Pathway Component Details
| Name: | Nicotinic acetylcholine receptor alpha 5 subunit (CHRNA5) |
| Definition: | The nicotinic acetylcholine receptor alpha 5 subunit is a members of the nicotinic acetylcholine receptor (nAChRs) superfamily that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero)pentamers composed of homologous subunits. In dopaminergic neurons, the alpha 5 subunit form a heteropentamer with the alpha 4 (CHRNA4) and beta 2 (CHRNB2) subunit. |
| Category ID: | P06593 |
| Synonyms: | |
| Upstream: | |
| Downstream: | |
| Number Families/Subfamilies: | 1 |
| Number of Associated Sequences: | 7 |
| GO Molecular Function: |
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| GO Biological Process: |
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| GO Cellular Component: |
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| PANTHER protein class: |
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| References: | Medline:12388584 Medline:15155845 OMIM:118505 |
Sequence Association
| Panther Subfamily | Associated Sequence | Definition | Confidence Code | Evidence |
| PTHR18945:SF76 | A0A5F8GVJ8 | Cholinergic receptor nicotinic alpha 5 subunit | ISS | PubMed:85270494 |
| F7G171 | Cholinergic receptor nicotinic alpha 5 subunit | ISS | PubMed:85270494 | |
| P20420 | Neuronal acetylcholine receptor subunit alpha-5 | IDA | PubMed:12388584 | |
| P20420 | Neuronal acetylcholine receptor subunit alpha-5 | IDA | PubMed:85270494 | |
| P30532 | Neuronal acetylcholine receptor subunit alpha-5 | ISS | PubMed:85270494 | |
| Q2MKA5 | Neuronal acetylcholine receptor subunit alpha-5 | ISS | PubMed:12388584 | |
| Q2MKA5 | Neuronal acetylcholine receptor subunit alpha-5 | ISS | PubMed:85270494 | |
| Q5IS51 | Neuronal acetylcholine receptor subunit alpha-5 | ISS | PubMed:12388584 | |
| Q5IS51 | Neuronal acetylcholine receptor subunit alpha-5 | ISS | PubMed:85270494 | |
| Q8SPU7 | Neuronal acetylcholine receptor subunit alpha-5 | ISS | PubMed:12388584 | |
| Q8SPU7 | Neuronal acetylcholine receptor subunit alpha-5 | ISS | PubMed:85270494 |
