Pathway Component Details
| Name: | Platelet-Derived Growth Factor B (PDGF receptor B) |
| Definition: | PDGF(platelet-derived growth factor) receptor is a member of the family of transmembrane receptors with kinase activity which exists two distinct subunits, alpha-PDGF receptor and beta-PDGF receptor. These receptors differ in their affinity for the PDGF-A and PDGF-B chain The alpha-receptor recognizes only PDGF-A chain, but the beta-receptor recognizes PDGF-B as well as PDGF-A chains. Binding of PDGF requires and results in the dimerization of the two receptors that form three distinct receptor patterns(alpha-alpha, alpha-beta, beta-beta). |
| Category ID: | P01156 |
| Synonyms: | |
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| Number Families/Subfamilies: | 3 |
| Number of Associated Sequences: | 10 |
| GO Molecular Function: |
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| GO Biological Process: |
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| GO Cellular Component: |
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| PANTHER protein class: |
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| References: |
Sequence Association
| Panther Subfamily | Associated Sequence | Definition | Confidence Code | Evidence |
| PTHR15360:SF1 | F6RQ55 | Platelet-derived growth factor receptor-like protein | ISS | |
| H2QVT0 | Platelet-derived growth factor receptor-like protein | ISS | ||
| Q15198 | Platelet-derived growth factor receptor-like protein | ISS | ||
| Q5RJP7 | Platelet-derived growth factor receptor-like protein | ISS | ||
| Q6PE55 | Platelet-derived growth factor receptor-like protein | ISS | ||
| PTHR24416:SF53 | A0A1D5Q2Y8 | Platelet-derived growth factor receptor beta | RCA | |
| P05622 | Platelet-derived growth factor receptor beta | RCA | ||
| P09619 | Platelet-derived growth factor receptor beta | RCA | ||
| Q05030 | Platelet-derived growth factor receptor beta | RCA | ||
| PTHR46877:SF11 | A0A1D5QP34 | receptor protein-tyrosine kinase | RCA |
