Pathway Component Details
| Name: | Histone deacetylase complex subunit Sin3 (Sin3) |
| Definition: | Sin3 is an evolutionarily conserved corepressor that exists in different complexes with the histone deacetylases HDAC1 and HDAC2. It is involved in negative regulation of p53 gene expression. |
| Category ID: | P04622 |
| Synonyms: | |
| Upstream: | |
| Downstream: | |
| Number Families/Subfamilies: | 1 |
| Number of Associated Sequences: | 10 |
| GO Molecular Function: |
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| GO Biological Process: |
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| GO Cellular Component: |
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| PANTHER protein class: |
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| References: | Medline:11784859 OMIM:607776 |
Sequence Association
| Panther Subfamily | Associated Sequence | Definition | Confidence Code | Evidence |
| PTHR12346:SF2 | D3ZBP2 | SIN3 transcription regulator family member A | ISS | PubMed:10441327 |
| E1BX21 | SIN3 transcription regulator family member A | ISS | PubMed:10441327 | |
| F1MTR3 | SIN3 transcription regulator family member A | ISS | PubMed:10441327 | |
| F6TAI6 | Paired amphipathic helix protein Sin3a isoform X1 | ISS | PubMed:10441327 | |
| F7B0D4 | SIN3 transcription regulator family member A | ISS | PubMed:10441327 | |
| F7BFR8 | SIN3 transcription regulator family member A | ISS | PubMed:10441327 | |
| F7H3V1 | Paired amphipathic helix protein Sin3a | ISS | PubMed:10441327 | |
| H2R491 | SIN3 homolog A, transcription regulator | ISS | PubMed:10441327 | |
| Q60520 | Paired amphipathic helix protein Sin3a | ISS | PubMed:10441327 | |
| Q96ST3 | Paired amphipathic helix protein Sin3a | ISS | PubMed:10441327 |
