PANTHER Gene Information

Gene Symbol(s):

hlh-8

Organism:

Caenorhabditis elegans

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Gene Name:

Twist-related protein

Gene ID:

WBGene00001953

Protein ID:

Q11094

Persistent Id:

PTN000598598

Alternate Ids:

AAC26105(EMBL-CDS)	NP_509367(refSeq)
21264539(GI)	CeTwist(Synonym)
C02B8.4(Ensembl_PRO)	WBGene00001953(Ensembl)
C02B8.4(Ensembl_TRS)	C02B8(WormBase_TRS)
CE24777(WormBase_PRO)	AF037063(EMBL)
WBGene00001953(WormBase)	hlh-8(Symbol)
TWIST_CAEEL(UniProtKB-ID)	181069(GeneID)
O76255(AltAccession)
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PANTHER Classification

PANTHER Family:	BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST (PTHR23349)
PANTHER Subfamily:	PROTEIN TWIST (PTHR23349:SF50)
PANTHER GO-slim Molecular Function:	DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II transcription regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process:	regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class:	basic helix-loop-helix transcription factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, protein dimerization activity, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	positive regulation of DNA-templated transcription, cell differentiation, vulval cell fate specification, developmental process, positive regulation of transcription by RNA polymerase II, regulation of transcription by RNA polymerase II, mesodermal cell fate specification
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=12428\|UniProtKB=Q15672	Homo sapiens	LDO
PANTR\|Gene=TWIST1\|UniProtKB=Q8MI03	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000018960.6\|UniProtKB=H2R5G5	Pan troglodytes	LDO
GORGO\|Gene=TWIST1\|UniProtKB=Q8MI06	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=98872\|UniProtKB=P26687	Mus musculus	LDO
RAT\|RGD=621455\|UniProtKB=Q9EPJ1	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000046922.2\|UniProtKB=G3N341	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000058909.1\|UniProtKB=A0A8W4FJQ2	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000033207.2\|UniProtKB=A0A1W5	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000039287.2\|UniProtKB=A0A2I2U7P8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845007076.1\|UniProtKB=A0A8I3N2Z5	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000023924.4\|UniProtKB=F7BD28	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000009614.3\|UniProtKB=F6Z428	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010003808.1\|UniProtKB=A0A8V0XEN1	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000011825.2\|UniProtKB=A7Z092	Anolis carolinensis	LDO
ORYLA\|Ensembl=ENSORLG00000004012.2\|UniProtKB=H2LGB8	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-000210-6\|UniProtKB=Q9PTE3	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000007251.2\|UniProtKB=Q6I701	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050417-357\|UniProtKB=Q568M7	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000018350.1\|UniProtKB=W5NP92	lepisosteus oculatus	LDO
CHICK\|Ensembl=ENSGALG00010023275.1\|UniProtKB=A7Z095	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000015086.3\|UniProtKB=H9GLW5	Anolis carolinensis	O
XENLA\|Gene=LOC108708625\|UniProtKB=A0A1L8HIB6	Xenopus laevis	O
XENLA\|Gene=twist2.S\|UniProtKB=A0A1L8H9Z2	Xenopus laevis	O
ORYLA\|Ensembl=ENSORLG00000029893.1\|UniProtKB=A7Z0A2	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000016373.2\|UniProtKB=H2MP40	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-000210-7\|UniProtKB=Q6DBZ9	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000018198.1\|UniProtKB=W5NNU0	lepisosteus oculatus	O
HUMAN\|HGNC=20670\|UniProtKB=Q8WVJ9	Homo sapiens	O
MACMU\|Ensembl=ENSMMUG00000021909.4\|UniProtKB=F6V9S4	Macaca mulatta	O
MOUSE\|MGI=MGI=104685\|UniProtKB=Q9D030	Mus musculus	O
RAT\|RGD=621286\|UniProtKB=P97831	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000021444.6\|UniProtKB=A4IFM6	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000016343.5\|UniProtKB=F2Z5R9	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000038446.2\|UniProtKB=A0A3Q2IDE9	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000037141.2\|UniProtKB=A0A2I2UDZ8	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845030266.1\|UniProtKB=A0A8I3Q5Z9	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000001412.3\|UniProtKB=F6YYE6	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000012950.2\|UniProtKB=F6ZBG4	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010013612.1\|UniProtKB=Q9YH69	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000009715.3\|UniProtKB=G1KJ81	Anolis carolinensis	O
XENLA\|Gene=twist1\|UniProtKB=P13903	Xenopus laevis	O
XENLA\|Gene=twist1.L\|UniProtKB=A1L2X6	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-479802\|UniProtKB=Q9PUL7	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000018096.2\|UniProtKB=H2MV39	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-980526-235\|UniProtKB=Q5XJI8	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000017835.1\|UniProtKB=W5NMS9	lepisosteus oculatus	O
BRAFL\|Gene=LOC118424081\|UniProtKB=A0A9J7LTS7	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC753325\|UniProtKB=A7Z0B7	Strongylocentrotus purpuratus	LDO
CAEBR\|WormBase=WBGene00036707\|UniProtKB=A8XQ12	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00204371\|UniProtKB=A0A2A6CI47	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0003900\|UniProtKB=P10627	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP011985\|UniProtKB=A0A1S4H819	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC014598\|UniProtKB=D6WMV6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_320202\|UniProtKB=E9GP58	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW009433\|UniProtKB=B7PZD3	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG155122\|UniProtKB=T1ELH0	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g243969\|UniProtKB=A7SAI0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g234699\|UniProtKB=Q6S5G7	Nematostella vectensis	LDO
CRYNJ\|EnsemblGenome=CNH00430\|UniProtKB=Q5KCB3	Cryptococcus neoformans	O