PANTHER Gene Information

Gene Symbol(s):

DLL3

Organism:

Canis lupus familiaris

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Gene Name:

Delta like canonical Notch ligand 3

Gene ID:

ENSCAFG00845004619.1

Protein ID:

A0A8I3MXZ5

Persistent Id:

PTN009076545

Alternate Ids:

A0A8I3MXZ5(Synonym)	ENSCAFG00845004619(Ensembl)
A0A8I3MXZ5_CANLF(UniProtKB-ID)	ENSCAFT00845008263(Ensembl_TRS)
ENSCAFP00845006497(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	NOTCH LIGAND FAMILY MEMBER (PTHR24044)
PANTHER Subfamily:	DELTA-LIKE PROTEIN 3 (PTHR24044:SF308)
PANTHER GO-slim Molecular Function:	signaling receptor binding
PANTHER GO-slim Biological Process:	negative regulation of Notch signaling pathway Notch signaling pathway
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	intercellular signal molecule

Pathway Categories:

Angiogenesis

Delta

Notch signaling pathway

Delta

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	calcium ion binding, Notch binding
GO BP Complete:	Notch signaling pathway, negative regulation of Notch signaling pathway
GO CC Complete:	membrane, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=2909\|UniProtKB=Q9NYJ7	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000010975.4\|UniProtKB=A0A2I3RGF5	Pan troglodytes	LDO
PANTR\|Ensembl=ENSPTRG00000043273.1\|UniProtKB=A0A2I3SFR1	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000014462.3\|UniProtKB=A0A2I2ZIN7	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000019093.4\|UniProtKB=F6TFV4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1096877\|UniProtKB=O88516	Mus musculus	LDO
RAT\|RGD=70953\|UniProtKB=O88671	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000010483.6\|UniProtKB=E1B9I8	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000002987.5\|UniProtKB=A0A480YVK2	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000007731.4\|UniProtKB=F7DLM4	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000010746.6\|UniProtKB=A0A2I2UXY8	Felis catus	LDO
ORNAN\|Ensembl=ENSOANG00000049187.1\|UniProtKB=A0A6I8PC71	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000000787.4\|UniProtKB=H9G4A0	Anolis carolinensis	LDO
ORYLA\|Ensembl=ENSORLG00000000415.2\|UniProtKB=A0A3B3HAS1	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000013530.2\|UniProtKB=H2MEF7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000000378.2\|UniProtKB=H2L3Y4	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-000125-4\|UniProtKB=Q9IAT6	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-980526-114\|UniProtKB=O57409	Danio rerio	LDO
CIOIN\|Ensembl=ENSCING00000004194.3\|UniProtKB=F7ALL8	Ciona intestinalis	O
BRAFL\|Gene=LOC118417211\|UniProtKB=A0A9J7LBM6	Branchiostoma floridae	O
CAEEL\|WormBase=WBGene00015328\|UniProtKB=O44443	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG19989\|UniProtKB=A8XWV9	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG19981\|UniProtKB=A8XWV4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00106762\|UniProtKB=A0A2A6CBX6	Pristionchus pacificus	O
CAEBR\|WormBase=WBGene00031967\|UniProtKB=A8XBI4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00275663\|UniProtKB=A0A2A6BU86	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00095068\|UniProtKB=A0A2A6BLX6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00097058\|UniProtKB=A0A2A6BDF7	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00003001\|UniProtKB=P14585	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG06809\|UniProtKB=A8X345	Caenorhabditis briggsae	O
IXOSC\|EnsemblGenome=ISCW020634\|UniProtKB=B7Q2M9	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG80798\|UniProtKB=T1G456	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG133373\|UniProtKB=T1EI04	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG85694\|UniProtKB=T1G618	helobdella robusta	O
DROME\|FlyBase=FBgn0021742\|UniProtKB=Q9VZ44	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP010940\|UniProtKB=A0A1S4H5C2	Anopheles gambiae	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_39669\|UniProtKB=E9FR30	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_323318\|UniProtKB=E9GYJ2	Daphnia pulex	O
DROME\|FlyBase=FBgn0000463\|UniProtKB=P10041	Drosophila melanogaster	O
TRICA\|EnsemblGenome=TC004114\|UniProtKB=D6W6S0	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_63051\|UniProtKB=E9HI96	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW013622\|UniProtKB=B7QHQ8	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG77153\|UniProtKB=T1G2T6	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g216602\|UniProtKB=A7SS38	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g128497\|UniProtKB=A7SR75	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_38707\|UniProtKB=A9V9N1	Monosiga brevicollis	O
GIAIC\|EnsemblGenome=GL50803_24512\|UniProtKB=A8B4D5	Giardia intestinalis	O
CHLRE\|EnsemblGenome=CHLRE_16g690095v5\|UniProtKB=A0A2K3CW78	Chlamydomonas reinhardtii	O