PANTHER Gene Information

Gene Symbol(s):

ALK

Organism:

Canis lupus familiaris

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Gene Name:

ALK tyrosine kinase receptor

Gene ID:

ENSCAFG00845011603

Protein ID:

P0DV84

Persistent Id:

PTN001562083

Alternate Ids:

ALK_CANLF(UniProtKB-ID)	ENSCAFP00845016222(Ensembl_PRO)
2.7.10.1 {ECO:0000250\|UniProtKB:Q9UM73}(EC)	XM_540136(refSeq)
ENSCAFG00845011603(Ensembl)	345781961(GI)
ALK(Synonym)	AAEX03010811(EMBL)
ALK{ECO:0000303\|PubMed:25605972}(Symbol)	ENSCAFT00845020686(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	TYROSINE-PROTEIN KINASE RECEPTOR (PTHR24416)
PANTHER Subfamily:	ALK TYROSINE KINASE RECEPTOR (PTHR24416:SF276)
PANTHER GO-slim Molecular Function:	transmembrane receptor protein tyrosine kinase activity
PANTHER GO-slim Biological Process:	positive regulation of kinase activity transmembrane receptor protein tyrosine kinase signaling pathway regulation of neuron differentiation regulation of cell population proliferation multicellular organism development
PANTHER GO-slim Cellular Component:	receptor complex plasma membrane
PANTHER protein class:	transmembrane signal receptor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ATP binding, transmembrane receptor protein tyrosine kinase activity
GO BP Complete:	multicellular organism development, cell surface receptor protein tyrosine kinase signaling pathway, positive regulation of kinase activity, regulation of neuron differentiation, regulation of cell population proliferation
GO CC Complete:	receptor complex, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=427\|UniProtKB=Q9UM73	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000011796.6\|UniProtKB=H2QHP7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000004378.3\|UniProtKB=G3QP17	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000010265.4\|UniProtKB=F6PVR5	Macaca mulatta	LDO
MOUSE\|MGI=MGI=103305\|UniProtKB=P97793	Mus musculus	LDO
RAT\|RGD=628622\|UniProtKB=F1LRZ0	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000007379.7\|UniProtKB=A0A3Q1MKW9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000044640.2\|UniProtKB=A0A5G2RBJ3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000007080.4\|UniProtKB=F7DDR7	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000042185.2\|UniProtKB=A0A337SD59	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000015531.5\|UniProtKB=F6VHJ5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000014473.3\|UniProtKB=F6X759	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010022572.1\|UniProtKB=A0A8V0ZP30	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000013890.3\|UniProtKB=G1KPC7	Anolis carolinensis	O
CHICK\|Ensembl=ENSGALG00010017563.1\|UniProtKB=A0A8V0Z3S3	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000008958.4\|UniProtKB=A0A803T8L6	Anolis carolinensis	LDO
XENLA\|Gene=LOC108699739\|UniProtKB=A0A1L8EZT5	Xenopus laevis	O
XENLA\|Gene=LOC108698980\|UniProtKB=A0A8J0TIV8	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000000055\|UniProtKB=F6UBP5	Xenopus tropicalis	O
XENLA\|Gene=LOC108717382\|UniProtKB=A0A8J1KS75	Xenopus laevis	O
XENLA\|Gene=LOC108716096\|UniProtKB=A0A8J1KNP1	Xenopus laevis	LDO
XENTR\|Gene=alk\|UniProtKB=A0A8J1JM32	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000015434.2\|UniProtKB=H2MKV3	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030616-115\|UniProtKB=F1QVU0	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000014716.1\|UniProtKB=W5NBY0	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000022549.1\|UniProtKB=A0A3B3HYV3	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-031027-1\|UniProtKB=F8W3R9	Danio rerio	LDO
BRAFL\|Gene=LOC118415382\|UniProtKB=A0A9J7MQY2	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC587032\|UniProtKB=A0A7M7T3B4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105441992\|UniProtKB=A0A7M7PPG6	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC574978\|UniProtKB=A0A7M7N7T2	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00004740\|UniProtKB=O76411	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG18982\|UniProtKB=A8XUH7	Caenorhabditis briggsae	LDO
DROME\|FlyBase=FBgn0040505\|UniProtKB=Q7KJ08	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP012070\|UniProtKB=A0A453YYL0	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC002114\|UniProtKB=D6WGT3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_309238\|UniProtKB=E9HB47	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_187767\|UniProtKB=E9G7E5	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW000831\|UniProtKB=B7P3J2	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG164816\|UniProtKB=T1EVU6	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g85808\|UniProtKB=A7RLS3	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG4397\|UniProtKB=B3RT13	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG12208\|UniProtKB=B3RT14	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG22855\|UniProtKB=B3RT16	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_25143\|UniProtKB=A9UYJ2	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_7936\|UniProtKB=A9UYJ1	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_37833\|UniProtKB=A9V451	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_12183\|UniProtKB=A9VBG8	Monosiga brevicollis	O