PANTHER Gene Information

Gene Symbol(s):

arcA

Organism:

Dictyostelium discoideum

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Gene Name:

Actin-related protein 2_3 complex subunit 1

Gene ID:

DDB_G0277825

Protein ID:

O96622

Persistent Id:

PTN000076303

Alternate Ids:

DDB_G0277825(dictyBase)	60470105(GI)
EAL68085(Ensembl_PRO)	arpD(Synonym)
XP_642137(refSeq)	8621345(GeneID)
EAL68085(Ensembl_TRS)	arcA(Symbol)
AAC99777(EMBL-CDS)	AAFI02000023(EMBL)
Q54YR5(AltAccession)	DDB_G0277825(Ensembl)
ARPC1_DICDI(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 (PTHR10709)
PANTHER Subfamily:	ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT (PTHR10709:SF2)
PANTHER GO-slim Molecular Function:	actin filament binding
PANTHER GO-slim Biological Process:	Arp2/3 complex-mediated actin nucleation
PANTHER GO-slim Cellular Component:	Arp2/3 protein complex
PANTHER protein class:	actin or actin-binding cytoskeletal protein

Pathway Categories:

Inflammation mediated by chemokine and cytokine signaling pathway

Actin related protein 2/3 complex

Integrin signalling pathway

Actin related protein 2/3 complex

Huntington disease

Actin related protein 2/3 complex

Cytoskeletal regulation by Rho GTPase

Actin related protein 2/3 complex

GENE ONTOLOGY DATABASE ANNOTATIONS

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REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Signaling by Rho GTPases, Miro GTPases and RHOBTB3, RHO GTPase Effectors, Signal Transduction, Immune System, RHO GTPases Activate WASPs and WAVEs, Signaling by Rho GTPases, Innate Immune System, Regulation of actin dynamics for phagocytic cup formation, Fcgamma receptor (FCGR) dependent phagocytosis

Orthologs

ID	Organism	Type
HUMAN\|HGNC=704\|UniProtKB=O15143	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000019449.5\|UniProtKB=H2QV01	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000013186.3\|UniProtKB=G3RBK8	Gorilla gorilla gorilla	O
MOUSE\|MGI=MGI=1343142\|UniProtKB=Q9WV32	Mus musculus	O
RAT\|RGD=2155\|UniProtKB=O88656	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000020684.4\|UniProtKB=A0A3Q1LGG1	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000046248\|UniProtKB=Q58CQ2	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000007625.5\|UniProtKB=B5APU6	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000024991.4\|UniProtKB=A0A3Q2HCF8	Equus caballus	O
CANLF\|Ensembl=ENSCAFG00845003541.1\|UniProtKB=A0A8I3MVD4	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000001316.4\|UniProtKB=F7BE06	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000007725.4\|UniProtKB=F6QT91	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010021362.1\|UniProtKB=A0A8V0ZJA4	Gallus gallus	O
XENLA\|Gene=arpc1b.L\|UniProtKB=A0A8J1LQP8	Xenopus laevis	O
XENLA\|Gene_ORFName=XELAEV_18045069mg\|UniProtKB=Q7ZXD5	Xenopus laevis	O
XENLA\|Gene_ORFName=XELAEV_18047442mg\|UniProtKB=Q6GNU1	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-490410\|UniProtKB=Q6DF56	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000009068.2\|UniProtKB=A0A3B3H8R8	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030131-7414\|UniProtKB=Q7T372	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000004536.1\|UniProtKB=W5MAL4	lepisosteus oculatus	O
XENLA\|Gene=LOC108701201\|UniProtKB=A0A1L8EUX9	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000017356.2\|UniProtKB=H2MSH0	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040625-80\|UniProtKB=A9JRP8	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000012417.1\|UniProtKB=W5N3T2	lepisosteus oculatus	LDO
PANTR\|Ensembl=ENSPTRG00000051667.1\|UniProtKB=A0A2I3TQ84	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000039925.1\|UniProtKB=A0A2I2YC68	Gorilla gorilla gorilla	O
PANTR\|Ensembl=ENSPTRG00000050251.1\|UniProtKB=A0A2I3T7D9	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000037353.1\|UniProtKB=A0A2I2YDG6	Gorilla gorilla gorilla	O
HUMAN\|HGNC=703\|UniProtKB=Q92747	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000033819.3\|UniProtKB=H2QV00	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000039217.1\|UniProtKB=G3R1E2	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000001458.4\|UniProtKB=H9FNS7	Macaca mulatta	O
MOUSE\|MGI=MGI=1928896\|UniProtKB=Q9R0Q6	Mus musculus	O
RAT\|RGD=620834\|UniProtKB=Q99PD4	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000049440.1\|UniProtKB=A0A3Q1NMB5	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000004242\|UniProtKB=Q1JP79	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000007609.5\|UniProtKB=F1REX9	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000050899.1\|UniProtKB=A0A9L0S565	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000015065.6\|UniProtKB=M3WLV8	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845003616.1\|UniProtKB=A0A8I3MPK0	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000048722.1\|UniProtKB=A0A5F8G810	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000016729.3\|UniProtKB=A0A5F8HHQ2	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000001303.4\|UniProtKB=F7BZM9	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000007724.4\|UniProtKB=F6QTB5	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010021325.1\|UniProtKB=A0A8V0ZJ54	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000012777.4\|UniProtKB=H9GJ97	Anolis carolinensis	O
XENLA\|Gene_ORFName=XELAEV_18047443mg\|UniProtKB=Q8AVT9	Xenopus laevis	O
XENLA\|Gene_ORFName=XELAEV_18045070mg\|UniProtKB=A0A1L8EXB5	Xenopus laevis	O
XENLA\|Gene=arpc1a.S\|UniProtKB=A0A8J0U071	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-6034682\|UniProtKB=Q28I17	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000009096.2\|UniProtKB=H2LZ39	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040116-1\|UniProtKB=Q7ZUQ0	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000004549.1\|UniProtKB=W5MAM8	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000004481.3\|UniProtKB=F6TEZ1	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118429270\|UniProtKB=A0A9J7M8V7	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC581455\|UniProtKB=A0A7M7HPN8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC585909\|UniProtKB=A0A7M7NSH7	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00000201\|UniProtKB=A0A3P6PCS5	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG18174\|UniProtKB=A8XT67	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00274703\|UniProtKB=A0A2A6CY92	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00274999\|UniProtKB=A0A2A6BP68	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0001961\|UniProtKB=O97182	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP008908\|UniProtKB=Q7PWN2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC000050\|UniProtKB=D6WDC6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_300535\|UniProtKB=E9HDB8	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW011129\|UniProtKB=B7Q740	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG185993\|UniProtKB=T1FNJ1	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g236117\|UniProtKB=A7SZA7	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG60814\|UniProtKB=B3S988	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_35994\|UniProtKB=A9UR80	Monosiga brevicollis	LDO
YEAST\|SGD=S000000438\|UniProtKB=P38328	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFL022W\|UniProtKB=Q754U3	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000175984\|UniProtKB=A0A1D8PT60	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_B17380g\|UniProtKB=Q6CE98	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_05778\|UniProtKB=Q5B102	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_6G06500\|UniProtKB=Q4WNG0	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU02781\|UniProtKB=Q7SE13	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_04510\|UniProtKB=A7EGR8	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_03354\|UniProtKB=Q0UY10	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC14C8.06\|UniProtKB=P78774	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02075\|UniProtKB=B6JZN3	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNF00940\|UniProtKB=Q5KFQ5	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_05906\|UniProtKB=A0A0D1DQB3	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_02224\|UniProtKB=E3JXI8	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_18271\|UniProtKB=F4NT44	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_045000\|UniProtKB=C4LTB5	Entamoeba histolytica	LDO
ENTH1\|EnsemblGenome=CL6EHI_094120\|UniProtKB=C4LYJ9	Entamoeba histolytica	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_95056\|UniProtKB=F0ZRS0	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_18_0920\|UniProtKB=Q4QDV0	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb10.389.0270\|UniProtKB=Q388S8	Trypanosoma brucei	LDO
TRIV3\|Gene_ORFName=TVAG_035180\|UniProtKB=A2DAJ2	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_1118800\|UniProtKB=Q8IIH9	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00010112001\|UniProtKB=A0CSS3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00006678001\|UniProtKB=A0C9A5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00002218001\|UniProtKB=A0DGC2	Paramecium tetraurelia	LDO
PHYRM\|Gene=H3GNT1_PHYRM\|UniProtKB=H3GNT1	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_16g648100v5\|UniProtKB=A0A2K3CSQ7	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00039p00197260\|UniProtKB=U5CRM6	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_15G01330\|UniProtKB=A0A0K9PV25	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma11_g07370\|UniProtKB=A0A804L5A3	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_017523mg\|UniProtKB=K3YTC8	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G345400\|UniProtKB=A0A194YU89	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb258930\|UniProtKB=C4IZE9	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb191400\|UniProtKB=B6TA39	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os02g0817200\|UniProtKB=Q6K699	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g55390v3\|UniProtKB=I1IDX5	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0629710\|UniProtKB=A0A8I6YX20	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6B02G432000\|UniProtKB=A0A3B6PTP7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCSU02G081300\|UniProtKB=A0A341ZB41	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G377800\|UniProtKB=A0A3B6QKZ3	Triticum aestivum	LDO
NELNU\|Gene=LOC104608427\|UniProtKB=A0A1U8QAN3	Nelumbo nucifera	O
NELNU\|Gene=LOC104609009\|UniProtKB=A0A1U8AYS2	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110783720\|UniProtKB=A0A9R0I6W9	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr16g0756401\|UniProtKB=A0A251S1U5	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C400178040\|UniProtKB=A0A9R1VSC6	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a008285mg\|UniProtKB=A0A022S272	Erythranthe guttata	LDO
SOLLC\|EnsemblGenome=Solyc05g006470.3\|UniProtKB=A0A3Q7GDR2	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107784652\|UniProtKB=A0A1S3ZA87	Nicotiana tabacum	O
TOBAC\|Gene=LOC107832594\|UniProtKB=A0A1S4DR85	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi12g02215\|UniProtKB=E0CTY0	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_K01189\|UniProtKB=A0A058ZZP8	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_A05P14760.1\|UniProtKB=A0A078FF85	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C03P20380.1\|UniProtKB=A0A078GBX8	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00043385001\|UniProtKB=A0A078GYH3	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C04P19760.1\|UniProtKB=A0A078ICQ8	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra021676\|UniProtKB=M4DYT0	Brassica campestris	O
BRACM\|EnsemblGenome=Bra022818\|UniProtKB=M4E218	Brassica campestris	LDO
ARATH\|TAIR=locus=2042491\|UniProtKB=Q9SJW6	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2052871\|UniProtKB=O80856	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107896882\|UniProtKB=A0A1U8IMN2	Gossypium hirsutum	O
GOSHI\|Gene=LOC107914491\|UniProtKB=A0A1U8K8T5	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_001800\|UniProtKB=A0A061DJX7	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g016982mg\|UniProtKB=A0A067EU28	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_014G141700v3\|UniProtKB=B9IA44	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_02G087100\|UniProtKB=A0A2C9WC45	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_01G129200\|UniProtKB=A0A251LR00	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0540370\|UniProtKB=B9SIS1	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_10G216300\|UniProtKB=I1LD74	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_18G103800\|UniProtKB=I1N0U4	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_08G311700\|UniProtKB=K7LA18	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_3g049070\|UniProtKB=G7IZZ4	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr10_16440\|UniProtKB=A0A2I4F971	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_6G422800\|UniProtKB=A0A0A0KHX9	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_3G170000\|UniProtKB=M5X5D3	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_140479\|UniProtKB=D8QRC4	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_171977\|UniProtKB=D8RJH8	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c18_4810\|UniProtKB=A0A2K1IZY5	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c19_12930\|UniProtKB=A0A2K1IY81	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0116s0052\|UniProtKB=A0A2R6WB43	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0090s0056\|UniProtKB=A0A2R6WHJ8	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000020310\|UniProtKB=A0A1Y1HKK6	Klebsormidium nitens	LDO