PANTHER Gene Information   
Gene Symbol(s): EIF4A3
Organism: Gallus gallus
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Gene Name: Eukaryotic initiation factor 4A-III
Gene ID: ENSGALG00010016961
Protein ID: Q5ZM36
Persistent Id: PTN002777842
Alternate Ids:
ENSGALP00015008760(Ensembl_PRO) 416704(GeneID)
EIF4A3(Symbol) eIF-4A-III(Synonym)
AJ719548(EMBL) ENSGALT00015015783(Ensembl_TRS)
ENSGALG00010016961(Ensembl) CAG31207(EMBL-CDS)
3.6.4.13 {ECO:0000250|UniProtKB:P38919}(EC) 53127756(GI)
IF4A3_CHICK(UniProtKB-ID) NP_001025820(refSeq)
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PANTHER Classification
PANTHER Family: ATP-DEPENDENT RNA HELICASE DBP3 (PTHR47958)
PANTHER Subfamily: EUKARYOTIC INITIATION FACTOR 4A-III (PTHR47958:SF26)  
PANTHER GO-slim Molecular Function: helicase activity
mRNA binding
catalytic activity, acting on RNA
PANTHER GO-slim Biological Process: mRNA splicing, via spliceosome
PANTHER GO-slim Cellular Component: nucleolus
catalytic step 2 spliceosome
PANTHER protein class: RNA helicase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ATP hydrolysis activity, ATP binding, DNA clamp loader activity, ATP-dependent H2AZ histone chaperone activity, RNA helicase activity, mRNA binding, ATP-dependent H3-H4 histone complex chaperone activity, cohesin loader activity, chromatin extrusion motor activity
GO BP Complete: regulation of translation, chromatin remodeling, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of alternative mRNA splicing, via spliceosome, chromatin looping, mRNA transport, mRNA splicing, via spliceosome
GO CC Complete: nucleus, catalytic step 2 spliceosome, cytoplasm, nuclear speck, U2-type catalytic step 1 spliceosome, nucleolus
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: RNA Polymerase II Transcription Termination, RNA Polymerase II Transcription, Transport of Mature Transcript to Cytoplasm, Processing of Capped Intron-Containing Pre-mRNA, Metabolism of RNA, ISG15 antiviral mechanism, Deadenylation-dependent mRNA decay, Deadenylation of mRNA, Immune System, Gene expression (Transcription), Nonsense-Mediated Decay (NMD), Cytokine Signaling in Immune system, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC), mRNA 3'-end processing, Interferon Signaling, Transport of Mature mRNA derived from an Intron-Containing Transcript, Antiviral mechanism by IFN-stimulated genes

Orthologs