PANTHER Gene Information   
Gene Symbol(s): TWIST1
Organism: Canis lupus familiaris
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Gene Name: Twist-related protein 1
Gene ID: ENSCAFG00845007076.1
Protein ID: A0A8I3N2Z5
Persistent Id: PTN009071134
Alternate Ids:
ENSCAFG00845007076(Ensembl) ENSCAFP00845009804(Ensembl_PRO)
A0A8I3N2Z5(Synonym) ENSCAFT00845012550(Ensembl_TRS)
A0A8I3N2Z5_CANLF(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST (PTHR23349)
PANTHER Subfamily: TWIST-RELATED PROTEIN 1 (PTHR23349:SF64)  
PANTHER GO-slim Molecular Function: DNA-binding transcription factor activity, RNA polymerase II-specific
RNA polymerase II transcription regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process: regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class: basic helix-loop-helix transcription factor
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: transcription coregulator binding, protein domain specific binding, protein homodimerization activity, histone deacetylase binding, DNA-binding transcription repressor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, bHLH transcription factor binding, E-box binding
GO BP Complete: cranial suture morphogenesis, positive regulation of monocyte chemotactic protein-1 production, negative regulation of double-strand break repair, negative regulation of miRNA transcription, embryonic camera-type eye formation, cardiac neural crest cell migration involved in outflow tract morphogenesis, positive regulation of transcription by RNA polymerase II, negative regulation of striated muscle tissue development, embryonic digit morphogenesis, negative regulation of osteoblast differentiation, negative regulation of transcription by RNA polymerase II, endocardial cushion morphogenesis, neuron migration, neural tube closure, in utero embryonic development, negative regulation of skeletal muscle tissue development, negative regulation of macrophage cytokine production, osteoblast differentiation, energy homeostasis, positive regulation of tumor necrosis factor production, cellular response to hypoxia, embryonic forelimb morphogenesis, cell proliferation involved in heart valve development, negative regulation of tumor necrosis factor production, embryonic hindlimb morphogenesis, regulation of bone mineralization, negative regulation of peroxisome proliferator activated receptor signaling pathway, negative regulation of cellular senescence, negative regulation of DNA damage response, signal transduction by p53 class mediator, aortic valve morphogenesis, positive regulation of fatty acid beta-oxidation, mitral valve morphogenesis, embryonic cranial skeleton morphogenesis, eyelid development in camera-type eye, negative regulation of apoptotic process, positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation, positive regulation of DNA-templated transcription initiation, positive regulation of interleukin-6 production, positive regulation of cell migration, negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO CC Complete: nucleus
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: -

Orthologs