Pathway Component Details
| Name: | ELK |
| Definition: | ELK belong to a the ETS oncogene family, that encodes a group of proteins that function as transcription factors under physiologic conditions. When these genes aberrantly expressed, cellular transformation can be caused. In human 3 ELK genes were identified: ELK1/2 ELK3 and ELK4. |
| Category ID: | P01140 |
| Synonyms: | |
| Upstream: |
Extracellular signal-regulated kinase family
(ERK)
|
| Downstream: | |
| Number Families/Subfamilies: | 2 |
| Number of Associated Sequences: | 7 |
| GO Molecular Function: |
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| GO Biological Process: |
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| GO Cellular Component: |
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| PANTHER protein class: |
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| References: | Medline:15014501 OMIM:600246 Medline:8575773 OMIM:311040 OMIM:600247 |
Sequence Association
| Panther Subfamily | Associated Sequence | Definition | Confidence Code | Evidence |
| PTHR11849:SF178 | A4GTP4 | ETS domain-containing protein Elk-1 | ISS | PubMed:10487205 |
| A4GTP4 | ETS domain-containing protein Elk-1 | ISS | PubMed:11050086 | |
| A4GTP4 | ETS domain-containing protein Elk-1 | ISS | PubMed:11151091 | |
| A4GTP4 | ETS domain-containing protein Elk-1 | ISS | PubMed:11279280 | |
| A4GTP4 | ETS domain-containing protein Elk-1 | ISS | PubMed:14670631 | |
| A4GTP4 | ETS domain-containing protein Elk-1 | ISS | 3183861 | |
| A4GTP4 | ETS domain-containing protein Elk-1 | ISS | PubMed:9644975 | |
| P19419 | ETS domain-containing protein Elk-1 | ISS | PubMed:10487205 | |
| P19419 | ETS domain-containing protein Elk-1 | ISS | PubMed:11050086 | |
| P19419 | ETS domain-containing protein Elk-1 | ISS | PubMed:11279280 | |
| P19419 | ETS domain-containing protein Elk-1 | ISS | PubMed:12660819 | |
| P19419 | ETS domain-containing protein Elk-1 | ISS | 3183861 | |
| P41969 | ETS domain-containing protein Elk-1 | ISS | PubMed:10487205 | |
| P41969 | ETS domain-containing protein Elk-1 | ISS | PubMed:11050086 | |
| P41969 | ETS domain-containing protein Elk-1 | ISS | PubMed:11151091 | |
| P41969 | ETS domain-containing protein Elk-1 | ISS | PubMed:11279280 | |
| P41969 | ETS domain-containing protein Elk-1 | ISS | PubMed:14670631 | |
| P41969 | ETS domain-containing protein Elk-1 | ISS | 3183861 | |
| P41969 | ETS domain-containing protein Elk-1 | ISS | PubMed:9644975 | |
| PTHR11849:SF21 | B4F7D4 | ETS transcription factor ELK4 | ISS | PubMed:11846562 |
| F6XTS0 | ETS domain-containing protein Elk-4 isoform a | ISS | PubMed:11846562 | |
| P28324 | ETS domain-containing protein Elk-4 | ISS | PubMed:11846562 | |
| P41158 | ETS domain-containing protein Elk-4 | ISS | PubMed:11846562 |
