PANTHER Gene Information   
Gene Symbol(s): TWIST1
Organism: Monodelphis domestica
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Gene Name: Twist-related protein 1
Gene ID: ENSMODG00000023924.4
Protein ID: F7BD28
Persistent Id: PTN001516441
Alternate Ids:
F7BD28(Synonym) F7BD28_MONDO(UniProtKB-ID)
ENSMODT00000001743(Ensembl_TRS) ENSMODG00000023924(Ensembl)
ENSMODP00000001708(Ensembl_PRO)
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PANTHER Classification
PANTHER Family: BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST (PTHR23349)
PANTHER Subfamily: TWIST-RELATED PROTEIN 1 (PTHR23349:SF64)  
PANTHER GO-slim Molecular Function: DNA-binding transcription factor activity, RNA polymerase II-specific
RNA polymerase II transcription regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process: regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class: basic helix-loop-helix transcription factor
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: protein domain specific binding, identical protein binding, protein homodimerization activity, histone deacetylase binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, cis-regulatory region sequence-specific DNA binding, DNA-binding transcription repressor activity, protein dimerization activity, DNA-binding transcription factor activity, RNA polymerase II-specific, bHLH transcription factor binding, transcription coregulator binding, DNA-binding transcription factor activity, DNA-binding transcription factor binding, E-box binding
GO BP Complete: cranial suture morphogenesis, cardiac neural crest cell migration involved in outflow tract morphogenesis, negative regulation of striated muscle tissue development, embryonic digit morphogenesis, endocardial cushion morphogenesis, negative regulation of DNA-templated transcription, ossification, in utero embryonic development, negative regulation of skeletal muscle tissue development, negative regulation of macrophage cytokine production, energy homeostasis, positive regulation of tumor necrosis factor production, cellular response to hypoxia, embryonic forelimb morphogenesis, cell proliferation involved in heart valve development, negative regulation of tumor necrosis factor production, embryonic hindlimb morphogenesis, regulation of bone mineralization, negative regulation of peroxisome proliferator activated receptor signaling pathway, negative regulation of DNA damage response, signal transduction by p53 class mediator, aortic valve morphogenesis, positive regulation of fatty acid beta-oxidation, mitral valve morphogenesis, positive regulation of gene expression, positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation, positive regulation of interleukin-6 production, positive regulation of cell migration, negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction, positive regulation of monocyte chemotactic protein-1 production, negative regulation of double-strand break repair, negative regulation of miRNA transcription, embryonic camera-type eye formation, positive regulation of transcription by RNA polymerase II, negative regulation of osteoblast differentiation, negative regulation of transcription by RNA polymerase II, positive regulation of epithelial to mesenchymal transition, embryonic limb morphogenesis, neuron migration, neural tube closure, stem cell differentiation, negative regulation of cell differentiation, osteoblast differentiation, developmental process, hindlimb morphogenesis, negative regulation of cellular senescence, embryonic cranial skeleton morphogenesis, cardiac neural crest cell development involved in outflow tract morphogenesis, embryonic skeletal system morphogenesis, eyelid development in camera-type eye, regulation of transcription by RNA polymerase II, negative regulation of apoptotic process, positive regulation of DNA-templated transcription initiation, positive regulation of cell motility
GO CC Complete: nucleus
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: -

Orthologs