PANTHER Gene Information

Gene Symbol(s):

arpc1a

Organism:

Danio rerio

View Gene in Tree


Tree	Reduced Tree

Gene Name:

Actin-related protein 2_3 complex subunit

Gene ID:

ZDB-GENE-030131-7414

Protein ID:

Q7T372

Persistent Id:

PTN000076244

Alternate Ids:

ZDB-GENE-030131-7414(ZFIN)	335474(GeneID)
BC164463(EMBL)	ENSDARP00000038520(Ensembl_PRO)
ENSDART00000033713(Ensembl_TRS)	Q7T372(Synonym)
AAH53229(EMBL-CDS)	ENSDARG00000027063(Ensembl)
NP_998321(refSeq)	31419515(GI)
Q7T372_DANRE(UniProtKB-ID)
Show All

PANTHER Classification

PANTHER Family:	ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 (PTHR10709)
PANTHER Subfamily:	ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 1B (PTHR10709:SF10)
PANTHER GO-slim Molecular Function:	actin filament binding
PANTHER GO-slim Biological Process:	Arp2/3 complex-mediated actin nucleation
PANTHER GO-slim Cellular Component:	Arp2/3 protein complex
PANTHER protein class:	actin or actin-binding cytoskeletal protein

Pathway Categories:

Inflammation mediated by chemokine and cytokine signaling pathway

Actin related protein 2/3 complex

Integrin signalling pathway

Actin related protein 2/3 complex

Cytoskeletal regulation by Rho GTPase

Actin related protein 2/3 complex

Huntington disease

Actin related protein 2/3 complex

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	actin filament binding, actin binding
GO BP Complete:	T cell differentiation, Arp2/3 complex-mediated actin nucleation, thrombocyte differentiation
GO CC Complete:	nucleus, cytoskeleton, cytoplasm, actin cytoskeleton, Arp2/3 protein complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Regulation of actin dynamics for phagocytic cup formation, Axon guidance, Nervous system development, Signal Transduction, Fcgamma receptor (FCGR) dependent phagocytosis, EPH-Ephrin signaling, EPHB-mediated forward signaling, RHO GTPase Effectors, Immune System, Signaling by Rho GTPases, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Innate Immune System, RHO GTPases Activate WASPs and WAVEs, Developmental Biology

Orthologs

ID	Organism	Type
HUMAN\|HGNC=704\|UniProtKB=O15143	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000019449.5\|UniProtKB=H2QV01	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000013186.3\|UniProtKB=G3RBK8	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=1343142\|UniProtKB=Q9WV32	Mus musculus	LDO
RAT\|RGD=2155\|UniProtKB=O88656	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000020684.4\|UniProtKB=A0A3Q1LGG1	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000046248\|UniProtKB=Q58CQ2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000007625.5\|UniProtKB=B5APU6	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000024991.4\|UniProtKB=A0A3Q2HCF8	Equus caballus	LDO
CANLF\|Ensembl=ENSCAFG00845003541.1\|UniProtKB=A0A8I3MVD4	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000001316.4\|UniProtKB=F7BE06	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000007725.4\|UniProtKB=F6QT91	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010021362.1\|UniProtKB=A0A8V0ZJA4	Gallus gallus	LDO
XENLA\|Gene=arpc1b.L\|UniProtKB=A0A8J1LQP8	Xenopus laevis	O
XENLA\|Gene_ORFName=XELAEV_18045069mg\|UniProtKB=Q7ZXD5	Xenopus laevis	O
XENLA\|Gene_ORFName=XELAEV_18047442mg\|UniProtKB=Q6GNU1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-490410\|UniProtKB=Q6DF56	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000009068.2\|UniProtKB=A0A3B3H8R8	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000004536.1\|UniProtKB=W5MAL4	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004481.3\|UniProtKB=F6TEZ1	Ciona intestinalis	O
BRAFL\|Gene=LOC118429270\|UniProtKB=A0A9J7M8V7	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC581455\|UniProtKB=A0A7M7HPN8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC585909\|UniProtKB=A0A7M7NSH7	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00000201\|UniProtKB=A0A3P6PCS5	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG18174\|UniProtKB=A8XT67	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00274703\|UniProtKB=A0A2A6CY92	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00274999\|UniProtKB=A0A2A6BP68	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0001961\|UniProtKB=O97182	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP008908\|UniProtKB=Q7PWN2	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC000050\|UniProtKB=D6WDC6	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_300535\|UniProtKB=E9HDB8	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW011129\|UniProtKB=B7Q740	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG185993\|UniProtKB=T1FNJ1	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g236117\|UniProtKB=A7SZA7	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG60814\|UniProtKB=B3S988	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_35994\|UniProtKB=A9UR80	Monosiga brevicollis	O
YEAST\|SGD=S000000438\|UniProtKB=P38328	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AFL022W\|UniProtKB=Q754U3	Eremothecium gossypii	O
CANAL\|CGD=CAL0000175984\|UniProtKB=A0A1D8PT60	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_B17380g\|UniProtKB=Q6CE98	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_05778\|UniProtKB=Q5B102	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_6G06500\|UniProtKB=Q4WNG0	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU02781\|UniProtKB=Q7SE13	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_04510\|UniProtKB=A7EGR8	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_03354\|UniProtKB=Q0UY10	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC14C8.06\|UniProtKB=P78774	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_02075\|UniProtKB=B6JZN3	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNF00940\|UniProtKB=Q5KFQ5	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_05906\|UniProtKB=A0A0D1DQB3	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_02224\|UniProtKB=E3JXI8	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_18271\|UniProtKB=F4NT44	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_045000\|UniProtKB=C4LTB5	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_094120\|UniProtKB=C4LYJ9	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0277825\|UniProtKB=O96622	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_95056\|UniProtKB=F0ZRS0	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_18_0920\|UniProtKB=Q4QDV0	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.389.0270\|UniProtKB=Q388S8	Trypanosoma brucei	O
TRIV3\|Gene_ORFName=TVAG_035180\|UniProtKB=A2DAJ2	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_1118800\|UniProtKB=Q8IIH9	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00010112001\|UniProtKB=A0CSS3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00006678001\|UniProtKB=A0C9A5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00002218001\|UniProtKB=A0DGC2	Paramecium tetraurelia	O
PHYRM\|Gene=H3GNT1_PHYRM\|UniProtKB=H3GNT1	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_16g648100v5\|UniProtKB=A0A2K3CSQ7	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00039p00197260\|UniProtKB=U5CRM6	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_15G01330\|UniProtKB=A0A0K9PV25	Zostera marina	O
MUSAM\|EnsemblGenome=Ma11_g07370\|UniProtKB=A0A804L5A3	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_017523mg\|UniProtKB=K3YTC8	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3004G345400\|UniProtKB=A0A194YU89	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb258930\|UniProtKB=C4IZE9	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb191400\|UniProtKB=B6TA39	Zea mays	O
ORYSJ\|EnsemblGenome=Os02g0817200\|UniProtKB=Q6K699	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g55390v3\|UniProtKB=I1IDX5	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0629710\|UniProtKB=A0A8I6YX20	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS6B02G432000\|UniProtKB=A0A3B6PTP7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCSU02G081300\|UniProtKB=A0A341ZB41	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G377800\|UniProtKB=A0A3B6QKZ3	Triticum aestivum	O
NELNU\|Gene=LOC104608427\|UniProtKB=A0A1U8QAN3	Nelumbo nucifera	O
NELNU\|Gene=LOC104609009\|UniProtKB=A0A1U8AYS2	Nelumbo nucifera	O
SPIOL\|Gene=LOC110783720\|UniProtKB=A0A9R0I6W9	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr16g0756401\|UniProtKB=A0A251S1U5	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C400178040\|UniProtKB=A0A9R1VSC6	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a008285mg\|UniProtKB=A0A022S272	Erythranthe guttata	O
SOLLC\|EnsemblGenome=Solyc05g006470.3\|UniProtKB=A0A3Q7GDR2	Solanum lycopersicum	O
TOBAC\|Gene=LOC107784652\|UniProtKB=A0A1S3ZA87	Nicotiana tabacum	O
TOBAC\|Gene=LOC107832594\|UniProtKB=A0A1S4DR85	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi12g02215\|UniProtKB=E0CTY0	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_K01189\|UniProtKB=A0A058ZZP8	Eucalyptus grandis	O
BRANA\|Gene_ORFName=DARMORV10_A05P14760.1\|UniProtKB=A0A078FF85	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C03P20380.1\|UniProtKB=A0A078GBX8	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00043385001\|UniProtKB=A0A078GYH3	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C04P19760.1\|UniProtKB=A0A078ICQ8	Brassica napus	O
BRACM\|EnsemblGenome=Bra021676\|UniProtKB=M4DYT0	Brassica campestris	O
BRACM\|EnsemblGenome=Bra022818\|UniProtKB=M4E218	Brassica campestris	O
ARATH\|TAIR=locus=2042491\|UniProtKB=Q9SJW6	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2052871\|UniProtKB=O80856	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107896882\|UniProtKB=A0A1U8IMN2	Gossypium hirsutum	O
GOSHI\|Gene=LOC107914491\|UniProtKB=A0A1U8K8T5	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_001800\|UniProtKB=A0A061DJX7	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g016982mg\|UniProtKB=A0A067EU28	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_014G141700v3\|UniProtKB=B9IA44	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_02G087100\|UniProtKB=A0A2C9WC45	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_01G129200\|UniProtKB=A0A251LR00	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0540370\|UniProtKB=B9SIS1	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_10G216300\|UniProtKB=I1LD74	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_18G103800\|UniProtKB=I1N0U4	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_08G311700\|UniProtKB=K7LA18	Glycine max	O
MEDTR\|EnsemblGenome=MTR_3g049070\|UniProtKB=G7IZZ4	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr10_16440\|UniProtKB=A0A2I4F971	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_6G422800\|UniProtKB=A0A0A0KHX9	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_3G170000\|UniProtKB=M5X5D3	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_140479\|UniProtKB=D8QRC4	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_171977\|UniProtKB=D8RJH8	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c18_4810\|UniProtKB=A0A2K1IZY5	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c19_12930\|UniProtKB=A0A2K1IY81	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0116s0052\|UniProtKB=A0A2R6WB43	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0090s0056\|UniProtKB=A0A2R6WHJ8	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_000020310\|UniProtKB=A0A1Y1HKK6	Klebsormidium nitens	O