Pathway Component Details
| Name: | Apoptotic protease activating factor-1 (Apaf-1) |
| Definition: | Apaf-1 is activated as part of an apoptotic cascase by cytochrome C released following mitochondrial damage stimulated by mutant polyglutamine-expanded huntingtin protein. |
| Category ID: | P00768 |
| Synonyms: | |
| Upstream: |
Cytochrome c
|
| Downstream: | |
| Number Families/Subfamilies: | 1 |
| Number of Associated Sequences: | 6 |
| GO Molecular Function: |
-
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| GO Biological Process: |
-
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| GO Cellular Component: |
-
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| PANTHER protein class: |
-
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| References: |
Sequence Association
| Panther Subfamily | Associated Sequence | Definition | Confidence Code | Evidence |
| PTHR22845:SF5 | A0A3Q1M7I8 | Apoptotic protease-activating factor 1 | ISS | PubMed:10364241 |
| A0A3Q1M7I8 | Apoptotic protease-activating factor 1 | ISS | PubMed:14526190 | |
| A0A3Q1M7I8 | Apoptotic protease-activating factor 1 | ISS | PubMed:9267021 | |
| F6YRV1 | Apoptotic protease-activating factor 1 | ISS | PubMed:10364241 | |
| F6YRV1 | Apoptotic protease-activating factor 1 | ISS | PubMed:14526190 | |
| F6YRV1 | Apoptotic protease-activating factor 1 | ISS | PubMed:9267021 | |
| H2R1S6 | Apoptotic protease-activating factor 1 | ISS | PubMed:10364241 | |
| H2R1S6 | Apoptotic protease-activating factor 1 | ISS | PubMed:14526190 | |
| H2R1S6 | Apoptotic protease-activating factor 1 | ISS | PubMed:9267021 | |
| O14727 | Apoptotic protease-activating factor 1 | TAS | PubMed:10364241 | |
| O14727 | Apoptotic protease-activating factor 1 | TAS | PubMed:14526190 | |
| O88879 | Apoptotic protease-activating factor 1 | TAS | PubMed:14526190 | |
| Q9I9H8 | Apoptotic protease-activating factor 1 | TAS | PubMed:14526190 |
