I1 Mitogen-activated protein kinase kinase 4 ISS PubMed:10207617  
  A0A3Q1N7I1 Mitogen-activated protein kinase kinase 4 ISS PubMed:11730323  
  A0A3Q1N7I1 Mitogen-activated protein kinase kinase 4 ISS PubMed:12040174  
  A0A3Q1N7I1 Mitogen-activated protein kinase kinase 4 ISS PubMed:7716521  
  B1NA68 Dual specificity mitogen-activated protein kinase kinase 4 ISS PubMed:10207617  
  B1NA68 Dual specificity mitogen-activated protein kinase kinase 4 ISS PubMed:11730323  
  B1NA68 Dual specificity mitogen-activated protein kinase kinase 4 ISS PubMed:12040174  
  B1NA68 Dual specificity mitogen-activated protein kinase kinase 4 ISS PubMed:7716521  
  O61444 MAP kinase kinase 4, isoform A TAS PubMed:11730323  
  O61444 MAP kinase kinase 4, isoform A TAS PubMed:12040174  
  O61444 MAP kinase kinase 4, isoform A TAS PubMed:7600581  
  P47809 Dual specificity mitogen-activated protein kinase kinase 4 ISS PubMed:10207617  
  P47809 Dual specificity mitogen-activated protein kinase kinase 4 ISS PubMed:11730323  
  P47809 Dual specificity mitogen-activated protein kinase kinase 4 ISS PubMed:12040174  
PTHR48013:SF29 H2QCA7 Mitogen-activated protein kinase kinase 4 ISS PubMed:10207617  
  H2QCA7 Mitogen-activated protein kinase kinase 4 ISS PubMed:11730323  
  H2QCA7 Mitogen-activated protein kinase kinase 4 ISS PubMed:12040174  
  H2QCA7 Mitogen-activated protein kinase kinase 4 ISS PubMed:7716521  
  P45985 Dual specificity mitogen-activated protein kinase kinase 4 TAS PubMed:10207617  
  P45985 Dual specificity mitogen-activated protein kinase kinase 4 TAS PubMed:11730323  
  P45985 Dual specificity mitogen-activated protein kinase kinase 4 TAS PubMed:12040174  
  P45985 Dual specificity mitogen-activated protein kinase kinase 4 TAS PubMed:7716521