PANTHER Gene Information

Gene Symbol(s):

DLL4

Organism:

lepisosteus oculatus

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Gene Name:

Delta-like protein

Gene ID:

ENSLOCG00000012287.1

Protein ID:

W5N3B4

Persistent Id:

PTN002779059

Alternate Ids:

W5N3B4_LEPOC(UniProtKB-ID)	ENSLOCT00000015152(Ensembl_TRS)
W5N3B4(Synonym)	ENSLOCG00000012287(Ensembl)
ENSLOCP00000015123(Ensembl_PRO)	AHAT01019065(EMBL)
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PANTHER Classification

PANTHER Family:	NOTCH LIGAND FAMILY MEMBER (PTHR24044)
PANTHER Subfamily:	DELTA-LIKE PROTEIN 4 (PTHR24044:SF320)
PANTHER GO-slim Molecular Function:	signaling receptor binding
PANTHER GO-slim Biological Process:	negative regulation of Notch signaling pathway Notch signaling pathway
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	intercellular signal molecule

Pathway Categories:

Angiogenesis

Delta

Notch signaling pathway

Delta

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	calcium ion binding, Notch binding
GO BP Complete:	Notch signaling pathway, cell communication, nervous system development, animal organ development, negative regulation of Notch signaling pathway
GO CC Complete:	membrane, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=2910\|UniProtKB=Q9NR61	Homo sapiens	LDO
GORGO\|Ensembl=ENSGGOG00000028605.2\|UniProtKB=G3SK70	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000014541.4\|UniProtKB=A0A5F7ZN66	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1859388\|UniProtKB=Q9JI71	Mus musculus	LDO
RAT\|RGD=1309740\|UniProtKB=D3ZHH1	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000010361.4\|UniProtKB=Q0V7L8	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00005017001.1\|UniProtKB=A0A4X1URL1	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000013434.3\|UniProtKB=A0A9L0SLB3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000014721.6\|UniProtKB=M3WL78	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845029137.1\|UniProtKB=A0A8I3Q0Q1	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000000198.4\|UniProtKB=A0A5F8G283	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000012601.3\|UniProtKB=F7G4X4	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010022311.1\|UniProtKB=A0A8V0ZHH9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000003483.4\|UniProtKB=H9G7L9	Anolis carolinensis	LDO
XENLA\|Gene=LOC108705808\|UniProtKB=A0A8J1LM50	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000016743.2\|UniProtKB=H2MQC7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000018020.2\|UniProtKB=A0A3B3I4U3	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-041014-73\|UniProtKB=Q1ECY3	Danio rerio	LDO
CIOIN\|Ensembl=ENSCING00000004194.3\|UniProtKB=F7ALL8	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118417211\|UniProtKB=A0A9J7LBM6	Branchiostoma floridae	LDO
CAEEL\|WormBase=WBGene00015328\|UniProtKB=O44443	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG19989\|UniProtKB=A8XWV9	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG19981\|UniProtKB=A8XWV4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00106762\|UniProtKB=A0A2A6CBX6	Pristionchus pacificus	O
CAEBR\|WormBase=WBGene00031967\|UniProtKB=A8XBI4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00275663\|UniProtKB=A0A2A6BU86	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00095068\|UniProtKB=A0A2A6BLX6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00097058\|UniProtKB=A0A2A6BDF7	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00003001\|UniProtKB=P14585	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG06809\|UniProtKB=A8X345	Caenorhabditis briggsae	O
IXOSC\|EnsemblGenome=ISCW020634\|UniProtKB=B7Q2M9	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG80798\|UniProtKB=T1G456	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG133373\|UniProtKB=T1EI04	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG85694\|UniProtKB=T1G618	helobdella robusta	O
DROME\|FlyBase=FBgn0021742\|UniProtKB=Q9VZ44	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP010940\|UniProtKB=A0A1S4H5C2	Anopheles gambiae	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_39669\|UniProtKB=E9FR30	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_323318\|UniProtKB=E9GYJ2	Daphnia pulex	O
DROME\|FlyBase=FBgn0000463\|UniProtKB=P10041	Drosophila melanogaster	LDO
TRICA\|EnsemblGenome=TC004114\|UniProtKB=D6W6S0	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_63051\|UniProtKB=E9HI96	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW013622\|UniProtKB=B7QHQ8	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG77153\|UniProtKB=T1G2T6	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g216602\|UniProtKB=A7SS38	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g128497\|UniProtKB=A7SR75	Nematostella vectensis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_38707\|UniProtKB=A9V9N1	Monosiga brevicollis	O
GIAIC\|EnsemblGenome=GL50803_24512\|UniProtKB=A8B4D5	Giardia intestinalis	O
CHLRE\|EnsemblGenome=CHLRE_16g690095v5\|UniProtKB=A0A2K3CW78	Chlamydomonas reinhardtii	O