PANTHER Gene Information

Gene Symbol(s):

20196204

Organism:

helobdella robusta

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Gene Name:

EGF-like domain-containing protein

Gene ID:

HelroG133373

Protein ID:

T1EI04

Persistent Id:

PTN008602657

Alternate Ids:

HelroT133373(Ensembl_TRS)	HelroP133373(Ensembl_PRO)
XP_009015542(refSeq)	T1EI04_HELRO(UniProtKB-ID)
675859964(GI)	T1EI04(Synonym)
ESO06174(EMBL-CDS)	AMQM01000573(EMBL)
20196204(GeneID)	HelroG133373(Ensembl)
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PANTHER Classification

PANTHER Family:	NOTCH LIGAND FAMILY MEMBER (PTHR24044)
PANTHER Subfamily:	EGF-LIKE DOMAIN-CONTAINING PROTEIN (PTHR24044:SF504)
PANTHER GO-slim Molecular Function:	signaling receptor binding
PANTHER GO-slim Biological Process:	negative regulation of Notch signaling pathway Notch signaling pathway
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	intercellular signal molecule

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	calcium ion binding, Notch binding
GO BP Complete:	Notch signaling pathway, negative regulation of Notch signaling pathway
GO CC Complete:	plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=2909\|UniProtKB=Q9NYJ7	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000010975.4\|UniProtKB=A0A2I3RGF5	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000043273.1\|UniProtKB=A0A2I3SFR1	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000014462.3\|UniProtKB=A0A2I2ZIN7	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000019093.4\|UniProtKB=F6TFV4	Macaca mulatta	O
MOUSE\|MGI=MGI=1096877\|UniProtKB=O88516	Mus musculus	O
RAT\|RGD=70953\|UniProtKB=O88671	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000010483.6\|UniProtKB=E1B9I8	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000002987.5\|UniProtKB=A0A480YVK2	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000007731.4\|UniProtKB=F7DLM4	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000010746.6\|UniProtKB=A0A2I2UXY8	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845004619.1\|UniProtKB=A0A8I3MXZ5	Canis lupus familiaris	O
ORNAN\|Ensembl=ENSOANG00000049187.1\|UniProtKB=A0A6I8PC71	Ornithorhynchus anatinus	O
ANOCA\|Ensembl=ENSACAG00000000787.4\|UniProtKB=H9G4A0	Anolis carolinensis	O
ORYLA\|Ensembl=ENSORLG00000000415.2\|UniProtKB=A0A3B3HAS1	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000013530.2\|UniProtKB=H2MEF7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000000378.2\|UniProtKB=H2L3Y4	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-000125-4\|UniProtKB=Q9IAT6	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-980526-114\|UniProtKB=O57409	Danio rerio	O
HUMAN\|HGNC=2910\|UniProtKB=Q9NR61	Homo sapiens	O
GORGO\|Ensembl=ENSGGOG00000028605.2\|UniProtKB=G3SK70	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000014541.4\|UniProtKB=A0A5F7ZN66	Macaca mulatta	O
MOUSE\|MGI=MGI=1859388\|UniProtKB=Q9JI71	Mus musculus	O
RAT\|RGD=1309740\|UniProtKB=D3ZHH1	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000010361.4\|UniProtKB=Q0V7L8	Bos taurus	O
PIG\|Ensembl=ENSSSCG00005017001.1\|UniProtKB=A0A4X1URL1	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000013434.3\|UniProtKB=A0A9L0SLB3	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000014721.6\|UniProtKB=M3WL78	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845029137.1\|UniProtKB=A0A8I3Q0Q1	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000000198.4\|UniProtKB=A0A5F8G283	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000012601.3\|UniProtKB=F7G4X4	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010022311.1\|UniProtKB=A0A8V0ZHH9	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000003483.4\|UniProtKB=H9G7L9	Anolis carolinensis	O
XENLA\|Gene=LOC108705808\|UniProtKB=A0A8J1LM50	Xenopus laevis	O
ORYLA\|Ensembl=ENSORLG00000016743.2\|UniProtKB=H2MQC7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000018020.2\|UniProtKB=A0A3B3I4U3	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-041014-73\|UniProtKB=Q1ECY3	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000012287.1\|UniProtKB=W5N3B4	lepisosteus oculatus	O
HUMAN\|HGNC=2908\|UniProtKB=O00548	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000018824.5\|UniProtKB=A0A2J8JA34	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000005504.3\|UniProtKB=G3QRX5	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000021144.4\|UniProtKB=F7HB47	Macaca mulatta	O
MOUSE\|MGI=MGI=104659\|UniProtKB=Q61483	Mus musculus	O
RAT\|RGD=70949\|UniProtKB=P97677	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000031476.4\|UniProtKB=A0A3Q1MAU6	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000027726.4\|UniProtKB=I3LNT3	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000014357.3\|UniProtKB=A0A9L0TK17	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000004661.5\|UniProtKB=A0A5F5XZN3	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845022293.1\|UniProtKB=A0A8I3S5K2	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000005607.3\|UniProtKB=A0A5F8GQ05	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000015029.3\|UniProtKB=A0A6I8P7V2	Ornithorhynchus anatinus	O
ANOCA\|Ensembl=ENSACAG00000002704.4\|UniProtKB=A0A803T388	Anolis carolinensis	O
ORYLA\|Ensembl=ENSORLG00000010606.2\|UniProtKB=A0A3B3IHD2	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000027625.1\|UniProtKB=A0A3B3HAC3	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-990415-47\|UniProtKB=Q8UWJ4	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-980526-29\|UniProtKB=Q6DI48	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000015493.1\|UniProtKB=W5NEK8	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000004194.3\|UniProtKB=F7ALL8	Ciona intestinalis	O
BRAFL\|Gene=LOC118417211\|UniProtKB=A0A9J7LBM6	Branchiostoma floridae	O
CAEEL\|WormBase=WBGene00015328\|UniProtKB=O44443	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG19989\|UniProtKB=A8XWV9	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG19981\|UniProtKB=A8XWV4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00106762\|UniProtKB=A0A2A6CBX6	Pristionchus pacificus	O
CAEBR\|WormBase=WBGene00031967\|UniProtKB=A8XBI4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00275663\|UniProtKB=A0A2A6BU86	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00095068\|UniProtKB=A0A2A6BLX6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00097058\|UniProtKB=A0A2A6BDF7	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00003001\|UniProtKB=P14585	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG06809\|UniProtKB=A8X345	Caenorhabditis briggsae	O
IXOSC\|EnsemblGenome=ISCW020634\|UniProtKB=B7Q2M9	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g216602\|UniProtKB=A7SS38	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g128497\|UniProtKB=A7SR75	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_38707\|UniProtKB=A9V9N1	Monosiga brevicollis	O
GIAIC\|EnsemblGenome=GL50803_24512\|UniProtKB=A8B4D5	Giardia intestinalis	O
CHLRE\|EnsemblGenome=CHLRE_16g690095v5\|UniProtKB=A0A2K3CW78	Chlamydomonas reinhardtii	O