Pathway Component Details
| Name: | Tumor protein p53 (p53) |
| Definition: | Polyglutamine-expanded mutant huntingtin protein increases transcriptional activation via p53 |
| Category ID: | P00797 |
| Synonyms: | |
| Upstream: |
Disease-associated mutant huntingtin containing polyglutamine expansion
(PolyQ Htt)
|
| Downstream: |
Tumor protein p53 inducible protein 3
(PIG3)
Proline oxidase Bcl-2-binding component 3 (PUMA) Bcl-2-associated X protein (Bax) |
| Number Families/Subfamilies: | 8 |
| Number of Associated Sequences: | 47 |
| GO Molecular Function: |
-
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| GO Biological Process: |
-
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| GO Cellular Component: |
-
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| PANTHER protein class: |
-
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| References: |
Sequence Association
| Panther Subfamily | Associated Sequence | Definition | Confidence Code | Evidence |
| PTHR11447:SF16 | Q7QAB9 | AGAP004319-PA | TAS | PubMed:12932731 |
| PTHR11447:SF21 | B0S576 | Cellular tumor antigen p53 | ISS | PubMed:12932731 |
| B0S576 | Cellular tumor antigen p53 | ISS | PubMed:15197326 | |
| D4AA88 | Tumor protein p73 | ISS | PubMed:12932731 | |
| D4AA88 | Tumor protein p73 | ISS | PubMed:15197326 | |
| F7GA34 | Tumor protein p73 | ISS | PubMed:12932731 | |
| F7GA34 | Tumor protein p73 | ISS | PubMed:15197326 | |
| G3X6J7 | Tumor protein p73 | ISS | PubMed:12932731 | |
| G3X6J7 | Tumor protein p73 | ISS | PubMed:15197326 | |
| O15350 | Tumor protein p73 | TAS | PubMed:12932731 | |
| O15350 | Tumor protein p73 | TAS | PubMed:15197326 | |
| Q9JJP2 | Tumor protein p73 | TAS | PubMed:12932731 | |
| Q9JJP2 | Tumor protein p73 | TAS | PubMed:15197326 | |
| PTHR11447:SF6 | F7F8L3 | Cellular tumor antigen p53 | ISS | PubMed:11099028 |
| F7F8L3 | Cellular tumor antigen p53 | ISS | PubMed:11313951 | |
| F7F8L3 | Cellular tumor antigen p53 | ISS | PubMed:11389839 | |
| F7F8L3 | Cellular tumor antigen p53 | ISS | PubMed:12932731 | |
| H2QC53 | Cellular tumor antigen p53 | ISS | PubMed:11099028 | |
| H2QC53 | Cellular tumor antigen p53 | ISS | PubMed:11313951 | |
| H2QC53 | Cellular tumor antigen p53 | ISS | PubMed:11389839 | |
| H2QC53 | Cellular tumor antigen p53 | ISS | PubMed:12932731 | |
| P02340 | Cellular tumor antigen p53 | TAS | PubMed:11099028 | |
| P02340 | Cellular tumor antigen p53 | TAS | PubMed:11389839 | |
| P02340 | Cellular tumor antigen p53 | TAS | PubMed:12932731 | |
| P04637 | Cellular tumor antigen p53 | TAS | PubMed:11099028 | |
| P04637 | Cellular tumor antigen p53 | TAS | PubMed:11313951 | |
| P04637 | Cellular tumor antigen p53 | TAS | PubMed:11389839 | |
| P04637 | Cellular tumor antigen p53 | TAS | PubMed:12932731 | |
| P67939 | Cellular tumor antigen p53 | TAS | PubMed:11099028 | |
| P67939 | Cellular tumor antigen p53 | TAS | PubMed:11389839 | |
| P67939 | Cellular tumor antigen p53 | TAS | PubMed:12932731 | |
| P67939 | Cellular tumor antigen p53 | TAS | PubMed:14744434 | |
| P79734 | Cellular tumor antigen p53 | ISS | PubMed:11099028 | |
| P79734 | Cellular tumor antigen p53 | ISS | PubMed:11389839 | |
| P79734 | Cellular tumor antigen p53 | ISS | PubMed:12932731 | |
| Q29537 | Cellular tumor antigen p53 | TAS | PubMed:11099028 | |
| Q29537 | Cellular tumor antigen p53 | TAS | PubMed:11389839 | |
| Q29537 | Cellular tumor antigen p53 | TAS | PubMed:12932731 | |
| PTHR11447:SF8 | A0A167VDT2 | Tumor protein 63 (p63) | ISS | PubMed:12932731 |
| A0A167VDT2 | Tumor protein 63 (p63) | ISS | PubMed:15197326 | |
| A0A6I8NIJ8 | Tumor protein 63 (p63) | ISS | PubMed:12932731 | |
| A0A6I8NIJ8 | Tumor protein 63 (p63) | ISS | PubMed:15197326 | |
| A0A8I3PJP7 | Tumor protein 63 (p63) | ISS | PubMed:12932731 | |
| A0A8I3PJP7 | Tumor protein 63 (p63) | ISS | PubMed:15197326 | |
| F1MKA9 | Tumor protein 63 (p63) | ISS | PubMed:12932731 | |
| F1MKA9 | Tumor protein 63 (p63) | ISS | PubMed:15197326 | |
| F7FN64 | Tumor protein 63 (p63) | ISS | PubMed:12932731 | |
| F7FN64 | Tumor protein 63 (p63) | ISS | PubMed:15197326 | |
| H2QNY5 | Tumor protein 63 (p63) | ISS | PubMed:12932731 | |
| H2QNY5 | Tumor protein 63 (p63) | ISS | PubMed:15197326 | |
| O88898 | Tumor protein 63 | TAS | PubMed:12932731 | |
| O88898 | Tumor protein 63 | TAS | PubMed:15197326 | |
| Q8JHZ6 | Tumor protein 63 (p63) | ISS | PubMed:12932731 | |
| Q8JHZ6 | Tumor protein 63 (p63) | ISS | PubMed:15197326 | |
| Q9H3D4 | Tumor protein 63 | TAS | PubMed:12932731 | |
| Q9H3D4 | Tumor protein 63 | TAS | PubMed:15197326 | |
| Q9JJP6 | Tumor protein 63 | TAS | PubMed:12932731 | |
| Q9JJP6 | Tumor protein 63 | TAS | PubMed:15197326 | |
| PTHR12195:SF0 | O44518 | Cytoplasmic FMR1-interacting protein homolog | TAS | |
| Q6UK63 | Protein pirA | TAS | ||
| Q9VF87 | Cytoplasmic FMR1-interacting protein | TAS | ||
| PTHR12195:SF3 | A0A1D5QUW3 | Cytoplasmic FMR1-interacting protein | ISS | |
| A0A2J8NK93 | Cytoplasmic FMR1-interacting protein | ISS | ||
| A0A8I3MKB3 | CYRIA_CYRIB Rac1 binding domain-containing protein | ISS | ||
| F1MX60 | Cytoplasmic FMR1-interacting protein | ISS | ||
| Q5SQX6 | Cytoplasmic FMR1-interacting protein 2 | TAS | ||
| Q96F07 | Cytoplasmic FMR1-interacting protein 2 | TAS | ||
| PTHR12195:SF4 | A0A8I3NVZ2 | Cytoplasmic FMR1-interacting protein | ISS | |
| D4A8H8 | Cytoplasmic FMR1-interacting protein | ISS | ||
| E1BW56 | Cytoplasmic FMR1-interacting protein | ISS | ||
| F6XLX5 | Cytoplasmic FMR1-interacting protein | ISS | ||
| F7ATP3 | Cytoplasmic FMR1-interacting protein | ISS | ||
| F7H5L4 | Cytoplasmic FMR1-interacting protein | ISS | ||
| H2Q913 | Cytoplasmic FMR1-interacting protein | ISS | ||
| Q7L576 | Cytoplasmic FMR1-interacting protein 1 | ISS | ||
| Q7TMB8 | Cytoplasmic FMR1-interacting protein 1 | TAS | ||
| Q90YM8 | Cytoplasmic FMR1-interacting protein 1 homolog | ISS | ||
| PTHR12195:SF5 | A0A1D5QUW3 | Cytoplasmic FMR1-interacting protein | ISS | |
| A0A2J8NK93 | Cytoplasmic FMR1-interacting protein | ISS | ||
| A5A5E1 | Cytoplasmic FMR1-interacting protein | ISS | ||
| A8KBE6 | Cytoplasmic FMR1-interacting protein | ISS | ||
| F1NE09 | Cytoplasmic FMR1-interacting protein | ISS | ||
| F6PFV4 | Cytoplasmic FMR1-interacting protein | ISS |
