PANTHER Gene Information

Gene Symbol(s):

dld

Organism:

Danio rerio

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Gene Name:

Delta-like protein D

Gene ID:

ZDB-GENE-990415-47

Protein ID:

Q8UWJ4

Persistent Id:

PTN000621410

Alternate Ids:

CAA72425(EMBL-CDS)	Y11760(EMBL)
aei(Synonym)	68565528(GI)
P87357(AltAccession)	ZDB-GENE-990415-47(ZFIN)
dld(Symbol)	DLLD_DANRE(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	NOTCH LIGAND FAMILY MEMBER (PTHR24044)
PANTHER Subfamily:	DELTA-LIKE PROTEIN 1 (PTHR24044:SF380)
PANTHER GO-slim Molecular Function:	signaling receptor binding
PANTHER GO-slim Biological Process:	negative regulation of Notch signaling pathway Notch signaling pathway
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	intercellular signal molecule

Pathway Categories:

Angiogenesis

Delta

Notch signaling pathway

Delta

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	protein binding, calcium ion binding, PDZ domain binding, Notch binding
GO BP Complete:	sclerotome development, cilium assembly, cell communication, regulation of hematopoietic stem cell differentiation, determination of left/right asymmetry in lateral mesoderm, nervous system development, anterior/posterior pattern specification, somatic motor neuron differentiation, hematopoietic stem cell differentiation, digestive tract morphogenesis, ventral spinal cord interneuron differentiation, negative regulation of Notch signaling pathway, hematopoietic progenitor cell differentiation, determination of left/right symmetry, Notch signaling pathway, system development, somitogenesis, lateral inhibition, cell differentiation, determination of liver left/right asymmetry, determination of pancreatic left/right asymmetry
GO CC Complete:	perinuclear region of cytoplasm, cytoplasm, membrane, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=2908\|UniProtKB=O00548	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000018824.5\|UniProtKB=A0A2J8JA34	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000005504.3\|UniProtKB=G3QRX5	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000021144.4\|UniProtKB=F7HB47	Macaca mulatta	O
MOUSE\|MGI=MGI=104659\|UniProtKB=Q61483	Mus musculus	O
RAT\|RGD=70949\|UniProtKB=P97677	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000031476.4\|UniProtKB=A0A3Q1MAU6	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000027726.4\|UniProtKB=I3LNT3	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000014357.3\|UniProtKB=A0A9L0TK17	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000004661.5\|UniProtKB=A0A5F5XZN3	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845022293.1\|UniProtKB=A0A8I3S5K2	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000005607.3\|UniProtKB=A0A5F8GQ05	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000015029.3\|UniProtKB=A0A6I8P7V2	Ornithorhynchus anatinus	O
ANOCA\|Ensembl=ENSACAG00000002704.4\|UniProtKB=A0A803T388	Anolis carolinensis	O
ORYLA\|Ensembl=ENSORLG00000010606.2\|UniProtKB=A0A3B3IHD2	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000027625.1\|UniProtKB=A0A3B3HAC3	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000015493.1\|UniProtKB=W5NEK8	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000004194.3\|UniProtKB=F7ALL8	Ciona intestinalis	O
BRAFL\|Gene=LOC118417211\|UniProtKB=A0A9J7LBM6	Branchiostoma floridae	O
CAEEL\|WormBase=WBGene00015328\|UniProtKB=O44443	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG19989\|UniProtKB=A8XWV9	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG19981\|UniProtKB=A8XWV4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00106762\|UniProtKB=A0A2A6CBX6	Pristionchus pacificus	O
CAEBR\|WormBase=WBGene00031967\|UniProtKB=A8XBI4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00275663\|UniProtKB=A0A2A6BU86	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00095068\|UniProtKB=A0A2A6BLX6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00097058\|UniProtKB=A0A2A6BDF7	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00003001\|UniProtKB=P14585	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG06809\|UniProtKB=A8X345	Caenorhabditis briggsae	O
IXOSC\|EnsemblGenome=ISCW020634\|UniProtKB=B7Q2M9	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG80798\|UniProtKB=T1G456	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG133373\|UniProtKB=T1EI04	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG85694\|UniProtKB=T1G618	helobdella robusta	O
DROME\|FlyBase=FBgn0021742\|UniProtKB=Q9VZ44	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP010940\|UniProtKB=A0A1S4H5C2	Anopheles gambiae	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_39669\|UniProtKB=E9FR30	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_323318\|UniProtKB=E9GYJ2	Daphnia pulex	O
DROME\|FlyBase=FBgn0000463\|UniProtKB=P10041	Drosophila melanogaster	O
TRICA\|EnsemblGenome=TC004114\|UniProtKB=D6W6S0	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_63051\|UniProtKB=E9HI96	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW013622\|UniProtKB=B7QHQ8	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG77153\|UniProtKB=T1G2T6	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g216602\|UniProtKB=A7SS38	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g128497\|UniProtKB=A7SR75	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_38707\|UniProtKB=A9V9N1	Monosiga brevicollis	O
GIAIC\|EnsemblGenome=GL50803_24512\|UniProtKB=A8B4D5	Giardia intestinalis	O
CHLRE\|EnsemblGenome=CHLRE_16g690095v5\|UniProtKB=A0A2K3CW78	Chlamydomonas reinhardtii	O