PANTHER Gene Information

Gene Symbol(s):

EIF4A3

Organism:

Equus caballus

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Tree

Gene Name:

RNA helicase

Gene ID:

ENSECAG00000015925.4

Protein ID:

A0A9L0RU62

Persistent Id:

PTN009217332

Alternate Ids:

ENSECAG00000015925(Ensembl)	ENSECAT00000098702(Ensembl_TRS)
A0A9L0RU62_HORSE(UniProtKB-ID)	ENSECAP00000065392(Ensembl_PRO)
A0A9L0RU62(Synonym)
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PANTHER Classification

PANTHER Family:	ATP-DEPENDENT RNA HELICASE DBP3 (PTHR47958)
PANTHER Subfamily:	EUKARYOTIC INITIATION FACTOR 4A-III (PTHR47958:SF26)
PANTHER GO-slim Molecular Function:	helicase activity mRNA binding catalytic activity, acting on RNA
PANTHER GO-slim Biological Process:	mRNA splicing, via spliceosome
PANTHER GO-slim Cellular Component:	nucleolus catalytic step 2 spliceosome
PANTHER protein class:	RNA helicase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	nucleic acid binding, ATP binding, RNA helicase activity, poly(A) binding, mRNA binding, helicase activity, hydrolase activity
GO BP Complete:	RNA splicing, positive regulation of translation, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, embryonic cranial skeleton morphogenesis, regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, rRNA processing, negative regulation of translation, mRNA transport, mRNA splicing, via spliceosome
GO CC Complete:	nucleus, exon-exon junction complex, catalytic step 2 spliceosome, cytoplasm, nuclear speck, U2-type catalytic step 1 spliceosome, spliceosomal complex, nucleolus, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=18683\|UniProtKB=P38919	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000009737.6\|UniProtKB=A0A2I3RG70	Pan troglodytes	LDO
MACMU\|Ensembl=ENSMMUG00000009590.3\|UniProtKB=H9Z1T8	Macaca mulatta	LDO
MOUSE\|MGI=MGI=3646594\|UniProtKB=A0A0N4SVP8	Mus musculus	O
MOUSE\|MGI=MGI=3644226\|UniProtKB=E9PV04	Mus musculus	O
MOUSE\|MGI=MGI=1923731\|UniProtKB=Q91VC3	Mus musculus	LDO
RAT\|RGD=1591139\|UniProtKB=Q3B8Q2	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000016023\|UniProtKB=Q2NL22	Bos taurus	LDO
FELCA\|Ensembl=ENSFCAG00000008246.6\|UniProtKB=M3W982	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845013343.1\|UniProtKB=A0A8I3NS82	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000003697.2\|UniProtKB=F7F5D3	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000002190.3\|UniProtKB=F7GE48	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000000334.4\|UniProtKB=F7E862	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010016961\|UniProtKB=Q5ZM36	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000014384.4\|UniProtKB=G1KPX6	Anolis carolinensis	LDO
XENLA\|Gene=eif4a3-a\|UniProtKB=Q5U526	Xenopus laevis	O
XENLA\|Gene=eif4a3-b\|UniProtKB=O42226	Xenopus laevis	O
XENLA\|Gene=LOC121393038\|UniProtKB=A0A8J1KU59	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5773453\|UniProtKB=B7ZTW1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000018405.2\|UniProtKB=A0A3B3I8I5	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-915\|UniProtKB=Q7ZVA6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000015796.1\|UniProtKB=W5NFP2	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000007818.3\|UniProtKB=F6XF93	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_123431\|UniProtKB=C3ZMT4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC580266\|UniProtKB=A0A7M7T507	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00018007\|UniProtKB=O44781	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00022029\|UniProtKB=Q9BL61	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00026766\|UniProtKB=A8WW00	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00027664\|UniProtKB=A8WZ62	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00304441\|UniProtKB=A0A8R1Z2Q8	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0037573\|UniProtKB=Q9VHS8	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP003089\|UniProtKB=Q7PQQ2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC009998\|UniProtKB=D6WR65	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_104930\|UniProtKB=E9GNU3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_300157\|UniProtKB=E9FRB0	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW013399\|UniProtKB=B7QER9	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG156498\|UniProtKB=T1ELX6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG98421\|UniProtKB=T1G9M6	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g236387\|UniProtKB=A7RIU5	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG38398\|UniProtKB=B3SAG4	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_21732\|UniProtKB=A9VB75	Monosiga brevicollis	LDO
YEAST\|SGD=S000002428\|UniProtKB=Q12099	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AER408W\|UniProtKB=Q755W0	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000189056\|UniProtKB=Q5A9Z6	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F02695g\|UniProtKB=Q6C347	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_08016\|UniProtKB=Q5AUL4	Emericella nidulans	LDO
ASPFU\|Gene_ORFName=AFUA_5G02410\|UniProtKB=Q4WEB4	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU01234\|UniProtKB=Q9P735	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_06435\|UniProtKB=A7EM88	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_11134\|UniProtKB=Q0UAT0	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC1F5.10\|UniProtKB=Q10055	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02879\|UniProtKB=B6K1F4	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNC06360\|UniProtKB=P0CQ72	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_06129\|UniProtKB=Q4P184	Ustilago maydis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_13234\|UniProtKB=F4P8T7	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_106300\|UniProtKB=C4M394	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0269192\|UniProtKB=Q55D61	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_156303\|UniProtKB=F0ZW88	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_28_1530\|UniProtKB=Q4Q8B2	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.12.0011\|UniProtKB=Q384F2	Trypanosoma brucei	LDO
PLAF7\|EnsemblGenome=PF3D7_0422700\|UniProtKB=Q8IFN9	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00028099001\|UniProtKB=A0BEU9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00029794001\|UniProtKB=A0BKU6	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_354\|UniProtKB=B8BW92	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GA17_PHYRM\|UniProtKB=H3GA17	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_03g199647v5\|UniProtKB=A0A2K3DZM1	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00029p00094300\|UniProtKB=W1PP00	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_117G00670\|UniProtKB=A0A0K9Q248	Zostera marina	LDO
ZOSMR\|Gene_ORFName=ZOSMA_66G00150\|UniProtKB=A0A0K9NS45	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma03_g28240\|UniProtKB=A0A804IH84	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma09_g24280\|UniProtKB=A0A804KN63	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_017376mg\|UniProtKB=K3YSY1	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G356900\|UniProtKB=C5XWR4	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb259470\|UniProtKB=A0A0B4J3A7	Zea mays	LDO
MAIZE\|EnsemblGenome=Zm00001eb190630\|UniProtKB=Q2MJJ9	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os03g0566800\|UniProtKB=Q10I26	Oryza sativa	LDO
ORYSJ\|EnsemblGenome=Os01g0639100\|UniProtKB=Q5VNM3	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g60590v3\|UniProtKB=I1IFR0	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0210840\|UniProtKB=A0A8I6X045	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS2D02G554300\|UniProtKB=A0A3B6DNP9	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2A02G552800\|UniProtKB=A0A3B6B9E6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2D02G553400\|UniProtKB=A0A3B6DMQ9	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2B02G584200\|UniProtKB=A0A3B6CIK2	Triticum aestivum	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0633530\|UniProtKB=F2DJI3	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6A02G416700\|UniProtKB=A0A3B6NYF7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6B02G472700\|UniProtKB=A0A3B6PW49	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS6D02G401900\|UniProtKB=A0A3B6QPU4	Triticum aestivum	LDO
NELNU\|Gene=LOC104587558\|UniProtKB=A0A1U7YZA1	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110800971\|UniProtKB=A0A9R0J6V0	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HanXRQr2_Chr06g0248661\|UniProtKB=A0A9K3IR65	Helianthus annuus	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr17g0789121\|UniProtKB=A0A251UHB0	Helianthus annuus	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a007337mg\|UniProtKB=A0A022QNH3	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a007807mg\|UniProtKB=A0A022RZP0	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a007340mg\|UniProtKB=A0A022RBU3	Erythranthe guttata	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400007646\|UniProtKB=M1ACK8	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc11g033280.2\|UniProtKB=A0A3Q7IVC4	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107779209\|UniProtKB=A0A1S3YSD8	Nicotiana tabacum	O
TOBAC\|Gene=LOC107770285\|UniProtKB=A0A1S3XYU0	Nicotiana tabacum	LDO
VITVI\|Gene_OrderedLocusName=VIT_06s0080g00550\|UniProtKB=F6HHF5	Vitis vinifera	LDO
BRANA\|Gene_ORFName=DARMORV10_C05P31380.1\|UniProtKB=A0A078GC12	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A08P03010.1\|UniProtKB=A0A078J6R0	Brassica napus	O
BRACM\|EnsemblGenome=Bra014267\|UniProtKB=A0A397Y762	Brassica campestris	O
ARATH\|TAIR=locus=2008296\|UniProtKB=Q9C8J1	Arabidopsis thaliana	O
BRANA\|Gene_ORFName=DARMORV10_C03P50590.1\|UniProtKB=A0A078GC55	Brassica napus	O
BRACM\|EnsemblGenome=Bra032127\|UniProtKB=A0A398A9F5	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_A01P34950.1\|UniProtKB=A0A078HUL6	Brassica napus	O
BRACM\|EnsemblGenome=Bra038231\|UniProtKB=M4FAW6	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_C05P45030.1\|UniProtKB=A0A078GHI2	Brassica napus	LDO
BRANA\|Gene_ORFName=DARMORV10_C01P44360.1\|UniProtKB=A0A078H6B7	Brassica napus	LDO
BRANA\|Gene_ORFName=DARMORV10_A05P29840.1\|UniProtKB=A0A078IP32	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra022449\|UniProtKB=A0A397ZC25	Brassica campestris	LDO
ARATH\|TAIR=locus=2091191\|UniProtKB=Q94A52	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107947377\|UniProtKB=A0A1U8NES7	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107937597\|UniProtKB=A0A1U8MGT2	Gossypium hirsutum	O
GOSHI\|Gene=LOC107900113\|UniProtKB=A0A1U8IZD1	Gossypium hirsutum	O
GOSHI\|Gene=LOC107928882\|UniProtKB=A0A1U8LQD1	Gossypium hirsutum	O
GOSHI\|Gene=LOC107920423\|UniProtKB=A0A1U8KT43	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107946114\|UniProtKB=A0A1U8NCY6	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_007746\|UniProtKB=A0A061EA73	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g015454mg\|UniProtKB=A0A067EP48	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_007G070000v3\|UniProtKB=B9HGS9	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_005G093900v3\|UniProtKB=A0A2K2AE38	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_11G102100\|UniProtKB=A0A2C9V034	Manihot esculenta	LDO
MANES\|EnsemblGenome=MANES_04G061200\|UniProtKB=A0A2C9W2H3	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0807900\|UniProtKB=B9S4I6	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_15G158800\|UniProtKB=A0A0R0GBB6	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_09G052500\|UniProtKB=I1L171	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_2g438110\|UniProtKB=A0A072V6Z3	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr13_03930\|UniProtKB=A0A2I4DZS6	Juglans regia	O
JUGRE\|EnsemblGenome=Jr16_20430\|UniProtKB=A0A2I4F5E0	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G654480\|UniProtKB=A0A0A0L9P0	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_3G165200\|UniProtKB=M5WSL3	Prunus persica	O
PRUPE\|EnsemblGenome=PRUPE_1G346100\|UniProtKB=M5XD05	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_425794\|UniProtKB=D8SUB6	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_411827\|UniProtKB=D8RJ57	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_441388\|UniProtKB=D8RJ55	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_411829\|UniProtKB=D8RJ60	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_403535\|UniProtKB=D8QRQ7	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_164382\|UniProtKB=D8QNK4	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c22_4200\|UniProtKB=A0A7I4CLT6	Physcomitrella patens	LDO
PHYPA\|EnsemblGenome=Pp3c21_9040\|UniProtKB=A0A2K1IR91	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c19_19960\|UniProtKB=A0A2K1IZ38	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0112s0059\|UniProtKB=A0A2R6WC58	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000140100\|UniProtKB=A0A1Y1HNC9	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_1182\|UniProtKB=A9A5S3	Nitrosopumilus maritimus	O
SACS2\|EnsemblGenome=SSO2036\|UniProtKB=Q97WT0	Sulfolobus solfataricus	O
SACS2\|EnsemblGenome=SSO1889\|UniProtKB=Q97X64	Sulfolobus solfataricus	O