PANTHER Gene Information

Gene Symbol(s):

EPS15

Organism:

Canis lupus familiaris

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Gene Name:

Epidermal growth factor receptor pathway substrate 15

Gene ID:

ENSCAFG00845022599.1

Protein ID:

A0A8I3PMU1

Persistent Id:

PTN001342506

Alternate Ids:

ENSCAFT00845041017(Ensembl_TRS)	A0A8I3PMU1(Synonym)
A0A8I3PMU1_CANLF(UniProtKB-ID)	ENSCAFG00845022599(Ensembl)
ENSCAFP00845032135(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	EH DOMAIN (PTHR11216)
PANTHER Subfamily:	EPIDERMAL GROWTH FACTOR RECEPTOR SUBSTRATE 15 (PTHR11216:SF54)
PANTHER GO-slim Molecular Function:	cell adhesion molecule binding
PANTHER GO-slim Biological Process:	endosomal transport endocytosis
PANTHER GO-slim Cellular Component:	membrane coat plasma membrane protein complex clathrin-coated pit
PANTHER protein class:	membrane traffic protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	polyubiquitin modification-dependent protein binding, calcium ion binding
GO BP Complete:	receptor-mediated endocytosis of virus by host cell, clathrin coat assembly, endosomal transport, endocytosis, Golgi to endosome transport
GO CC Complete:	cytoplasm, intracellular membrane-bounded organelle, clathrin coat of coated pit, cytosol, aggresome, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Signal Transduction, Membrane Trafficking, Signaling by Receptor Tyrosine Kinases, Signaling by MET, Clathrin-mediated endocytosis, Negative regulation of MET activity, Signaling by EGFR, Cargo recognition for clathrin-mediated endocytosis, Vesicle-mediated transport, EGFR downregulation

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3419\|UniProtKB=P42566	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000000729.7\|UniProtKB=H2PZ06	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000006160.3\|UniProtKB=G3SBN0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000012055.4\|UniProtKB=A0A1D5QSC4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=104583\|UniProtKB=P42567	Mus musculus	LDO
RAT\|RGD=1305550\|UniProtKB=A0A8I5YC99	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000005542.6\|UniProtKB=A5D7I1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000003872.5\|UniProtKB=A0A5G2QFX7	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000020824.4\|UniProtKB=F6WFQ1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000027650.4\|UniProtKB=A0A5F5XD12	Felis catus	LDO
CHICK\|Ensembl=ENSGALG00010024596.1\|UniProtKB=A0A8V0ZYI9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000007433.4\|UniProtKB=G1KGR7	Anolis carolinensis	LDO
XENLA\|Gene=eps15.S\|UniProtKB=A0A8J0V6Y6	Xenopus laevis	O
XENLA\|Gene=eps15.L\|UniProtKB=A0A8J0V262	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-6070905\|UniProtKB=A0A8J0Q9H0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000017166.2\|UniProtKB=H2MRU8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-081104-264\|UniProtKB=F1QIJ6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000009453.1\|UniProtKB=W5MT32	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000009283.3\|UniProtKB=F7BA39	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118414009\|UniProtKB=A0A9J7L012	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC583813\|UniProtKB=A0A7M7PLS9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC576532\|UniProtKB=A0A7M7PGF0	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00001224\|UniProtKB=Q9BIF4	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00025548\|UniProtKB=A8WU59	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00097714\|UniProtKB=A0A2A6BZ40	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0035060\|UniProtKB=Q9W111	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP009189\|UniProtKB=A0A1S4H0E4	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC015931\|UniProtKB=D6WTU9	Tribolium castaneum	LDO
HELRO\|EnsemblGenome=HelroG189047\|UniProtKB=T1FQL2	helobdella robusta	LDO
TRIAD\|EnsemblGenome=TriadG58856\|UniProtKB=B3S3V2	Trichoplax adhaerens	LDO
EREGS\|EnsemblGenome=AGOS_AFR103W\|UniProtKB=Q754G7	Eremothecium gossypii	O
CANAL\|CGD=CAL0000177117\|UniProtKB=Q59SR6	Candida albicans	O
ENTH1\|EnsemblGenome=CL6EHI_010300\|UniProtKB=C4LYS7	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_189890\|UniProtKB=C4M720	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0287325\|UniProtKB=Q54KI4	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_148600\|UniProtKB=F0ZBJ2	Dictyostelium purpureum	O
PLAF7\|EnsemblGenome=PF3D7_0322600\|UniProtKB=O97322	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1025000\|UniProtKB=Q8IJF4	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00026941001\|UniProtKB=A0EH26	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00024421001\|UniProtKB=A0E8S4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016072001\|UniProtKB=A0DDW4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028681001\|UniProtKB=A0BGH9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00018647001\|UniProtKB=A0DN25	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016457001\|UniProtKB=A0DF14	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00012344001\|UniProtKB=A0D1A3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00027455001\|UniProtKB=A0EII5	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_23692\|UniProtKB=B8C6I4	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_24639\|UniProtKB=B8CB97	Thalassiosira pseudonana	O