Pathway Component Details
| Name: | Son of sevenless (SOS) |
| Definition: | Guanine nucleotide exchange factor (activator) of Ras p21 GTP binding protein |
| Category ID: | P00883 |
| Synonyms: | |
| Upstream: | |
| Downstream: | |
| Number Families/Subfamilies: | 7 |
| Number of Associated Sequences: | 21 |
| GO Molecular Function: |
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| GO Biological Process: |
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| GO Cellular Component: |
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| PANTHER protein class: |
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| References: |
Sequence Association
| Panther Subfamily | Associated Sequence | Definition | Confidence Code | Evidence |
| PTHR23113:SF150 | A0A1D5QE14 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:1631150 |
| A0A1D5QE14 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | 476780 | |
| A0A1D5QE14 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8188688 | |
| A0A1D5QE14 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8479536 | |
| A0A1D5QE14 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8493579 | |
| A0A1D5QE14 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8621483 | |
| A0A1D5QE14 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:92335328 | |
| A0A1D5QE14 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:93262494 | |
| A0A1D5QE14 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:9744561 | |
| A0A8I3MQH2 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:1631150 | |
| A0A8I3MQH2 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | 476780 | |
| A0A8I3MQH2 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8188688 | |
| A0A8I3MQH2 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8479536 | |
| A0A8I3MQH2 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8493579 | |
| A0A8I3MQH2 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8621483 | |
| A0A8I3MQH2 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:92335328 | |
| A0A8I3MQH2 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:93262494 | |
| A0A8I3MQH2 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:9744561 | |
| F1MAI3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:1631150 | |
| F1MAI3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | 476780 | |
| F1MAI3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8188688 | |
| F1MAI3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8479536 | |
| F1MAI3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8493579 | |
| F1MAI3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8621483 | |
| F1MAI3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:92335328 | |
| F1MAI3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:93262494 | |
| F1MAI3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:9744561 | |
| F6URW3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | 476780 | |
| F6URW3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8188688 | |
| F6URW3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8479536 | |
| F6URW3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8493579 | |
| F6URW3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8621483 | |
| F6URW3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:93262494 | |
| F6URW3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:9744561 | |
| F6YCI3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | 476780 | |
| F6YCI3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8188688 | |
| F6YCI3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8479536 | |
| F6YCI3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8493579 | |
| F6YCI3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8621483 | |
| F6YCI3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:93262494 | |
| F6YCI3 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:9744561 | |
| K7CZM1 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:1631150 | |
| K7CZM1 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | 476780 | |
| K7CZM1 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8188688 | |
| K7CZM1 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8479536 | |
| K7CZM1 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8493579 | |
| K7CZM1 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:8621483 | |
| K7CZM1 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:92335328 | |
| K7CZM1 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:93262494 | |
| K7CZM1 | SOS Ras_Rho guanine nucleotide exchange factor 2 | ISS | PubMed:9744561 | |
| Q02384 | Son of sevenless homolog 2 | ISS | PubMed:1631150 | |
| Q02384 | Son of sevenless homolog 2 | ISS | 476780 | |
| Q02384 | Son of sevenless homolog 2 | ISS | PubMed:8188688 | |
| Q02384 | Son of sevenless homolog 2 | ISS | PubMed:8479536 | |
| Q02384 | Son of sevenless homolog 2 | ISS | PubMed:8493579 | |
| Q02384 | Son of sevenless homolog 2 | ISS | PubMed:8621483 | |
| Q02384 | Son of sevenless homolog 2 | ISS | PubMed:92335328 | |
| Q02384 | Son of sevenless homolog 2 | ISS | PubMed:9744561 | |
| Q07890 | Son of sevenless homolog 2 | ISS | 476780 | |
| Q07890 | Son of sevenless homolog 2 | ISS | PubMed:8188688 | |
| Q07890 | Son of sevenless homolog 2 | ISS | PubMed:8479536 | |
| Q07890 | Son of sevenless homolog 2 | ISS | PubMed:8493579 | |
| Q07890 | Son of sevenless homolog 2 | ISS | PubMed:8621483 | |
| Q07890 | Son of sevenless homolog 2 | ISS | PubMed:93262494 | |
| Q07890 | Son of sevenless homolog 2 | ISS | PubMed:9744561 | |
| PTHR23113:SF168 | A0A8I3S3D9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | 476780 |
| A0A8I3S3D9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:7478553 | |
| A0A8I3S3D9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8041791 | |
| A0A8I3S3D9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8188688 | |
| A0A8I3S3D9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8479536 | |
| A0A8I3S3D9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8621483 | |
| A0A8I3S3D9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:9217262 | |
| A0A8I3S3D9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:92335328 | |
| A0A8I3S3D9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:93262494 | |
| A0A8I3S3D9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:9744561 | |
| A0A8I3S3D9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:98043737 | |
| D4A3T0 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | 476780 | |
| D4A3T0 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:7478553 | |
| D4A3T0 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8041791 | |
| D4A3T0 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8188688 | |
| D4A3T0 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8479536 | |
| D4A3T0 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8621483 | |
| D4A3T0 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:9217262 | |
| D4A3T0 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:92335328 | |
| D4A3T0 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:93262494 | |
| D4A3T0 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:9744561 | |
| D4A3T0 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:98043737 | |
| F1N7C3 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | 476780 | |
| F1N7C3 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:7478553 | |
| F1N7C3 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8041791 | |
| F1N7C3 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8188688 | |
| F1N7C3 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8479536 | |
| F1N7C3 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8621483 | |
| F1N7C3 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:9217262 | |
| F1N7C3 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:92335328 | |
| F1N7C3 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:93262494 | |
| F1N7C3 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:9744561 | |
| F1N7C3 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:98043737 | |
| F6QUW1 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | 476780 | |
| F6QUW1 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:7478553 | |
| F6QUW1 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8041791 | |
| F6QUW1 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8188688 | |
| F6QUW1 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8479536 | |
| F6QUW1 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8621483 | |
| F6QUW1 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:9217262 | |
| F6QUW1 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:92335328 | |
| F6QUW1 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:93262494 | |
| F6QUW1 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:9744561 | |
| F6QUW1 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:98043737 | |
| F7BWW9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | 476780 | |
| F7BWW9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:7478553 | |
| F7BWW9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8041791 | |
| F7BWW9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8188688 | |
| F7BWW9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8479536 | |
| F7BWW9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8621483 | |
| F7BWW9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:9217262 | |
| F7BWW9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:92335328 | |
| F7BWW9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:93262494 | |
| F7BWW9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:9744561 | |
| F7BWW9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:98043737 | |
| H2R8U9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | 476780 | |
| H2R8U9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:7478553 | |
| H2R8U9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8041791 | |
| H2R8U9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8188688 | |
| H2R8U9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8479536 | |
| H2R8U9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:8621483 | |
| H2R8U9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:9217262 | |
| H2R8U9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:92335328 | |
| H2R8U9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:93262494 | |
| H2R8U9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:9744561 | |
| H2R8U9 | SOS Ras_Rac guanine nucleotide exchange factor 1 | ISS | PubMed:98043737 | |
| Q07889 | Son of sevenless homolog 1 | TAS | 476780 | |
| Q07889 | Son of sevenless homolog 1 | TAS | PubMed:7478553 | |
| Q07889 | Son of sevenless homolog 1 | TAS | PubMed:8041791 | |
| Q07889 | Son of sevenless homolog 1 | TAS | PubMed:8188688 | |
| Q07889 | Son of sevenless homolog 1 | TAS | PubMed:8479536 | |
| Q07889 | Son of sevenless homolog 1 | TAS | PubMed:8621483 | |
| Q07889 | Son of sevenless homolog 1 | TAS | PubMed:9217262 | |
| Q07889 | Son of sevenless homolog 1 | TAS | PubMed:93262494 | |
| Q07889 | Son of sevenless homolog 1 | TAS | PubMed:9744561 | |
| Q07889 | Son of sevenless homolog 1 | TAS | PubMed:98043737 | |
| Q62245 | Son of sevenless homolog 1 | ISS | 476780 | |
| Q62245 | Son of sevenless homolog 1 | ISS | PubMed:7478553 | |
| Q62245 | Son of sevenless homolog 1 | ISS | PubMed:8041791 | |
| Q62245 | Son of sevenless homolog 1 | ISS | PubMed:8188688 | |
| Q62245 | Son of sevenless homolog 1 | ISS | PubMed:8479536 | |
| Q62245 | Son of sevenless homolog 1 | ISS | PubMed:8621483 | |
| Q62245 | Son of sevenless homolog 1 | ISS | PubMed:9217262 | |
| Q62245 | Son of sevenless homolog 1 | ISS | PubMed:92335328 | |
| Q62245 | Son of sevenless homolog 1 | ISS | PubMed:93262494 | |
| Q62245 | Son of sevenless homolog 1 | ISS | PubMed:9744561 | |
| Q62245 | Son of sevenless homolog 1 | ISS | PubMed:98043737 | |
| PTHR23113:SF319 | Q552M5 | Ras guanine nucleotide exchange factor Y | ISS | |
| PTHR23113:SF333 | Q54PQ4 | Ras guanine nucleotide exchange factor A | ISS | |
| PTHR23113:SF360 | Q8IS21 | Ras guanine nucleotide exchange factor B | ISS | |
| PTHR23113:SF363 | P26675 | Protein son of sevenless | ISS | 476780 |
| P26675 | Protein son of sevenless | ISS | PubMed:8479536 | |
| PTHR23113:SF366 | Q8SSQ0 | Ras guanine nucleotide exchange factor R | ISS |
