Pathway Component Details   
Name: Calcium and diacylglycerol-regulated guanine nucleotide exchange factor (CalDAG-GEF)
Definition: A guanine exchange factor for Rap1 activated by increased levels of calcium ion and DAG. CalDAG-GEF converts Rap1 from its GDP-bound inactive state to its active GTP-bound state.
Category ID: P00736
Synonyms:
Upstream:
Downstream: Ras associated protein 1  (Rap1)
Number Families/Subfamilies: 4
Number of Associated Sequences: 24
GO Molecular Function: -
GO Biological Process: -
GO Cellular Component: -
PANTHER protein class: -
References:

Sequence Association
Panther Subfamily Associated Sequence Definition Confidence Code Evidence
PTHR23113:SF157 A0A2J8QF20 RAS guanyl releasing protein 4 ISS PubMed:10835426  
  F6VRK5 RAS guanyl releasing protein 4 ISS PubMed:10835426  
  Q8BTM9 RAS guanyl-releasing protein 4 IDA PubMed:10835426  
  Q8R5I4 RAS guanyl-releasing protein 4 IDA PubMed:10835426  
  Q8TDF6 RAS guanyl-releasing protein 4 IDA PubMed:10835426  
PTHR23113:SF16 A0A2J8QCM9 RAS guanyl releasing protein 2 ISS PubMed:10835426  
  A6N9I4 RAS guanyl-releasing protein 2 ISS PubMed:10835426  
  H9ENK8 RAS guanyl-releasing protein 2 ISS PubMed:10835426  
  P0C643 RAS guanyl-releasing protein 2 ISS PubMed:10835426  
  Q7LDG7 RAS guanyl-releasing protein 2 IDA PubMed:10835426  
  Q9QUG9 RAS guanyl-releasing protein 2 IDA PubMed:10835426  
PTHR23113:SF174 A0A8I3PWD7 RAS guanyl releasing protein 1 ISS PubMed:10835426  
  E1BG59 RAS guanyl releasing protein 1 ISS PubMed:10835426  
  F6TUV4 RAS guanyl releasing protein 1 ISS PubMed:10835426  
  O95267 RAS guanyl-releasing protein 1 IDA PubMed:10835426  
  Q9R1K8 RAS guanyl-releasing protein 1 IDA PubMed:10835426  
  Q9Z1S3 RAS guanyl-releasing protein 1 IDA PubMed:10835426  
PTHR23113:SF178 A0A0G2KAU4 RAS guanyl releasing protein 3 ISS PubMed:10835426  
  A0A2J8L206 RAS guanyl releasing protein 3 ISS PubMed:10835426  
  A0A3Q1LSU3 RAS guanyl releasing protein 3 ISS PubMed:10835426  
  A0A8I3NQI5 RAS guanyl releasing protein 3 ISS PubMed:10835426  
  Q6NZH9 RAS, guanyl releasing protein 3 ISS PubMed:10835426  
  Q8IV61 Ras guanyl-releasing protein 3 ISS PubMed:10835426