PANTHER Gene Information

Gene Symbol(s):

HAND2

Organism:

Gallus gallus

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Gene Name:

Heart- and neural crest derivatives-expressed protein 2

Gene ID:

HAND2

Protein ID:

Q90690

Persistent Id:

PTN001915635

Alternate Ids:

HAND2_CHICK(UniProtKB-ID)	1130496(GI)
AAC59733(EMBL-CDS)	U40040(EMBL)
HAND2(Synonym)	HAND2(Symbol)
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PANTHER Classification

PANTHER Family:	BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST (PTHR23349)
PANTHER Subfamily:	HEART- AND NEURAL CREST DERIVATIVES-EXPRESSED PROTEIN 2 (PTHR23349:SF41)
PANTHER GO-slim Molecular Function:	DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II transcription regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process:	heart development regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class:	basic helix-loop-helix transcription factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	RNA polymerase II transcription regulatory region sequence-specific DNA binding, protein dimerization activity, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	polarity specification of anterior/posterior axis, heart development, limb bud formation, regulation of transcription by RNA polymerase II
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=4808\|UniProtKB=P61296	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000016601.6\|UniProtKB=H2R7W4	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000006147.3\|UniProtKB=G3QTI7	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000048816.2\|UniProtKB=F7H124	Macaca mulatta	LDO
MOUSE\|MGI=MGI=103580\|UniProtKB=Q61039	Mus musculus	LDO
RAT\|RGD=621207\|UniProtKB=P61295	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000044123.3\|UniProtKB=F1MLT3	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000031537.3\|UniProtKB=A0A287BKC6	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000060197.1\|UniProtKB=A0A9L0RV01	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000043727.2\|UniProtKB=A0A337STI9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845017182.1\|UniProtKB=A0A8I3PA17	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000041860.1\|UniProtKB=A0A5F8H7L1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000043556.1\|UniProtKB=A0A6I8NJ08	Ornithorhynchus anatinus	LDO
XENLA\|Gene=hand2.S\|UniProtKB=B0BLY7	Xenopus laevis	O
XENLA\|Gene=hand2\|UniProtKB=P57101	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-481426\|UniProtKB=F7BB90	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000026925.1\|UniProtKB=A0A3B3H448	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-000511-1\|UniProtKB=P57102	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000013581.1\|UniProtKB=W5N7Z0	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006582.3\|UniProtKB=F6R0Z4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000005750.3\|UniProtKB=F6PZI7	Ciona intestinalis	O
BRAFL\|Gene=LOC118419791\|UniProtKB=H6T887	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC105438703\|UniProtKB=A0A7M7SWT8	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00001981\|UniProtKB=Q18612	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00035748\|UniProtKB=A8XM61	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00038828\|UniProtKB=A8XW38	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00031749\|UniProtKB=A8XAJ6	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00029526\|UniProtKB=A8X4N4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00203654\|UniProtKB=A0A2A6C4W9	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0032209\|UniProtKB=Q9VL05	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP004386\|UniProtKB=Q7QA78	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC004726\|UniProtKB=A0A139WNX7	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_7671\|UniProtKB=E9G5T0	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW009436\|UniProtKB=B7Q259	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG64223\|UniProtKB=T1FXR5	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG176734\|UniProtKB=T1FAU7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG136534\|UniProtKB=T1EIE4	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g199398\|UniProtKB=A7RMR1	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g106073\|UniProtKB=A7S669	Nematostella vectensis	O
CRYNJ\|EnsemblGenome=CNH00430\|UniProtKB=Q5KCB3	Cryptococcus neoformans	O