PANTHER Gene Information   
Gene Symbol(s): PRKCD
Organism: Canis lupus familiaris
View Gene in Tree
Tree
Tree
Gene Name: Protein kinase C delta type
Gene ID: ENSCAFG00845028762.1
Protein ID: A0A8I3PZJ7
Persistent Id: PTN002807167
Alternate Ids:
A0A8I3PZJ7_CANLF(UniProtKB-ID) XP_005632395(refSeq)
545533147(GI) ENSCAFP00845039871(Ensembl_PRO)
A0A8I3PZJ7(Synonym) ENSCAFG00845028762(Ensembl)
ENSCAFT00845050861(Ensembl_TRS)
Show All

PANTHER Classification
PANTHER Family: SERINE/THREONINE-PROTEIN KINASE (PTHR24356)
PANTHER Subfamily: PROTEIN KINASE C DELTA TYPE (PTHR24356:SF365)  
PANTHER GO-slim Molecular Function: protein serine/threonine kinase activity
PANTHER GO-slim Biological Process: peptidyl-serine phosphorylation
intracellular signal transduction
PANTHER GO-slim Cellular Component:
PANTHER protein class: non-receptor serine/threonine protein kinase
Pathway Categories: Gonadotropin-releasing hormone receptor pathway
   PKCs
Histamine H1 receptor mediated signaling pathway
   Protein kinase C
CCKR signaling map
   PKCdelta
Apoptosis signaling pathway
   Protein kinase C
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
   Protein kinase C
Wnt signaling pathway
   Protein Kinase C
Muscarinic acetylcholine receptor 1 and 3 signaling pathway
   Protein kinase C
Oxytocin receptor mediated signaling pathway
   Protein kinase C
FGF signaling pathway
   Protein kinase C
Thyrotropin-releasing hormone receptor signaling pathway
   Protein kinase C
Angiogenesis
   Protein kinase B
Gonadotropin-releasing hormone receptor pathway
   PKCs(3)
Alpha adrenergic receptor signaling pathway
   protein kinase C
Gonadotropin-releasing hormone receptor pathway
   nPKCs
Endothelin signaling pathway
   protein kinase c
VEGF signaling pathway
   Protein kinase C
Alzheimer disease-amyloid secretase pathway
   Protein kinase C
EGF receptor signaling pathway
   PKC
B cell activation
   Protein kinase C
5HT2 type receptor mediated signaling pathway
   Protein kinase C
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: diacylglycerol-dependent, calcium-independent serine/threonine kinase activity, ATP binding, protein kinase binding, metal ion binding, insulin receptor substrate binding, enzyme activator activity, protein serine/threonine kinase activity, protein serine kinase activity
GO BP Complete: neutrophil activation, negative regulation of MAPK cascade, negative regulation of platelet aggregation, negative regulation of glial cell apoptotic process, cellular senescence, negative regulation of filopodium assembly, post-translational protein modification, cell chemotaxis, termination of signal transduction, apoptotic process, cellular response to UV, positive regulation of glucosylceramide catabolic process, cellular response to hydrogen peroxide, positive regulation of sphingomyelin catabolic process, intracellular signal transduction, cellular response to angiotensin, positive regulation of protein import into nucleus, B cell proliferation, DNA damage response, defense response to bacterium, negative regulation of insulin receptor signaling pathway, negative regulation of actin filament polymerization, immunoglobulin mediated immune response, cellular response to hydroperoxide, positive regulation of ceramide biosynthetic process, positive regulation of superoxide anion generation, positive regulation of apoptotic signaling pathway
GO CC Complete: cell-cell junction, perinuclear region of cytoplasm, cytosol, nuclear matrix, endoplasmic reticulum, plasma membrane, endolysosome
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: DAG and IP3 signaling, Regulation of mRNA stability by proteins that bind AU-rich elements, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, VEGFR2 mediated cell proliferation, Role of phospholipids in phagocytosis, G alpha (q) signalling events, Signaling by Rho GTPases, Signaling by ERBB2, Signaling by VEGF, Signaling by Receptor Tyrosine Kinases, Immune System, Neutrophil degranulation, Apoptotic cleavage of cellular proteins, Signaling by GPCR, Opioid Signalling, Interferon Signaling, Programmed Cell Death, GPCR downstream signalling, Apoptotic execution phase, HuR (ELAVL1) binds and stabilizes mRNA, Effects of PIP2 hydrolysis, CaM pathway, CLEC7A (Dectin-1) signaling, Calmodulin induced events, VEGFA-VEGFR2 Pathway, G alpha (i) signalling events, Platelet activation, signaling and aggregation, Fcgamma receptor (FCGR) dependent phagocytosis, Innate Immune System, Signal Transduction, G-protein mediated events, PLC beta mediated events, RHO GTPases Activate NADPH Oxidases, SHC1 events in ERBB2 signaling, Apoptosis, RHO GTPase Effectors, Cytokine Signaling in Immune system, Intracellular signaling by second messengers, Metabolism of RNA, Hemostasis, Ca-dependent events, Interferon gamma signaling, C-type lectin receptors (CLRs)

Orthologs