PANTHER Gene Information

Gene Symbol(s):

eps15

Organism:

Dictyostelium discoideum

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Gene Name:

Epidermal growth factor receptor substrate 15 homolog

Gene ID:

DDB_G0287325

Protein ID:

Q54KI4

Persistent Id:

PTN000131401

Alternate Ids:

DDB_G0287325(Ensembl)	AAFI02000100(EMBL)
XP_637239(refSeq)	EPS15_DICDI(UniProtKB-ID)
60465651(GI)	8626070(GeneID)
eps15(Symbol)	EAL63730(Ensembl_TRS)
EAL63730(Ensembl_PRO)	DDB_G0287325(dictyBase)
EAL63730(EMBL-CDS)	EPS15(Synonym)
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PANTHER Classification

PANTHER Family:	EH DOMAIN (PTHR11216)
PANTHER Subfamily:	GH06923P (PTHR11216:SF174)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	endosomal transport endocytosis
PANTHER GO-slim Cellular Component:	cytoplasm plasma membrane
PANTHER protein class:	membrane traffic protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	protein binding, calcium ion binding
GO BP Complete:	biological_process, protein transport, endosomal transport, endocytosis
GO CC Complete:	cytoplasm, clathrin coat of coated pit, AP-2 adaptor complex, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

RHOQ GTPase cycle, RHO GTPase cycle, Clathrin-mediated endocytosis, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Cell death signalling via NRAGE, NRIF and NADE, RHOG GTPase cycle, Vesicle-mediated transport, Signal Transduction, Cargo recognition for clathrin-mediated endocytosis, Death Receptor Signaling, Membrane Trafficking, RHOU GTPase cycle, Signaling by Rho GTPases, NRAGE signals death through JNK, p75 NTR receptor-mediated signalling, CDC42 GTPase cycle

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3419\|UniProtKB=P42566	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000000729.7\|UniProtKB=H2PZ06	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000006160.3\|UniProtKB=G3SBN0	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000012055.4\|UniProtKB=A0A1D5QSC4	Macaca mulatta	O
MOUSE\|MGI=MGI=104583\|UniProtKB=P42567	Mus musculus	O
RAT\|RGD=1305550\|UniProtKB=A0A8I5YC99	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000005542.6\|UniProtKB=A5D7I1	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000003872.5\|UniProtKB=A0A5G2QFX7	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000020824.4\|UniProtKB=F6WFQ1	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000027650.4\|UniProtKB=A0A5F5XD12	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845022599.1\|UniProtKB=A0A8I3PMU1	Canis lupus familiaris	O
CHICK\|Ensembl=ENSGALG00010024596.1\|UniProtKB=A0A8V0ZYI9	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000007433.4\|UniProtKB=G1KGR7	Anolis carolinensis	O
XENLA\|Gene=eps15.S\|UniProtKB=A0A8J0V6Y6	Xenopus laevis	O
XENLA\|Gene=eps15.L\|UniProtKB=A0A8J0V262	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-6070905\|UniProtKB=A0A8J0Q9H0	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000017166.2\|UniProtKB=H2MRU8	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-081104-264\|UniProtKB=F1QIJ6	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000009453.1\|UniProtKB=W5MT32	lepisosteus oculatus	O
HUMAN\|HGNC=24634\|UniProtKB=Q9UBC2	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000010644.4\|UniProtKB=H2QFP4	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000013623.3\|UniProtKB=G3RCR8	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000000994.4\|UniProtKB=A0A5F8AS86	Macaca mulatta	O
MOUSE\|MGI=MGI=104582\|UniProtKB=Q60902	Mus musculus	O
RAT\|RGD=1565708\|UniProtKB=D3ZJR1	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000009990.6\|UniProtKB=A0A3Q1MMI6	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000013857.5\|UniProtKB=A0A287B5N2	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000019452.4\|UniProtKB=A0A3Q2GSS2	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000013169.6\|UniProtKB=M3WIC2	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845030050.1\|UniProtKB=A0A8I3Q3J5	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000014917.4\|UniProtKB=F7FVU1	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000003714.4\|UniProtKB=A0A6I8N8K0	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010027936.1\|UniProtKB=A0A8V1AID8	Gallus gallus	O
XENLA\|Gene=eps15l1.S\|UniProtKB=A0A8J1LMY0	Xenopus laevis	O
XENLA\|Gene=eps15l1.L\|UniProtKB=A0A8J0UU03	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-959469\|UniProtKB=A0A6I8PPY6	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000018014.2\|UniProtKB=H2MUU0	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000002847.3\|UniProtKB=A0A3B3HT85	Oryzias latipes	O
DANRE\|Gene=eps15l1b\|UniProtKB=A0A8M9P2C3	Danio rerio	O
DANRE\|Gene=eps15l1a\|UniProtKB=A0A8M9PFY2	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000003755.1\|UniProtKB=W5M7Z5	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000009283.3\|UniProtKB=F7BA39	Ciona intestinalis	O
BRAFL\|Gene=LOC118414009\|UniProtKB=A0A9J7L012	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC583813\|UniProtKB=A0A7M7PLS9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC576532\|UniProtKB=A0A7M7PGF0	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00001224\|UniProtKB=Q9BIF4	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00025548\|UniProtKB=A8WU59	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00097714\|UniProtKB=A0A2A6BZ40	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0035060\|UniProtKB=Q9W111	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP009189\|UniProtKB=A0A1S4H0E4	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC015931\|UniProtKB=D6WTU9	Tribolium castaneum	O
HELRO\|EnsemblGenome=HelroG189047\|UniProtKB=T1FQL2	helobdella robusta	O
TRIAD\|EnsemblGenome=TriadG58856\|UniProtKB=B3S3V2	Trichoplax adhaerens	O
HUMAN\|HGNC=9963\|UniProtKB=Q8NFH8	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000021703.6\|UniProtKB=A0A2I3S580	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000016013.3\|UniProtKB=G3RIV8	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000010598.4\|UniProtKB=F7CLI2	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2663511\|UniProtKB=Q80XA6	Mus musculus	LDO
RAT\|RGD=1561642\|UniProtKB=A0A8I6AED1	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000031261.4\|UniProtKB=F1MZ73	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000012150.6\|UniProtKB=K7GP76	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000009429.4\|UniProtKB=A0A9L0RL01	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000006527.6\|UniProtKB=A0A5F5XGY0	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845030873.1\|UniProtKB=A0A8I3QZA5	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000017149.4\|UniProtKB=A0A5F8GKT0	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000003881.3\|UniProtKB=A0A6I8N8X1	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010002391.1\|UniProtKB=A0A8V0XG46	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000011590.4\|UniProtKB=G1KL98	Anolis carolinensis	LDO
XENLA\|Gene=reps2.S\|UniProtKB=A0A8J1MG29	Xenopus laevis	O
XENLA\|Gene=reps2.L\|UniProtKB=A0A1L8HG02	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-985000\|UniProtKB=F6YNR9	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000016343.2\|UniProtKB=A0A3B3IDG4	Oryzias latipes	LDO
DANRE\|Gene=reps2\|UniProtKB=A0A8M2B9B6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000007659.1\|UniProtKB=W5MLN7	lepisosteus oculatus	LDO
HUMAN\|HGNC=15578\|UniProtKB=Q96D71	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000018654.7\|UniProtKB=K7DL33	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000009083.3\|UniProtKB=G3R139	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000000224.4\|UniProtKB=A0A5K1TWN5	Macaca mulatta	O
MOUSE\|MGI=MGI=1196373\|UniProtKB=O54916	Mus musculus	O
RAT\|RGD=1307131\|UniProtKB=A0A8I6GJC5	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000012299.6\|UniProtKB=F6Q4T4	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000004146.6\|UniProtKB=F1S6Z2	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000016188.4\|UniProtKB=F6X0L0	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000014217.6\|UniProtKB=A0A337SDF1	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845021408.1\|UniProtKB=A0A8I3S2H7	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845010329.1\|UniProtKB=A0A8I3ND55	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000017316.4\|UniProtKB=F6WX13	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000020044.3\|UniProtKB=A0A6I8NGE4	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010004214.1\|UniProtKB=A0A8V0XJ00	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000004922.3\|UniProtKB=H9G9S6	Anolis carolinensis	O
XENLA\|Gene=reps1.L\|UniProtKB=A0A8J0V7T4	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-946290\|UniProtKB=Q28CL0	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000017756.2\|UniProtKB=A0A3B3I2M5	Oryzias latipes	O
DANRE\|Gene=reps1\|UniProtKB=A0A8M2B7S1	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000001188.1\|UniProtKB=W5LYZ1	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000014993.2\|UniProtKB=F6UV64	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118422571\|UniProtKB=A0A9J7LQ25	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC592824\|UniProtKB=A0A7M7PGM3	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0032341\|UniProtKB=Q8MQS4	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP008180\|UniProtKB=A0A1S4GXI5	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC005506\|UniProtKB=D6WXV2	Tribolium castaneum	LDO
EREGS\|EnsemblGenome=AGOS_AFR103W\|UniProtKB=Q754G7	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000177117\|UniProtKB=Q59SR6	Candida albicans	LDO
ENTH1\|EnsemblGenome=CL6EHI_010300\|UniProtKB=C4LYS7	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_189890\|UniProtKB=C4M720	Entamoeba histolytica	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_148600\|UniProtKB=F0ZBJ2	Dictyostelium purpureum	LDO
PLAF7\|EnsemblGenome=PF3D7_0322600\|UniProtKB=O97322	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1025000\|UniProtKB=Q8IJF4	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00026941001\|UniProtKB=A0EH26	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00024421001\|UniProtKB=A0E8S4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016072001\|UniProtKB=A0DDW4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028681001\|UniProtKB=A0BGH9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00018647001\|UniProtKB=A0DN25	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016457001\|UniProtKB=A0DF14	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00012344001\|UniProtKB=A0D1A3	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00027455001\|UniProtKB=A0EII5	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_23692\|UniProtKB=B8C6I4	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_24639\|UniProtKB=B8CB97	Thalassiosira pseudonana	LDO