PANTHER Gene Information   
Gene Symbol(s): AURKA
Organism: Bos taurus
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Gene Name: Aurora kinase A
Gene ID: ENSBTAG00000013009
Protein ID: Q2TA06
Persistent Id: PTN000682022
Alternate Ids:
Serine/threonine-protein kinase 6 {ECO:0000250|UniProtKB:O14965}(Synonym) XM_005214525(refSeq)
ENSBTAT00000044590(Ensembl_TRS) AURKA{ECO:0000250|UniProtKB:O14965}(Symbol)
AAI11182(EMBL-CDS) DQ334808(EMBL)
83405426(GI) ENSBTAG00000013009(Ensembl)
AURKA_BOVIN(UniProtKB-ID) 2.7.11.1 {ECO:0000250|UniProtKB:P04198}(EC)
504437(GeneID) ENSBTAP00000042073(Ensembl_PRO)
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PANTHER Classification
PANTHER Family: SERINE/THREONINE-PROTEIN KINASE IAL-RELATED (PTHR24350)
PANTHER Subfamily: AURORA KINASE A (PTHR24350:SF5)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process: regulation of cytokinesis
mitotic spindle organization
PANTHER GO-slim Cellular Component: spindle midzone
microtubule associated complex
spindle microtubule
nucleus
kinetochore
centrosome
spindle pole
PANTHER protein class: non-receptor serine/threonine protein kinase
Pathway Categories: No pathway information available
GO MF Complete: histone H3S10 kinase activity, histone H2BS14 kinase activity, histone H2AS1 kinase activity, protein kinase activity, eukaryotic translation initiation factor 2alpha kinase activity, 3-phosphoinositide-dependent protein kinase activity, ribosomal protein S6 kinase activity, DNA-dependent protein kinase activity, ATP binding, histone H2AT120 kinase activity, AMP-activated protein kinase activity, histone H2AS121 kinase activity, histone H3S57 kinase activity, histone H4S1 kinase activity, histone H3T3 kinase activity, histone H2BS36 kinase activity, histone H3S28 kinase activity, histone H3T45 kinase activity, histone H2AXS139 kinase activity, Rho-dependent protein serine/threonine kinase activity, histone H3T11 kinase activity, protein serine kinase activity, histone H3T6 kinase activity
GO BP Complete: cell division, chromatin remodeling, mitotic spindle organization, regulation of cytokinesis, mitotic centrosome separation, cilium disassembly, meiotic spindle organization, positive regulation of mitotic cell cycle
GO CC Complete: contractile ring, ciliary basal body, spindle pole, kinetochore, neuron projection, nucleus, spindle microtubule, centrosome, spindle midzone, mitotic spindle pole, cytoplasm, centriole, chromosome passenger complex, basolateral plasma membrane
Reactome Pathways: APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, Generic Transcription Pathway, AURKA Activation by TPX2, APC/C-mediated degradation of cell cycle proteins, Gene expression (Transcription), TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest, Regulation of TP53 Activity through Phosphorylation, RNA Polymerase II Transcription, Regulation of PLK1 Activity at G2/M Transition, G2/M Transition, Cell Cycle, Regulation of TP53 Activity, Cell Cycle, Mitotic, Transcriptional Regulation by TP53, FBXL7 down-regulates AURKA during mitotic entry and in early mitosis, Mitotic G2-G2/M phases, TP53 Regulates Transcription of Cell Cycle Genes, Regulation of mitotic cell cycle, Interaction between PHLDA1 and AURKA