PANTHER Gene Information   
Gene Symbol(s): parp1
Organism: Danio rerio
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Gene Name: Poly [ADP-ribose] polymerase 1
Gene ID: ZDB-GENE-030131-3955
Protein ID: Q5RHR0
Persistent Id: PTN000396896
Alternate Ids:
PARP1_DANRE(UniProtKB-ID) BX470188(EMBL)
560788(GeneID) Q499A8(AltAccession)
ADP-ribosyltransferase diphtheria toxin-like 1(Synonym) ZDB-GENE-030131-3955(ZFIN)
82078243(GI) 2.4.2.30 {ECO:0000250|UniProtKB:P09874}(EC)
parp1{ECO:0000312|ZFIN:ZDB-GENE-030131-3955}(Symbol) AAI00002(EMBL-CDS)
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PANTHER Classification
PANTHER Family: DNA LIGASE (PTHR10459)
PANTHER Subfamily: POLY [ADP-RIBOSE] POLYMERASE 1 (PTHR10459:SF112)  
PANTHER GO-slim Molecular Function: catalytic activity, acting on a protein
pentosyltransferase activity
PANTHER GO-slim Biological Process: double-strand break repair
post-translational protein modification
PANTHER GO-slim Cellular Component: nucleolus
PANTHER protein class: DNA metabolism protein
Pathway Categories: FAS signaling pathway
   Poly(ADP-ribose) polymerase
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: zinc ion binding, glycosyltransferase activity, nucleotidyltransferase activity, protein homodimerization activity, nucleosome binding, NAD+-protein-glutamate ADP-ribosyltransferase activity, damaged DNA binding, NAD+-protein-tyrosine ADP-ribosyltransferase activity, NAD+-protein poly-ADP-ribosyltransferase activity, DNA binding, NAD+-protein-histidine ADP-ribosyltransferase activity, NAD+-protein-serine ADP-ribosyltransferase activity, NAD+-protein-aspartate ADP-ribosyltransferase activity, catalytic activity, metal ion binding, NAD binding, NAD+-protein ADP-ribosyltransferase activity, transferase activity, pentosyltransferase activity
GO BP Complete: negative regulation of transcription by RNA polymerase II, DNA repair, innate immune response, apoptotic process, regulation of circadian sleep/wake cycle, sleep, protein auto-ADP-ribosylation, DNA damage response, negative regulation of innate immune response, positive regulation of single strand break repair, immune system process, replication fork reversal, double-strand break repair
GO CC Complete: nucleus, site of DNA damage, cytoplasm, nuclear replication fork, cytosol, chromosome, nucleolus, chromatin
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: SUMO E3 ligases SUMOylate target proteins, Resolution of Abasic Sites (AP sites), SUMOylation of DNA damage response and repair proteins, Resolution of AP sites via the multiple-nucleotide patch replacement pathway, Nucleotide Excision Repair, Base Excision Repair, POLB-Dependent Long Patch Base Excision Repair, DNA Repair, Metabolism of proteins, Formation of Incision Complex in GG-NER, Dual Incision in GG-NER, Global Genome Nucleotide Excision Repair (GG-NER), Post-translational protein modification, DNA Damage Recognition in GG-NER, SUMOylation

Orthologs