PANTHER Gene Information   
Gene Symbol(s): parp1
Organism: Xenopus tropicalis
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Gene Name: Poly [ADP-ribose] polymerase
Gene ID: XB-GENE-974935
Protein ID: A0A6I8RK86
Persistent Id: PTN008499806
Alternate Ids:
ENSXETP00000081175(Ensembl_PRO) XP_031757916(refSeq)
A0A6I8RK86(Synonym) ENSXETG00000022610(Ensembl)
A0A6I8RK86_XENTR(UniProtKB-ID) ENSXETT00000082643(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: DNA LIGASE (PTHR10459)
PANTHER Subfamily: POLY [ADP-RIBOSE] POLYMERASE 1 (PTHR10459:SF112)  
PANTHER GO-slim Molecular Function: catalytic activity, acting on a protein
pentosyltransferase activity
PANTHER GO-slim Biological Process: double-strand break repair
post-translational protein modification
PANTHER GO-slim Cellular Component: nucleolus
PANTHER protein class: DNA metabolism protein
Pathway Categories: FAS signaling pathway
   Poly(ADP-ribose) polymerase

GO MF Complete: DNA binding, zinc ion binding, glycosyltransferase activity, nucleotidyltransferase activity, metal ion binding, NAD binding, NAD+-protein ADP-ribosyltransferase activity, NAD+-protein poly-ADP-ribosyltransferase activity
GO BP Complete: DNA repair, regulation of circadian sleep/wake cycle, sleep, positive regulation of single strand break repair, double-strand break repair
GO CC Complete: nucleus, chromosome, nucleolus
Reactome Pathways: Formation of Incision Complex in GG-NER, DNA Damage Recognition in GG-NER, Resolution of Abasic Sites (AP sites), Dual Incision in GG-NER, Metabolism of proteins, SUMOylation, Global Genome Nucleotide Excision Repair (GG-NER), Nucleotide Excision Repair, Post-translational protein modification, SUMO E3 ligases SUMOylate target proteins, Resolution of AP sites via the multiple-nucleotide patch replacement pathway, POLB-Dependent Long Patch Base Excision Repair, Base Excision Repair, SUMOylation of DNA damage response and repair proteins, DNA Repair