PANTHER Gene Information   
Gene Symbol(s): MBD2
Organism: Bos taurus
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Gene Name: Methyl-CpG binding domain protein 2
Gene ID: ENSBTAG00000037457.3
Protein ID: G5E683
Persistent Id: PTN000273765
Alternate Ids:
G5E683(Synonym) ENSBTAT00000053498(Ensembl_TRS)
ENSBTAP00000048789(Ensembl_PRO) ENSBTAG00000037457(Ensembl)
G5E683_BOVIN(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: METHYL-CPG BINDING PROTEIN, MBD (PTHR12396)
PANTHER Subfamily: METHYL-CPG-BINDING DOMAIN PROTEIN 2 (PTHR12396:SF5)  
PANTHER GO-slim Molecular Function: nucleotide binding
sequence-specific DNA binding
PANTHER GO-slim Biological Process: negative regulation of transcription by RNA polymerase II
DNA methylation-dependent heterochromatin formation
PANTHER GO-slim Cellular Component: nucleus
PANTHER protein class: chromatin/chromatin-binding, or -regulatory protein
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: identical protein binding, siRNA binding, C2H2 zinc finger domain binding, mRNA binding, chromatin binding, methyl-CpG binding
GO BP Complete: negative regulation of transcription by RNA polymerase II, protein-containing complex assembly, Wnt signaling pathway, positive regulation of Wnt signaling pathway, regulation of cell population proliferation, DNA methylation-dependent constitutive heterochromatin formation, maternal behavior
GO CC Complete: heterochromatin, nucleus, NuRD complex, cytosol
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Negative epigenetic regulation of rRNA expression, Gene expression (Transcription), RNA Polymerase I Promoter Opening, Epigenetic regulation of gene expression, RNA Polymerase I Promoter Clearance, RNA Polymerase I Transcription, NoRC negatively regulates rRNA expression

Orthologs