PANTHER Gene Information   
Gene Symbol(s): HDAC2
Organism: Sus scrofa
View Gene in Tree
Tree
Tree
Gene Name: Histone deacetylase 2
Gene ID: ENSSSCG00000004432.5
Protein ID: F1RZK8
Persistent Id: PTN001318740
Alternate Ids:
100156170(GeneID) F1RZK8(Synonym)
ENSSSCP00000004781(Ensembl_PRO) ENSSSCG00000004432(Ensembl)
F1RZK8_PIG(UniProtKB-ID) ENSSSCT00000004897(Ensembl_TRS)
335279374(GI) XP_001925353(refSeq)
Show All

PANTHER Classification
PANTHER Family: HISTONE DEACETYLASE HDAC1-RELATED (PTHR10625)
PANTHER Subfamily: HISTONE DEACETYLASE 2 (PTHR10625:SF3)  
PANTHER GO-slim Molecular Function: histone deacetylase activity
PANTHER GO-slim Biological Process: heterochromatin formation
PANTHER GO-slim Cellular Component: histone deacetylase complex
transcription regulator complex
SWI/SNF superfamily-type complex
PANTHER protein class:
Pathway Categories: Wnt signaling pathway
   Histone deacetylase
p53 pathway
   Histon deacetylase 1

GO MF Complete: histone deacetylase binding, tubulin deacetylase activity, histone H3K4 deacetylase activity, hydrolytic mechanism, NF-kappaB binding, histone H4K8 deacetylase activity, hydrolytic mechanism, histone H4K16 deacetylase activity, hydrolytic mechanism, histone H4K5 deacetylase activity, hydrolytic mechanism, histone H4K12 deacetylase activity, hydrolytic mechanism, histone deacetylase activity, histone decrotonylase activity, histone binding, metal ion binding, protein de-2-hydroxyisobutyrylase activity, histone H3K14 deacetylase activity, hydrolytic mechanism, histone H3K9 deacetylase activity, hydrolytic mechanism
GO BP Complete: negative regulation of transcription by RNA polymerase II, negative regulation of transcription by competitive promoter binding, heterochromatin formation, positive regulation of cell population proliferation, positive regulation of proteolysis, positive regulation of transcription by RNA polymerase II
GO CC Complete: chromosome, telomeric region, cytoplasm, NuRD complex, ESC/E(Z) complex, Sin3-type complex
Reactome Pathways: Transcriptional Regulation by MECP2, Signaling by ALK, Signal Transduction, STAT3 nuclear events downstream of ALK signaling, Metabolism of proteins, Chromatin organization, Notch-HLH transcription pathway, Post-translational protein modification, Gene expression (Transcription), RNA Polymerase I Promoter Clearance, Factors involved in megakaryocyte development and platelet production, HDACs deacetylate histones, Intracellular signaling by second messengers, SUMO E3 ligases SUMOylate target proteins, Regulation of MECP2 expression and activity, RNA Polymerase II Transcription, SUMOylation of chromatin organization proteins, Hemostasis, Transcriptional Regulation by TP53, SUMOylation, Regulation of TP53 Activity through Acetylation, Regulation of TP53 Activity, Regulation of PTEN gene transcription, RNA Polymerase I Transcription, RNA Polymerase I Transcription Initiation, Generic Transcription Pathway, Signaling by Receptor Tyrosine Kinases, PTEN Regulation, Chromatin modifying enzymes, PIP3 activates AKT signaling