PANTHER Gene Information   
Gene Symbol(s): EIF4A3
Organism: Canis lupus familiaris
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Gene Name: Eukaryotic translation initiation factor 4A3
Gene ID: ENSCAFG00845013343.1
Protein ID: A0A8I3NS82
Persistent Id: PTN002777836
Alternate Ids:
A0A8I3NS82(Synonym) XP_533130(refSeq)
73964736(GI) ENSCAFG00845013343(Ensembl)
475922(GeneID) ENSCAFT00845023772(Ensembl_TRS)
A0A8I3NS82_CANLF(UniProtKB-ID) ENSCAFP00845018656(Ensembl_PRO)
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PANTHER Classification
PANTHER Family: ATP-DEPENDENT RNA HELICASE DBP3 (PTHR47958)
PANTHER Subfamily: EUKARYOTIC INITIATION FACTOR 4A-III (PTHR47958:SF26)  
PANTHER GO-slim Molecular Function: helicase activity
mRNA binding
catalytic activity, acting on RNA
PANTHER GO-slim Biological Process: mRNA splicing, via spliceosome
PANTHER GO-slim Cellular Component: nucleolus
catalytic step 2 spliceosome
PANTHER protein class: RNA helicase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ATP binding, RNA helicase activity, poly(A) binding, mRNA binding, hydrolase activity
GO BP Complete: positive regulation of translation, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, embryonic cranial skeleton morphogenesis, regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, rRNA processing, negative regulation of translation, mRNA transport, mRNA splicing, via spliceosome
GO CC Complete: exon-exon junction complex, catalytic step 2 spliceosome, cytoplasm, nuclear speck, U2-type catalytic step 1 spliceosome, nucleolus
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Gene expression (Transcription), mRNA Splicing, mRNA 3'-end processing, Nonsense-Mediated Decay (NMD), mRNA Splicing - Major Pathway, Transport of Mature Transcript to Cytoplasm, Deadenylation-dependent mRNA decay, Deadenylation of mRNA, RNA Polymerase II Transcription Termination, Processing of Capped Intron-Containing Pre-mRNA, Immune System, Cytokine Signaling in Immune system, Metabolism of RNA, ISG15 antiviral mechanism, RNA Polymerase II Transcription, Transport of Mature mRNA derived from an Intron-Containing Transcript, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC), Interferon Signaling, Antiviral mechanism by IFN-stimulated genes

Orthologs