PANTHER Gene Information

Gene Symbol(s):

ECE1

Organism:

Gallus gallus

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Gene Name:

Endothelin converting enzyme 1

Gene ID:

ENSGALG00010021126.1

Protein ID:

A0A8V0ZHS1

Persistent Id:

PTN008979484

Alternate Ids:

ENSGALP00010030350(Ensembl_PRO)	ENSGALG00010021126(Ensembl)
A0A8V0ZHS1(Synonym)	ENSGALT00010051159(Ensembl_TRS)
A0A8V0ZHS1_CHICK(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED (PTHR11733)
PANTHER Subfamily:	ENDOTHELIN-CONVERTING ENZYME 1 (PTHR11733:SF130)
PANTHER GO-slim Molecular Function:	metalloendopeptidase activity
PANTHER GO-slim Biological Process:	hormone metabolic process peptide metabolic process protein processing
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	metalloprotease

Pathway Categories:

Endothelin signaling pathway

Endothelin-coverting enzyme 1, 2, and 3

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	zinc ion binding, protein homodimerization activity, metalloendopeptidase activity
GO BP Complete:	axonogenesis involved in innervation, semaphorin-plexin signaling pathway involved in axon guidance, embryonic heart tube development, pharyngeal system development, sympathetic neuron axon guidance, embryonic digit morphogenesis, calcitonin catabolic process, endothelin maturation, positive regulation of receptor recycling, bradykinin catabolic process, ear development, substance P catabolic process, peptide hormone processing
GO CC Complete:	endosome, Weibel-Palade body, perinuclear region of cytoplasm, external side of plasma membrane, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3146\|UniProtKB=P42892	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000000298.7\|UniProtKB=K7BJM3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000012085.3\|UniProtKB=G3R8T0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000010942.4\|UniProtKB=H9FQW5	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1101357\|UniProtKB=Q4PZA2	Mus musculus	LDO
RAT\|RGD=620293\|UniProtKB=P42893	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000002977\|UniProtKB=P42891	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000003513.5\|UniProtKB=A0A5G2RMY7	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000015812.4\|UniProtKB=A0A9L0TPB8	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000014530.6\|UniProtKB=M3WKV5	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845001686.1\|UniProtKB=A0A8I3MHF9	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000016000.4\|UniProtKB=F7EYY6	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000014757.3\|UniProtKB=F7EHA3	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000005393.4\|UniProtKB=H9GA87	Anolis carolinensis	LDO
XENLA\|Gene=ece1.S\|UniProtKB=A0A8J1LAP2	Xenopus laevis	LDO
XENLA\|Gene=ece1.L\|UniProtKB=A0A8J1L456	Xenopus laevis	LDO
XENTR\|Ensembl=ENSXETG00000044790\|UniProtKB=A0A803JU36	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000017044.2\|UniProtKB=H2MRF3	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-061110-100\|UniProtKB=A0JMP1	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000003479.1\|UniProtKB=W5M719	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000007886.3\|UniProtKB=F6TGF6	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000005710.3\|UniProtKB=F6U2S1	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118405049\|UniProtKB=A0A9J7HLG4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118405047\|UniProtKB=A0A9J7HIW7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118430801\|UniProtKB=A0A9J7MAC0	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC580325\|UniProtKB=A0A7M7NXK5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC755783\|UniProtKB=A0A7M7NY20	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC578052\|UniProtKB=A0A7M7MXI0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC580975\|UniProtKB=A0A7M7SZB7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC583486\|UniProtKB=A0A7M7N0E0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC594281\|UniProtKB=A0A7M7HMZ7	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00018278\|UniProtKB=H2KZE5	Caenorhabditis elegans	O
DROME\|FlyBase=FBgn0032613\|UniProtKB=Q9VJH0	Drosophila melanogaster	O
CAEEL\|WormBase=WBGene00017393\|UniProtKB=Q09946	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG02411\|UniProtKB=A8WUD7	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00017842\|UniProtKB=A0A5S9MNU9	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00039561\|UniProtKB=A8XY73	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00279259\|UniProtKB=A0A2A6CM30	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00104229\|UniProtKB=A0A2A6CVL4	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0039277\|UniProtKB=Q9VBX6	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029586\|UniProtKB=A0A453Z012	Anopheles gambiae	O
IXOSC\|EnsemblGenome=ISCW006299\|UniProtKB=B7PM32	Ixodes scapularis	O
DROME\|FlyBase=FBgn0031678\|UniProtKB=Q9VMU6	Drosophila melanogaster	O
IXOSC\|EnsemblGenome=ISCW001618\|UniProtKB=B7P6U3	Ixodes scapularis	O
DROME\|FlyBase=FBgn0032442\|UniProtKB=Q9VK72	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0032585\|UniProtKB=Q9VJK5	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0259716\|UniProtKB=Q9VME2	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0029769\|UniProtKB=Q9W4B8	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0031808\|UniProtKB=Q9VME3	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0031081\|UniProtKB=Q9W5Y0	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP007796\|UniProtKB=A0A1S4GX10	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC015284\|UniProtKB=D2A4X8	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC015285\|UniProtKB=D2A4X7	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC015207\|UniProtKB=D2A597	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_300917\|UniProtKB=E9HFF5	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW014756\|UniProtKB=B7QM96	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG110566\|UniProtKB=T1EF32	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g229362\|UniProtKB=A7S4D9	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG37639\|UniProtKB=B3RTH7	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG63323\|UniProtKB=B3RZU7	Trichoplax adhaerens	LDO
EMENI\|EnsemblGenome=ANIA_03091\|UniProtKB=C8VIN1	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_3G12420\|UniProtKB=Q4WYB2	Neosartorya fumigata	LDO
SCLS1\|EnsemblGenome=SS1G_05697\|UniProtKB=A7EK51	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_15353\|UniProtKB=Q0TYS9	Phaeosphaeria nodorum	LDO
CRYNJ\|EnsemblGenome=CNB04230\|UniProtKB=Q5KLS5	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_02693\|UniProtKB=A0A0D1C704	Ustilago maydis	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_269863\|UniProtKB=B8LCF9	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GEF2_PHYRM\|UniProtKB=H3GEF2	Phytophthora ramorum	O
PHYRM\|Gene=H3HBZ9_PHYRM\|UniProtKB=H3HBZ9	Phytophthora ramorum	O
PHYRM\|Gene=H3H7F1_PHYRM\|UniProtKB=H3H7F1	Phytophthora ramorum	LDO
KLENI\|Gene_ORFName=KFL_000670270\|UniProtKB=A0A1Y1HUV6	Klebsormidium nitens	LDO
METAC\|EnsemblGenome=MA_2001\|UniProtKB=Q8TPB2	Methanosarcina acetivorans	LDO
MYCTU\|Gene_OrderedLocusName=Rv0198c\|UniProtKB=I6X8R2	Mycobacterium tuberculosis	LDO
STRR6\|EnsemblGenome=spr1491\|UniProtKB=Q8DNW9	Streptococcus pneumoniae	LDO
BACTN\|EnsemblGenome=BT_3811\|UniProtKB=Q8A156	Bacteroides thetaiotaomicron	LDO
SHEON\|Gene_OrderedLocusName=SO_0429\|UniProtKB=Q8EJN4	Shewanella oneidensis	LDO
SHEON\|Gene_OrderedLocusName=SO_3844\|UniProtKB=Q8EAQ3	Shewanella oneidensis	LDO
RHOBA\|EnsemblGenome=RB9029\|UniProtKB=Q7UM68	Rhodopirellula baltica	LDO
SHEON\|Gene_OrderedLocusName=SO_0491\|UniProtKB=Q8EJH4	Shewanella oneidensis	O
XANCP\|EnsemblGenome=XCC3671\|UniProtKB=Q8P4N6	Xanthomonas campestris	O
XANCP\|EnsemblGenome=XCC2710\|UniProtKB=Q8P7A3	Xanthomonas campestris	LDO
XANCP\|EnsemblGenome=XCC2035\|UniProtKB=Q8P931	Xanthomonas campestris	O
XANCP\|EnsemblGenome=XCC2575\|UniProtKB=Q8P7N6	Xanthomonas campestris	O
XANCP\|EnsemblGenome=XCC2574\|UniProtKB=Q8P7N7	Xanthomonas campestris	O