Pathway Component Details
| Name: | Calcineurin |
| Definition: | Calcineurin is a cytoplasmic phosphatase. Its activity is regulated directly by interactions with Ca-calmodulin. Activated calcineurin dephosphorylates multiple residues in the NF-AT transcription factor, which enables the movement of NF-AT to the nucleus. |
| Category ID: | P01315 |
| Synonyms: | |
| Upstream: | |
| Downstream: |
Nuclear factor of activated T cells
(NFAT)
|
| Number Families/Subfamilies: | 3 |
| Number of Associated Sequences: | 21 |
| GO Molecular Function: |
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| GO Biological Process: |
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| GO Cellular Component: |
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| PANTHER protein class: |
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| References: |
Sequence Association
| Panther Subfamily | Associated Sequence | Definition | Confidence Code | Evidence |
| PTHR45673:SF2 | A0A2I3SD30 | Serine_threonine-protein phosphatase | ISS | PubMed:12015605 |
| A0A2I3SD30 | Serine_threonine-protein phosphatase | ISS | PubMed:12091710 | |
| A0A6I8P6U9 | Serine_threonine-protein phosphatase | ISS | PubMed:12015605 | |
| A0A6I8P6U9 | Serine_threonine-protein phosphatase | ISS | PubMed:12091710 | |
| A5D7T5 | Serine_threonine-protein phosphatase | ISS | PubMed:12015605 | |
| A5D7T5 | Serine_threonine-protein phosphatase | ISS | PubMed:12091710 | |
| F7BBG8 | Serine_threonine-protein phosphatase | ISS | PubMed:12015605 | |
| F7BBG8 | Serine_threonine-protein phosphatase | ISS | PubMed:12091710 | |
| P48454 | Serine_threonine-protein phosphatase 2B catalytic subunit gamma isoform | IGI | PubMed:12015605 | |
| P48454 | Serine_threonine-protein phosphatase 2B catalytic subunit gamma isoform | IGI | PubMed:12091710 | |
| P48455 | Serine_threonine-protein phosphatase 2B catalytic subunit gamma isoform | IGI | PubMed:12015605 | |
| P48455 | Serine_threonine-protein phosphatase 2B catalytic subunit gamma isoform | IGI | PubMed:12091710 | |
| P48455 | Serine_threonine-protein phosphatase 2B catalytic subunit gamma isoform | IGI | PubMed:7532676 | |
| PTHR45673:SF5 | A0A2I3RSP9 | Serine_threonine-protein phosphatase | ISS | PubMed:12015605 |
| A0A2I3RSP9 | Serine_threonine-protein phosphatase | ISS | PubMed:12091710 | |
| A0A2I3RSP9 | Serine_threonine-protein phosphatase | ISS | PubMed:7532676 | |
| A0A8I3PS73 | Serine_threonine-protein phosphatase | ISS | PubMed:12015605 | |
| A0A8I3PS73 | Serine_threonine-protein phosphatase | ISS | PubMed:12091710 | |
| A0A8I3PS73 | Serine_threonine-protein phosphatase | ISS | PubMed:7532676 | |
| F7DKU1 | Serine_threonine-protein phosphatase | ISS | PubMed:12015605 | |
| F7DKU1 | Serine_threonine-protein phosphatase | ISS | PubMed:12091710 | |
| F7DKU1 | Serine_threonine-protein phosphatase | ISS | PubMed:7532676 | |
| P48452 | Protein phosphatase 3 catalytic subunit alpha | IGI | PubMed:12015605 | |
| P48452 | Protein phosphatase 3 catalytic subunit alpha | IGI | PubMed:12091710 | |
| P48452 | Protein phosphatase 3 catalytic subunit alpha | IGI | PubMed:7532676 | |
| P63328 | Protein phosphatase 3 catalytic subunit alpha | ISS | PubMed:12015605 | |
| P63328 | Protein phosphatase 3 catalytic subunit alpha | ISS | PubMed:12091710 | |
| P63328 | Protein phosphatase 3 catalytic subunit alpha | ISS | PubMed:7532676 | |
| P63329 | Protein phosphatase 3 catalytic subunit alpha | IGI | PubMed:12015605 | |
| P63329 | Protein phosphatase 3 catalytic subunit alpha | IGI | PubMed:12091710 | |
| P63329 | Protein phosphatase 3 catalytic subunit alpha | IGI | PubMed:7532676 | |
| Q08209 | Protein phosphatase 3 catalytic subunit alpha | IGI | PubMed:12015605 | |
| Q08209 | Protein phosphatase 3 catalytic subunit alpha | IGI | PubMed:12091710 | |
| Q08209 | Protein phosphatase 3 catalytic subunit alpha | IGI | PubMed:7532676 | |
| PTHR45673:SF7 | A0A8I3MW99 | Serine_threonine-protein phosphatase | ISS | PubMed:12015605 |
| A0A8I3MW99 | Serine_threonine-protein phosphatase | ISS | PubMed:12091710 | |
| A0A8I3MW99 | Serine_threonine-protein phosphatase | ISS | PubMed:7532676 | |
| F6SFC6 | Serine_threonine-protein phosphatase | ISS | PubMed:12015605 | |
| F6SFC6 | Serine_threonine-protein phosphatase | ISS | PubMed:12091710 | |
| F6SFC6 | Serine_threonine-protein phosphatase | ISS | PubMed:7532676 | |
| H2Q237 | Serine_threonine-protein phosphatase | ISS | PubMed:12015605 | |
| H2Q237 | Serine_threonine-protein phosphatase | ISS | PubMed:12091710 | |
| H2Q237 | Serine_threonine-protein phosphatase | ISS | PubMed:7532676 | |
| P16298 | Serine_threonine-protein phosphatase 2B catalytic subunit beta isoform | IGI | PubMed:12015605 | |
| P16298 | Serine_threonine-protein phosphatase 2B catalytic subunit beta isoform | IGI | PubMed:12091710 | |
| P16298 | Serine_threonine-protein phosphatase 2B catalytic subunit beta isoform | IGI | PubMed:7532676 | |
| P20651 | Serine_threonine-protein phosphatase 2B catalytic subunit beta isoform | IGI | PubMed:12015605 | |
| P20651 | Serine_threonine-protein phosphatase 2B catalytic subunit beta isoform | IGI | PubMed:12091710 | |
| P20651 | Serine_threonine-protein phosphatase 2B catalytic subunit beta isoform | IGI | PubMed:7532676 | |
| P48453 | Serine_threonine-protein phosphatase 2B catalytic subunit beta isoform | ISS | PubMed:12015605 | |
| P48453 | Serine_threonine-protein phosphatase 2B catalytic subunit beta isoform | ISS | PubMed:12091710 | |
| P48453 | Serine_threonine-protein phosphatase 2B catalytic subunit beta isoform | ISS | PubMed:7532676 | |
| Q5ZIM8 | Serine_threonine-protein phosphatase | ISS | PubMed:12015605 | |
| Q5ZIM8 | Serine_threonine-protein phosphatase | ISS | PubMed:12091710 | |
| Q5ZIM8 | Serine_threonine-protein phosphatase | ISS | PubMed:7532676 |
