PANTHER Gene Information   
Gene Symbol(s): MBD2
Organism: Canis lupus familiaris
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Gene Name: Methyl-CpG binding domain protein 2
Gene ID: ENSCAFG00845002942.1
Protein ID: A0A8I3MM96
Persistent Id: PTN008995106
Alternate Ids:
ENSCAFG00845002942(Ensembl) A0A8I3MM96_CANLF(UniProtKB-ID)
ENSCAFT00845005200(Ensembl_TRS) ENSCAFP00845004131(Ensembl_PRO)
A0A8I3MM96(Synonym)
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PANTHER Classification
PANTHER Family: METHYL-CPG BINDING PROTEIN, MBD (PTHR12396)
PANTHER Subfamily: METHYL-CPG-BINDING DOMAIN PROTEIN 2 (PTHR12396:SF5)  
PANTHER GO-slim Molecular Function: nucleotide binding
sequence-specific DNA binding
PANTHER GO-slim Biological Process: negative regulation of transcription by RNA polymerase II
DNA methylation-dependent heterochromatin formation
PANTHER GO-slim Cellular Component: nucleus
PANTHER protein class: chromatin/chromatin-binding, or -regulatory protein
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: DNA binding, methyl-CpG binding
GO BP Complete: negative regulation of transcription by RNA polymerase II, DNA methylation-dependent constitutive heterochromatin formation
GO CC Complete: nucleus, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Gene expression (Transcription), Negative epigenetic regulation of rRNA expression, RNA Polymerase I Promoter Clearance, NoRC negatively regulates rRNA expression, RNA Polymerase I Transcription, RNA Polymerase I Promoter Opening, Epigenetic regulation of gene expression

Orthologs