Pathway Component Details
| Name: | Phospholipase C-gamma (PLC-gamma) |
| Definition: | An enzyme that mediates the production of second-messenger molecules derived from phosphatidylinositol 4,5-bisphosphate. |
| Category ID: | P01414 |
| Synonyms: | |
| Upstream: | |
| Downstream: | |
| Number Families/Subfamilies: | 3 |
| Number of Associated Sequences: | 18 |
| GO Molecular Function: |
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| GO Biological Process: |
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| GO Cellular Component: |
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| PANTHER protein class: |
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| References: | OMIM:172420 |
Sequence Association
| Panther Subfamily | Associated Sequence | Definition | Confidence Code | Evidence |
| PTHR10336:SF159 | A8XTZ1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | |
| Q22070 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma plc-3 | ISS | ||
| Q9VXH3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | ||
| PTHR10336:SF173 | A0A1D5R8E9 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:10934033 |
| A0A1D5R8E9 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:11994416 | |
| A0A1D5R8E9 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:12429574 | |
| A0A1D5R8E9 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:12437926 | |
| A0A1D5R8E9 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:12860966 | |
| A0A1D5R8E9 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:14568990 | |
| A0A1D5R8E9 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:15611108 | |
| A0A1D5R8E9 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:1689310 | |
| A0A1D5R8E9 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:2167438 | |
| A0A1D5R8E9 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:7822322 | |
| A0A1D5R8E9 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:90154080 | |
| A0A1D5R8E9 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:90355993 | |
| A0A8I3SCI7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:10934033 | |
| A0A8I3SCI7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:11994416 | |
| A0A8I3SCI7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:12429574 | |
| A0A8I3SCI7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:12437926 | |
| A0A8I3SCI7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:12860966 | |
| A0A8I3SCI7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:14568990 | |
| A0A8I3SCI7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:15611108 | |
| A0A8I3SCI7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:1689310 | |
| A0A8I3SCI7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:2167438 | |
| A0A8I3SCI7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:7822322 | |
| A0A8I3SCI7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:90154080 | |
| A0A8I3SCI7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:90355993 | |
| F6TAH0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:10934033 | |
| F6TAH0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:11994416 | |
| F6TAH0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:12429574 | |
| F6TAH0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:12437926 | |
| F6TAH0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:12860966 | |
| F6TAH0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:14568990 | |
| F6TAH0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:15611108 | |
| F6TAH0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:1689310 | |
| F6TAH0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:2167438 | |
| F6TAH0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:7822322 | |
| F6TAH0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:90154080 | |
| F6TAH0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:90355993 | |
| H2QKD0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:10934033 | |
| H2QKD0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:11994416 | |
| H2QKD0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:12429574 | |
| H2QKD0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:12437926 | |
| H2QKD0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:12860966 | |
| H2QKD0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:14568990 | |
| H2QKD0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:15611108 | |
| H2QKD0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:1689310 | |
| H2QKD0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:2167438 | |
| H2QKD0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:7822322 | |
| H2QKD0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:90154080 | |
| H2QKD0 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:90355993 | |
| P08487 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:10934033 | |
| P08487 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:11994416 | |
| P08487 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:12429574 | |
| P08487 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:12860966 | |
| P08487 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:15611108 | |
| P08487 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:1689310 | |
| P08487 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:7822322 | |
| P08487 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:90154080 | |
| P10686 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:10934033 | |
| P10686 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:11994416 | |
| P10686 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:12429574 | |
| P10686 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:12437926 | |
| P10686 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:12860966 | |
| P10686 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:14568990 | |
| P10686 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:15611108 | |
| P10686 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:7822322 | |
| P19174 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | IDA | PubMed:10934033 | |
| P19174 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | IDA | PubMed:11994416 | |
| P19174 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | IDA | PubMed:12429574 | |
| P19174 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | IDA | PubMed:12860966 | |
| P19174 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | IDA | PubMed:15611108 | |
| P19174 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | IDA | PubMed:2167438 | |
| P19174 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | IDA | PubMed:7822322 | |
| P19174 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | IDA | PubMed:90355993 | |
| Q62077 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:10934033 | |
| Q62077 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:11994416 | |
| Q62077 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:12429574 | |
| Q62077 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:12437926 | |
| Q62077 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:12860966 | |
| Q62077 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:14568990 | |
| Q62077 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:15611108 | |
| Q62077 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:1689310 | |
| Q62077 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:2167438 | |
| Q62077 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:7822322 | |
| Q62077 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:90154080 | |
| Q62077 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | ISS | PubMed:90355993 | |
| PTHR10336:SF25 | A0A2I3SHP7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:10925250 |
| A0A2I3SHP7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:10934033 | |
| A0A2I3SHP7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:12860966 | |
| A0A2I3SHP7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:15611108 | |
| A0A2I3SHP7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:2557343 | |
| A0A2I3SHP7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:7822322 | |
| A0A8I3NZG2 | Phosphoinositide phospholipase C | ISS | PubMed:10925250 | |
| A0A8I3NZG2 | Phosphoinositide phospholipase C | ISS | PubMed:10934033 | |
| A0A8I3NZG2 | Phosphoinositide phospholipase C | ISS | PubMed:12860966 | |
| A0A8I3NZG2 | Phosphoinositide phospholipase C | ISS | PubMed:15611108 | |
| A0A8I3NZG2 | Phosphoinositide phospholipase C | ISS | PubMed:2557343 | |
| A0A8I3NZG2 | Phosphoinositide phospholipase C | ISS | PubMed:7822322 | |
| F1N4C7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:10925250 | |
| F1N4C7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:10934033 | |
| F1N4C7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:12860966 | |
| F1N4C7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:15611108 | |
| F1N4C7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:2557343 | |
| F1N4C7 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:7822322 | |
| F7BVQ1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:10925250 | |
| F7BVQ1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:10934033 | |
| F7BVQ1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:12860966 | |
| F7BVQ1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:15611108 | |
| F7BVQ1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:2557343 | |
| F7BVQ1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:7822322 | |
| F7GH26 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:10925250 | |
| F7GH26 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:10934033 | |
| F7GH26 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:12860966 | |
| F7GH26 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:15611108 | |
| F7GH26 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:2557343 | |
| F7GH26 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma | ISS | PubMed:7822322 | |
| P16885 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | ISS | PubMed:10925250 | |
| P16885 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | ISS | PubMed:10934033 | |
| P16885 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | ISS | PubMed:12860966 | |
| P16885 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | ISS | PubMed:15611108 | |
| P16885 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | ISS | PubMed:2557343 | |
| P16885 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | ISS | PubMed:7822322 | |
| Q8CIH5 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | ISS | PubMed:10925250 | |
| Q8CIH5 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | ISS | PubMed:10934033 | |
| Q8CIH5 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | ISS | PubMed:12860966 | |
| Q8CIH5 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | ISS | PubMed:15611108 | |
| Q8CIH5 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | ISS | PubMed:2557343 | |
| Q8CIH5 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | ISS | PubMed:7822322 |
