PANTHER Gene Information   
Gene Symbol(s): PARP1
Organism: Ornithorhynchus anatinus
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Gene Name: Poly [ADP-ribose] polymerase
Gene ID: ENSOANG00000001488.3
Protein ID: F7EUJ4
Persistent Id: PTN000396893
Alternate Ids:
F7EUJ4(Synonym) ENSOANG00000001488(Ensembl)
F7EUJ4_ORNAN(UniProtKB-ID) ENSOANT00000002368(Ensembl_TRS)
ENSOANP00000002367(Ensembl_PRO)
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PANTHER Classification
PANTHER Family: DNA LIGASE (PTHR10459)
PANTHER Subfamily: POLY [ADP-RIBOSE] POLYMERASE 1 (PTHR10459:SF112)  
PANTHER GO-slim Molecular Function: catalytic activity, acting on a protein
pentosyltransferase activity
PANTHER GO-slim Biological Process: double-strand break repair
post-translational protein modification
PANTHER GO-slim Cellular Component: nucleolus
PANTHER protein class: DNA metabolism protein
Pathway Categories: FAS signaling pathway
   Poly(ADP-ribose) polymerase
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: NAD+-protein poly-ADP-ribosyltransferase activity, NAD+-protein-histidine ADP-ribosyltransferase activity, NAD+-histone H2BS6 serine ADP-ribosyltransferase activity, NAD+-histone H3S10 serine ADP-ribosyltransferase activity, NAD+-protein ADP-ribosyltransferase activity, protein kinase binding, zinc ion binding, glycosyltransferase activity, nucleotidyltransferase activity, identical protein binding, NAD DNA ADP-ribosyltransferase activity, protein homodimerization activity, nucleosome binding, chromatin binding, NAD+-protein-glutamate ADP-ribosyltransferase activity, damaged DNA binding, NAD+-protein-tyrosine ADP-ribosyltransferase activity, DNA binding, NAD+-protein-serine ADP-ribosyltransferase activity, NAD+-protein-aspartate ADP-ribosyltransferase activity, RNA polymerase II-specific DNA-binding transcription factor binding, metal ion binding, NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity, NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity, NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity, enzyme binding
GO BP Complete: DNA repair, protein modification process, mitochondrial DNA repair, negative regulation of ATP biosynthetic process, DNA ADP-ribosylation, positive regulation of double-strand break repair via homologous recombination, positive regulation of canonical NF-kappaB signal transduction, positive regulation of transcription by RNA polymerase II, negative regulation of innate immune response, double-strand break repair, negative regulation of transcription by RNA polymerase II, cellular response to insulin stimulus, negative regulation of cGAS/STING signaling pathway, apoptotic process, cellular response to UV, ATP generation from poly-ADP-D-ribose, positive regulation of DNA-templated transcription, elongation, replication fork reversal, negative regulation of transcription elongation by RNA polymerase II, regulation of protein localization, mitochondrial DNA metabolic process, DNA damage response, positive regulation of single strand break repair, mitochondrion organization, protein localization to chromatin, cellular response to oxidative stress, protein poly-ADP-ribosylation, protein auto-ADP-ribosylation, regulation of base-excision repair
GO CC Complete: site of DNA damage, nuclear body, site of double-strand break, nuclear replication fork, nucleolus, chromatin, nucleoplasm, nuclear envelope, nucleus, transcription regulator complex, mitochondrion, protein-DNA complex, cytosol, protein-containing complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: -

Orthologs