PANTHER Gene Information   
Gene Symbol(s): hda-1
Organism: Caenorhabditis elegans
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Gene Name: Histone deacetylase 1
Gene ID: WBGene00001834
Protein ID: O17695
Persistent Id: PTN000066264
Alternate Ids:
WBGene00001834(WormBase) HDA1_CAEEL(UniProtKB-ID)
C53A5(WormBase_TRS) CE08952(WormBase_PRO)
hda-1{ECO:0000312|WormBase:C53A5.3}(Symbol) C53A5.3(Ensembl_PRO)
HDA1(Synonym) C53A5.3(Ensembl_TRS)
Z81486(EMBL) CAB03984(EMBL-CDS)
3023926(GI) WBGene00001834(Ensembl)
NM_074198(refSeq) 3.5.1.98(EC)
179959(GeneID)
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PANTHER Classification
PANTHER Family: HISTONE DEACETYLASE HDAC1-RELATED (PTHR10625)
PANTHER Subfamily: HISTONE DEACETYLASE 1 (PTHR10625:SF29)  
PANTHER GO-slim Molecular Function: histone deacetylase activity
PANTHER GO-slim Biological Process: heterochromatin formation
PANTHER GO-slim Cellular Component: histone deacetylase complex
transcription regulator complex
SWI/SNF superfamily-type complex
PANTHER protein class:
Pathway Categories: Wnt signaling pathway
   Histone deacetylase

GO MF Complete: protein binding, histone deacetylase activity, RNA polymerase II-specific DNA-binding transcription factor binding, transcription corepressor activity, hydrolase activity
GO BP Complete: negative regulation of vulval development, determination of adult lifespan, embryo development ending in birth or egg hatching, negative regulation of stress response to copper ion, hermaphrodite somatic sex determination, nematode male tail tip morphogenesis, embryonic digestive tract morphogenesis, chromatin organization, negative regulation of Notch signaling pathway, positive regulation of transcription by RNA polymerase II, negative regulation of transcription by RNA polymerase II, gonad development, negative regulation of Ras protein signal transduction, regulation of cell differentiation, heterochromatin formation, regulation of innate immune response, cell differentiation, regulation of cell migration, mitochondrial unfolded protein response
GO CC Complete: nucleus, germ cell nucleus, cytoplasm, NuRD complex, histone deacetylase complex, chromosome, chromatin
Reactome Pathways: Signal Transduction, Signaling by ALK, RNA Polymerase II Transcription, Transcriptional Regulation by TP53, Regulation of TP53 Activity, STAT3 nuclear events downstream of ALK signaling, Regulation of TP53 Activity through Acetylation, SUMOylation, Generic Transcription Pathway, SUMO E3 ligases SUMOylate target proteins, SUMOylation of chromatin organization proteins, Gene expression (Transcription), Signaling by Receptor Tyrosine Kinases, Post-translational protein modification, Metabolism of proteins