PANTHER Gene Information   
Gene Symbol(s): Eps15
Organism: Rattus norvegicus
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Gene Name: Epidermal growth factor receptor pathway substrate 15
Gene ID: 1305550
Protein ID: A0A8I5YC99
Persistent Id: PTN000131229
Alternate Ids:
ENSRNOP00000077237(Ensembl_PRO) A0A8I5YC99_RAT(UniProtKB-ID)
A0A8I5YC99(Synonym) ENSRNOT00000116078(Ensembl_TRS)
1305550(RGD) ENSRNOG00000010299(Ensembl)
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PANTHER Classification
PANTHER Family: EH DOMAIN (PTHR11216)
PANTHER Subfamily: EPIDERMAL GROWTH FACTOR RECEPTOR SUBSTRATE 15 (PTHR11216:SF54)  
PANTHER GO-slim Molecular Function: cell adhesion molecule binding
PANTHER GO-slim Biological Process: endosomal transport
endocytosis
PANTHER GO-slim Cellular Component: membrane coat
plasma membrane protein complex
clathrin-coated pit
PANTHER protein class: membrane traffic protein
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: identical protein binding, protein binding, ubiquitin binding, polyubiquitin modification-dependent protein binding, calcium ion binding
GO BP Complete: symbiont entry into host cell, regulation of protein localization, endocytosis, Golgi to endosome transport, regulation of cell population proliferation, ubiquitin-dependent endocytosis, postsynaptic neurotransmitter receptor internalization, receptor-mediated endocytosis of virus by host cell, positive regulation of receptor recycling, clathrin coat assembly, synaptic vesicle budding from presynaptic endocytic zone membrane, endosomal transport, endocytic recycling
GO CC Complete: synapse, plasma membrane, early endosome, basal plasma membrane, presynapse, postsynaptic endocytic zone, cytoplasm, clathrin-coated pit, intracellular membrane-bounded organelle, clathrin coat of coated pit, cytosol, ciliary membrane, AP-2 adaptor complex, glutamatergic synapse, clathrin-coated vesicle, aggresome, apical plasma membrane
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Cargo recognition for clathrin-mediated endocytosis, Negative regulation of MET activity, EGFR downregulation, Signaling by MET, Signaling by Receptor Tyrosine Kinases, Signal Transduction, Vesicle-mediated transport, Signaling by EGFR, Membrane Trafficking, Clathrin-mediated endocytosis

Orthologs