PANTHER Pathway  >   T cell activation >   C-terminal Src kinase

Pathway Component Details   
Name: C-terminal Src kinase (Csk)
Definition: Csk is a tyrosine kinase that phosphorylates Lck's inhibitory tyrosine residue. In resting cells, this prevents inappropriate initiation of TCR signaling; in stimulated cells it acts as a mode of signal downregulation.
Category ID: P01304
Synonyms:
Upstream:
Downstream: Lck
Number Families/Subfamilies: 1
Number of Associated Sequences: 9
GO Molecular Function: -
GO Biological Process: -
GO Cellular Component: -
PANTHER protein class: -
References:

Sequence Association
Panther Subfamily Associated Sequence Definition Confidence Code Evidence
PTHR24418:SF458 A0A8I3P4Z0 Tyrosine-protein kinase ISS PubMed:11078745  
  A0A8I3P4Z0 Tyrosine-protein kinase ISS PubMed:12665526  
  A0A8I3P4Z0 Tyrosine-protein kinase ISS PubMed:7687537  
  F7GJZ7 Tyrosine-protein kinase ISS PubMed:11078745  
  F7GJZ7 Tyrosine-protein kinase ISS PubMed:12665526  
  F7GJZ7 Tyrosine-protein kinase ISS PubMed:7687537  
  F7GRP2 Tyrosine-protein kinase ISS PubMed:11078745  
  F7GRP2 Tyrosine-protein kinase ISS PubMed:12665526  
  F7GRP2 Tyrosine-protein kinase ISS PubMed:7687537  
  K7AWV1 Tyrosine-protein kinase ISS PubMed:11078745  
  K7AWV1 Tyrosine-protein kinase ISS PubMed:12665526  
  K7AWV1 Tyrosine-protein kinase ISS PubMed:7687537  
  P32577 Tyrosine-protein kinase CSK IDA PubMed:11078745  
  P32577 Tyrosine-protein kinase CSK IDA PubMed:12665526  
  P32577 Tyrosine-protein kinase CSK IDA PubMed:7687537  
  P41239 Tyrosine-protein kinase CSK IDA PubMed:12665526  
  P41239 Tyrosine-protein kinase CSK IDA PubMed:7687537  
  P41240 Tyrosine-protein kinase CSK IDA PubMed:11078745  
  P41240 Tyrosine-protein kinase CSK IDA PubMed:12665526  
  P41240 Tyrosine-protein kinase CSK IDA PubMed:7687537  
  P41241 Tyrosine-protein kinase CSK IDA PubMed:11078745  
  P41241 Tyrosine-protein kinase CSK IDA PubMed:12665526  
  P41241 Tyrosine-protein kinase CSK IDA PubMed:7687537  
  Q0VBZ0 Tyrosine-protein kinase CSK ISS PubMed:11078745  
  Q0VBZ0 Tyrosine-protein kinase CSK ISS PubMed:12665526  
  Q0VBZ0 Tyrosine-protein kinase CSK ISS PubMed:7687537