PANTHER Gene Information   
Gene Symbol(s): HDAC1
Organism: Gallus gallus
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Gene Name: Histone deacetylase 1
Gene ID: ENSGALG00010017415
Protein ID: P56517
Persistent Id: PTN000066240
Alternate Ids:
HDAC1_CHICK(UniProtKB-ID) HDAC1A(Synonym)
3.5.1.- {ECO:0000250|UniProtKB:Q13547}(EC) NP_989487(refSeq)
ENSGALT00010042088(Ensembl_TRS) HDAC1(Symbol)
AAC00504(EMBL-CDS) AF039751(EMBL)
2827430(GI) ENSGALG00010017415(Ensembl)
ENSGALP00010024643(Ensembl_PRO) 373961(GeneID)
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PANTHER Classification
PANTHER Family: HISTONE DEACETYLASE HDAC1-RELATED (PTHR10625)
PANTHER Subfamily: HISTONE DEACETYLASE 1 (PTHR10625:SF49)  
PANTHER GO-slim Molecular Function: histone deacetylase activity
PANTHER GO-slim Biological Process: heterochromatin formation
PANTHER GO-slim Cellular Component: histone deacetylase complex
transcription regulator complex
SWI/SNF superfamily-type complex
PANTHER protein class:
Pathway Categories: Wnt signaling pathway
   Histone deacetylase
p53 pathway
   Histon deacetylase 1
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: histone deacetylase binding, tubulin deacetylase activity, RNA polymerase II core promoter sequence-specific DNA binding, histone H3K4 deacetylase activity, hydrolytic mechanism, transcription corepressor binding, NF-kappaB binding, histone H4K8 deacetylase activity, hydrolytic mechanism, histone H4K16 deacetylase activity, hydrolytic mechanism, histone H4K5 deacetylase activity, hydrolytic mechanism, p53 binding, histone H4K12 deacetylase activity, hydrolytic mechanism, protein lysine delactylase activity, histone deacetylase activity, histone decrotonylase activity, promoter-specific chromatin binding, transcription corepressor activity, metal ion binding, histone H3K14 deacetylase activity, hydrolytic mechanism, Krueppel-associated box domain binding, histone H3K9 deacetylase activity, hydrolytic mechanism, protein lysine deacetylase activity, DNA-binding transcription factor binding, E-box binding
GO BP Complete: negative regulation by host of viral transcription, oligodendrocyte differentiation, neuron differentiation, endoderm development, positive regulation of cell population proliferation, fungiform papilla formation, negative regulation of canonical NF-kappaB signal transduction, chromatin organization, positive regulation of transcription by RNA polymerase II, eyelid development in camera-type eye, DNA methylation-dependent constitutive heterochromatin formation, embryonic digit morphogenesis, positive regulation of oligodendrocyte differentiation, negative regulation of androgen receptor signaling pathway, negative regulation of transcription by RNA polymerase II, negative regulation of canonical Wnt signaling pathway, circadian regulation of gene expression, epidermal cell differentiation, heterochromatin formation, negative regulation of intrinsic apoptotic signaling pathway
GO CC Complete: heterochromatin, nucleus, cytoplasm, transcription repressor complex, NuRD complex, histone deacetylase complex, cytosol, neuronal cell body, Sin3-type complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Intracellular signaling by second messengers, TCF dependent signaling in response to WNT, RNA Polymerase I Transcription, RNA Polymerase I Transcription Initiation, Hemostasis, Formation of the beta-catenin:TCF transactivating complex, Estrogen-dependent gene expression, Metabolism of proteins, ESR-mediated signaling, Chromatin organization, Regulation of PTEN gene transcription, HDACs deacetylate histones, SUMOylation, SUMOylation of chromatin organization proteins, Mitotic G1 phase and G1/S transition, G0 and Early G1, Generic Transcription Pathway, Signaling by WNT, RNA Polymerase II Transcription, Cell Cycle, Mitotic, RNA Polymerase I Promoter Clearance, Transcriptional regulation by RUNX1, Post-translational protein modification, PTEN Regulation, Notch-HLH transcription pathway, SUMO E3 ligases SUMOylate target proteins, Factors involved in megakaryocyte development and platelet production, Signaling by Receptor Tyrosine Kinases, PIP3 activates AKT signaling, Chromatin modifying enzymes, Signaling by ALK, Signal Transduction, Signaling by Nuclear Receptors, Gene expression (Transcription), RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function, Deactivation of the beta-catenin transactivating complex, STAT3 nuclear events downstream of ALK signaling, Cell Cycle

Orthologs