PANTHER Gene Information

Gene Symbol(s):

PRKCD

Organism:

Ornithorhynchus anatinus

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Gene Name:

protein kinase C

Gene ID:

ENSOANG00000004136.3

Protein ID:

A0A6I8NDD2

Persistent Id:

PTN001553485

Alternate Ids:

ENSOANG00000004136(Ensembl)	ENSOANP00000039077(Ensembl_PRO)
A0A6I8NDD2_ORNAN(UniProtKB-ID)	A0A6I8NDD2(Synonym)
ENSOANT00000067939(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	SERINE/THREONINE-PROTEIN KINASE (PTHR24356)
PANTHER Subfamily:	PROTEIN KINASE C DELTA TYPE (PTHR24356:SF365)
PANTHER GO-slim Molecular Function:	protein serine/threonine kinase activity
PANTHER GO-slim Biological Process:	peptidyl-serine phosphorylation intracellular signal transduction
PANTHER GO-slim Cellular Component:
PANTHER protein class:	non-receptor serine/threonine protein kinase

Pathway Categories:

Gonadotropin-releasing hormone receptor pathway

PKCs

Histamine H1 receptor mediated signaling pathway

Protein kinase C

CCKR signaling map

PKCdelta

Apoptosis signaling pathway

Protein kinase C

Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway

Protein kinase C

Wnt signaling pathway

Protein Kinase C

Muscarinic acetylcholine receptor 1 and 3 signaling pathway

Protein kinase C

Oxytocin receptor mediated signaling pathway

Protein kinase C

FGF signaling pathway

Protein kinase C

Thyrotropin-releasing hormone receptor signaling pathway

Protein kinase C

Angiogenesis

Protein kinase B

Gonadotropin-releasing hormone receptor pathway

PKCs(3)

Alpha adrenergic receptor signaling pathway

protein kinase C

Gonadotropin-releasing hormone receptor pathway

nPKCs

Endothelin signaling pathway

protein kinase c

VEGF signaling pathway

Protein kinase C

Alzheimer disease-amyloid secretase pathway

Protein kinase C

EGF receptor signaling pathway

PKC

B cell activation

Protein kinase C

5HT2 type receptor mediated signaling pathway

Protein kinase C

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity, ATP binding, protein kinase binding, metal ion binding, protein kinase activity, enzyme activator activity, protein serine/threonine kinase activity, calcium,diacylglycerol-dependent serine/threonine kinase activity, protein serine kinase activity, diacylglycerol-dependent serine/threonine kinase activity, enzyme binding
GO BP Complete:	neutrophil activation, cellular response to angiotensin, positive regulation of protein import into nucleus, negative regulation of MAPK cascade, negative regulation of glial cell apoptotic process, cellular senescence, DNA damage response, post-translational protein modification, cell chemotaxis, termination of signal transduction, regulation of actin cytoskeleton organization, apoptotic process, cellular response to UV, cellular response to hydroperoxide, positive regulation of glucosylceramide catabolic process, cellular response to hydrogen peroxide, positive regulation of sphingomyelin catabolic process, positive regulation of ceramide biosynthetic process, regulation of ceramide biosynthetic process, intracellular signal transduction, positive regulation of superoxide anion generation
GO CC Complete:	nucleus, perinuclear region of cytoplasm, cytoplasm, cytosol, endoplasmic reticulum, plasma membrane, endolysosome

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9399\|UniProtKB=Q05655	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000015023.5\|UniProtKB=K7DA70	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000003207.3\|UniProtKB=G3QL13	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000007230.4\|UniProtKB=H9EU39	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97598\|UniProtKB=P28867	Mus musculus	LDO
RAT\|RGD=67383\|UniProtKB=P09215	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000008719.6\|UniProtKB=F1MZX0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000023503.4\|UniProtKB=A0A287B8W9	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000023172.3\|UniProtKB=A0A9L0R2E0	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000003900.6\|UniProtKB=M3W161	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845028762.1\|UniProtKB=A0A8I3PZJ7	Canis lupus familiaris	LDO
CANLF\|Gene=PRKCD\|UniProtKB=Q5PU49	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000010650.4\|UniProtKB=F7D467	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010028105.1\|UniProtKB=F1P3G1	Gallus gallus	LDO
XENLA\|Gene=LOC121393421\|UniProtKB=A0A8J1KNM4	Xenopus laevis	O
XENTR\|Gene=LOC116410894\|UniProtKB=A0A8J1JKB1	Xenopus tropicalis	O
XENTR\|Gene=LOC116407930\|UniProtKB=A0A8J1IWZ7	Xenopus tropicalis	O
XENTR\|Gene=LOC100485686\|UniProtKB=A0A8J1J529	Xenopus tropicalis	O
XENLA\|Gene=LOC121402856\|UniProtKB=A0A8J1MVN2	Xenopus laevis	O
XENLA\|Gene=LOC121402976\|UniProtKB=A0A8J1MXE7	Xenopus laevis	O
XENLA\|Gene=LOC121396939\|UniProtKB=A0A8J1LGN4	Xenopus laevis	O
XENLA\|Gene=LOC108713626\|UniProtKB=A0A8J1MYU6	Xenopus laevis	O
XENLA\|Gene=LOC121393655\|UniProtKB=A0A8J1KPI4	Xenopus laevis	O
XENLA\|Gene=LOC121399692\|UniProtKB=A0A8J1M766	Xenopus laevis	O
XENLA\|Gene=LOC121396950\|UniProtKB=A0A8J1LG90	Xenopus laevis	O
XENLA\|Gene=LOC121396936\|UniProtKB=A0A8J1LHJ5	Xenopus laevis	O
XENLA\|Gene=LOC121399292\|UniProtKB=A0A8J1M1A6	Xenopus laevis	O
XENLA\|Gene=LOC121401138\|UniProtKB=A0A8J1MJ63	Xenopus laevis	O
XENTR\|Gene=LOC101735014\|UniProtKB=A0A8J1JRP3	Xenopus tropicalis	O
XENTR\|Gene=LOC116411986\|UniProtKB=A0A8J1JRR7	Xenopus tropicalis	O
XENTR\|Gene=LOC116411987\|UniProtKB=A0A8J1JRS8	Xenopus tropicalis	O
XENTR\|Gene=LOC116411985\|UniProtKB=A0A8J1JRQ6	Xenopus tropicalis	O
XENLA\|Gene=LOC108716471\|UniProtKB=A0A8J1KM08	Xenopus laevis	O
XENLA\|Gene=LOC121393577\|UniProtKB=A0A8J1KLZ1	Xenopus laevis	O
XENLA\|Gene=LOC121393579\|UniProtKB=A0A8J1KNN7	Xenopus laevis	O
XENTR\|Gene=LOC101731388\|UniProtKB=A0A8J0T4K5	Xenopus tropicalis	O
XENTR\|Gene=LOC105947923\|UniProtKB=A0A8J0T4P9	Xenopus tropicalis	O
XENLA\|Gene=LOC108718060\|UniProtKB=A0A8J0VH04	Xenopus laevis	O
XENLA\|Gene=LOC121394111\|UniProtKB=A0A8J1KTH1	Xenopus laevis	O
XENTR\|Gene=LOC101732914\|UniProtKB=A0A8J0R1B8	Xenopus tropicalis	O
XENTR\|Gene=LOC108646241\|UniProtKB=A0A8J1JAL6	Xenopus tropicalis	O
XENLA\|Gene=PKC-delta1\|UniProtKB=Q7SZH8	Xenopus laevis	O
XENLA\|Gene=prkcd.S\|UniProtKB=Q6DCJ8	Xenopus laevis	O
XENLA\|Gene=prkcd.L\|UniProtKB=A0A8J0USY1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-478663\|UniProtKB=A0A6I8SIW5	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000001443.2\|UniProtKB=A0A3B3HKM1	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-6503\|UniProtKB=Q7ZUC5	Danio rerio	LDO
DANRE\|ZFIN=ZDB-GENE-111129-1\|UniProtKB=A0A8M9QDJ7	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000014468.1\|UniProtKB=W5NB04	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118416645\|UniProtKB=A0A9J7L7P6	Branchiostoma floridae	LDO
CAEEL\|WormBase=WBGene00006599\|UniProtKB=P34722	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG01645\|UniProtKB=A8WR64	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00098542\|UniProtKB=A0A2A6BYZ3	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0287828\|UniProtKB=P83099	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP029239\|UniProtKB=A0A3F2YYX5	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC034867\|UniProtKB=A0A139WC37	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_309380\|UniProtKB=E9HCA8	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW007464\|UniProtKB=B7PUJ3	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g93932\|UniProtKB=A7RUL8	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG20496\|UniProtKB=B3RQ26	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_31267\|UniProtKB=A9USR5	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_10752\|UniProtKB=A9V750	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_21555\|UniProtKB=A9V1T6	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_34036\|UniProtKB=A9V9H6	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_39232\|UniProtKB=A9VD19	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_20766\|UniProtKB=A9UXQ2	Monosiga brevicollis	O
YEAST\|SGD=S000000201\|UniProtKB=P24583	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ACR191C\|UniProtKB=Q75BT0	Eremothecium gossypii	O
CANAL\|CGD=CAL0000201435\|UniProtKB=Q5ANK2	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_F09746g\|UniProtKB=Q6C292	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_00106\|UniProtKB=C8VQM0	Emericella nidulans	O
NEUCR\|EnsemblGenome=NCU06544\|UniProtKB=P87253	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_07073\|UniProtKB=Q0UME1	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC17G8.14c\|UniProtKB=P36582	Schizosaccharomyces pombe	O
SCHPO\|PomBase=SPBC12D12.04c\|UniProtKB=P36583	Schizosaccharomyces pombe	O
CRYNJ\|EnsemblGenome=CNE01630\|UniProtKB=Q5KH12	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNC03300\|UniProtKB=Q5KKE3	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_15023\|UniProtKB=A0A0D1DRE2	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_12641\|UniProtKB=E3KRH5	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_15370\|UniProtKB=F4NTP5	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_19449\|UniProtKB=F4P170	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_125820\|UniProtKB=C4LVW8	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_097620\|UniProtKB=C4M933	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_188930\|UniProtKB=C4M2W0	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_044470\|UniProtKB=B1N2G7	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_042150\|UniProtKB=C4M4G9	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_053040\|UniProtKB=C4M3C2	Entamoeba histolytica	O
ENTH1\|Gene_ORFName=EHI_138540\|UniProtKB=A0A8U0WPI4	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0288795\|UniProtKB=Q54IF2	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_149347\|UniProtKB=F0ZDG7	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0268620\|UniProtKB=P54644	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_152431\|UniProtKB=F0ZLC3	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_38849\|UniProtKB=F0ZVB0	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_30_0800\|UniProtKB=Q4Q7M5	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.01.2290\|UniProtKB=Q383M7	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb927.3.2690\|UniProtKB=Q582Y1	Trypanosoma brucei	O
GIAIC\|EnsemblGenome=GL50803_11364\|UniProtKB=E2RTY0	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_195270\|UniProtKB=A2FLX7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_324020\|UniProtKB=A2F4A4	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_430560\|UniProtKB=A2E382	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_316050\|UniProtKB=A2FAW3	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_447920\|UniProtKB=A2DS63	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_047250\|UniProtKB=A2FHJ2	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_267830\|UniProtKB=A2DLD2	Trichomonas vaginalis	O
SACS2\|EnsemblGenome=SSO3207\|UniProtKB=Q97U18	Sulfolobus solfataricus	O