PANTHER Gene Information

Gene Symbol(s):

ARPC1A

Organism:

Bos taurus

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Gene Name:

Actin-related protein 2_3 complex subunit 1A

Gene ID:

ENSBTAG00000004242

Protein ID:

Q1JP79

Persistent Id:

PTN007456776

Alternate Ids:

BT025475(EMBL)	ARC1A_BOVIN(UniProtKB-ID)
XP_005225118(refSeq)	ARC1A(Synonym)
508402(GeneID)	A6QLF5(AltAccession)
ABF57431(EMBL-CDS)	ENSBTAG00000004242(Ensembl)
ENSBTAT00000005555(Ensembl_TRS)	151554825(GI)
ENSBTAP00000005555(Ensembl_PRO)	ARPC1A(Symbol)
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PANTHER Classification

PANTHER Family:	ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 (PTHR10709)
PANTHER Subfamily:	ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 1A (PTHR10709:SF11)
PANTHER GO-slim Molecular Function:	actin filament binding
PANTHER GO-slim Biological Process:	Arp2/3 complex-mediated actin nucleation
PANTHER GO-slim Cellular Component:	Arp2/3 protein complex
PANTHER protein class:	actin or actin-binding cytoskeletal protein

Pathway Categories:

Inflammation mediated by chemokine and cytokine signaling pathway

Actin related protein 2/3 complex

Integrin signalling pathway

Actin related protein 2/3 complex

Cytoskeletal regulation by Rho GTPase

Actin related protein 2/3 complex

Huntington disease

Actin related protein 2/3 complex

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	actin filament binding
GO BP Complete:	Arp2/3 complex-mediated actin nucleation
GO CC Complete:	nucleus, site of double-strand break, muscle cell projection membrane, cytoplasm, glutamatergic synapse, Arp2/3 protein complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Regulation of actin dynamics for phagocytic cup formation, Axon guidance, Clathrin-mediated endocytosis, Membrane Trafficking, Immune System, RHO GTPases Activate WASPs and WAVEs, Signal Transduction, Innate Immune System, Developmental Biology, Vesicle-mediated transport, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Nervous system development, EPH-Ephrin signaling, RHO GTPase Effectors, EPHB-mediated forward signaling, Signaling by Rho GTPases, Fcgamma receptor (FCGR) dependent phagocytosis

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000051667.1\|UniProtKB=A0A2I3TQ84	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000039925.1\|UniProtKB=A0A2I2YC68	Gorilla gorilla gorilla	O
PANTR\|Ensembl=ENSPTRG00000050251.1\|UniProtKB=A0A2I3T7D9	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000037353.1\|UniProtKB=A0A2I2YDG6	Gorilla gorilla gorilla	O
HUMAN\|HGNC=703\|UniProtKB=Q92747	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000033819.3\|UniProtKB=H2QV00	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000039217.1\|UniProtKB=G3R1E2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000001458.4\|UniProtKB=H9FNS7	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1928896\|UniProtKB=Q9R0Q6	Mus musculus	LDO
RAT\|RGD=620834\|UniProtKB=Q99PD4	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000007609.5\|UniProtKB=F1REX9	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000050899.1\|UniProtKB=A0A9L0S565	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000015065.6\|UniProtKB=M3WLV8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845003616.1\|UniProtKB=A0A8I3MPK0	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000048722.1\|UniProtKB=A0A5F8G810	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000016729.3\|UniProtKB=A0A5F8HHQ2	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000001303.4\|UniProtKB=F7BZM9	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000007724.4\|UniProtKB=F6QTB5	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010021325.1\|UniProtKB=A0A8V0ZJ54	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000012777.4\|UniProtKB=H9GJ97	Anolis carolinensis	LDO
XENLA\|Gene_ORFName=XELAEV_18047443mg\|UniProtKB=Q8AVT9	Xenopus laevis	LDO
XENLA\|Gene_ORFName=XELAEV_18045070mg\|UniProtKB=A0A1L8EXB5	Xenopus laevis	O
XENLA\|Gene=arpc1a.S\|UniProtKB=A0A8J0U071	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-6034682\|UniProtKB=Q28I17	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000009096.2\|UniProtKB=H2LZ39	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040116-1\|UniProtKB=Q7ZUQ0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000004549.1\|UniProtKB=W5MAM8	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004481.3\|UniProtKB=F6TEZ1	Ciona intestinalis	O
BRAFL\|Gene=LOC118429270\|UniProtKB=A0A9J7M8V7	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC581455\|UniProtKB=A0A7M7HPN8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC585909\|UniProtKB=A0A7M7NSH7	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00000201\|UniProtKB=A0A3P6PCS5	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG18174\|UniProtKB=A8XT67	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00274703\|UniProtKB=A0A2A6CY92	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00274999\|UniProtKB=A0A2A6BP68	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0001961\|UniProtKB=O97182	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP008908\|UniProtKB=Q7PWN2	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC000050\|UniProtKB=D6WDC6	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_300535\|UniProtKB=E9HDB8	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW011129\|UniProtKB=B7Q740	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG185993\|UniProtKB=T1FNJ1	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g236117\|UniProtKB=A7SZA7	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG60814\|UniProtKB=B3S988	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_35994\|UniProtKB=A9UR80	Monosiga brevicollis	O
YEAST\|SGD=S000000438\|UniProtKB=P38328	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AFL022W\|UniProtKB=Q754U3	Eremothecium gossypii	O
CANAL\|CGD=CAL0000175984\|UniProtKB=A0A1D8PT60	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_B17380g\|UniProtKB=Q6CE98	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_05778\|UniProtKB=Q5B102	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_6G06500\|UniProtKB=Q4WNG0	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU02781\|UniProtKB=Q7SE13	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_04510\|UniProtKB=A7EGR8	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_03354\|UniProtKB=Q0UY10	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC14C8.06\|UniProtKB=P78774	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_02075\|UniProtKB=B6JZN3	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNF00940\|UniProtKB=Q5KFQ5	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_05906\|UniProtKB=A0A0D1DQB3	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_02224\|UniProtKB=E3JXI8	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_18271\|UniProtKB=F4NT44	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_045000\|UniProtKB=C4LTB5	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_094120\|UniProtKB=C4LYJ9	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0277825\|UniProtKB=O96622	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_95056\|UniProtKB=F0ZRS0	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_18_0920\|UniProtKB=Q4QDV0	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.389.0270\|UniProtKB=Q388S8	Trypanosoma brucei	O
TRIV3\|Gene_ORFName=TVAG_035180\|UniProtKB=A2DAJ2	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_1118800\|UniProtKB=Q8IIH9	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00010112001\|UniProtKB=A0CSS3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00006678001\|UniProtKB=A0C9A5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00002218001\|UniProtKB=A0DGC2	Paramecium tetraurelia	O
PHYRM\|Gene=H3GNT1_PHYRM\|UniProtKB=H3GNT1	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_16g648100v5\|UniProtKB=A0A2K3CSQ7	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00039p00197260\|UniProtKB=U5CRM6	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_15G01330\|UniProtKB=A0A0K9PV25	Zostera marina	O
MUSAM\|EnsemblGenome=Ma11_g07370\|UniProtKB=A0A804L5A3	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_017523mg\|UniProtKB=K3YTC8	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3004G345400\|UniProtKB=A0A194YU89	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb258930\|UniProtKB=C4IZE9	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb191400\|UniProtKB=B6TA39	Zea mays	O
ORYSJ\|EnsemblGenome=Os02g0817200\|UniProtKB=Q6K699	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g55390v3\|UniProtKB=I1IDX5	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0629710\|UniProtKB=A0A8I6YX20	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS6B02G432000\|UniProtKB=A0A3B6PTP7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCSU02G081300\|UniProtKB=A0A341ZB41	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G377800\|UniProtKB=A0A3B6QKZ3	Triticum aestivum	O
NELNU\|Gene=LOC104608427\|UniProtKB=A0A1U8QAN3	Nelumbo nucifera	O
NELNU\|Gene=LOC104609009\|UniProtKB=A0A1U8AYS2	Nelumbo nucifera	O
SPIOL\|Gene=LOC110783720\|UniProtKB=A0A9R0I6W9	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr16g0756401\|UniProtKB=A0A251S1U5	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C400178040\|UniProtKB=A0A9R1VSC6	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a008285mg\|UniProtKB=A0A022S272	Erythranthe guttata	O
SOLLC\|EnsemblGenome=Solyc05g006470.3\|UniProtKB=A0A3Q7GDR2	Solanum lycopersicum	O
TOBAC\|Gene=LOC107784652\|UniProtKB=A0A1S3ZA87	Nicotiana tabacum	O
TOBAC\|Gene=LOC107832594\|UniProtKB=A0A1S4DR85	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi12g02215\|UniProtKB=E0CTY0	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_K01189\|UniProtKB=A0A058ZZP8	Eucalyptus grandis	O
BRANA\|Gene_ORFName=DARMORV10_A05P14760.1\|UniProtKB=A0A078FF85	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C03P20380.1\|UniProtKB=A0A078GBX8	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00043385001\|UniProtKB=A0A078GYH3	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C04P19760.1\|UniProtKB=A0A078ICQ8	Brassica napus	O
BRACM\|EnsemblGenome=Bra021676\|UniProtKB=M4DYT0	Brassica campestris	O
BRACM\|EnsemblGenome=Bra022818\|UniProtKB=M4E218	Brassica campestris	O
ARATH\|TAIR=locus=2042491\|UniProtKB=Q9SJW6	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2052871\|UniProtKB=O80856	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107896882\|UniProtKB=A0A1U8IMN2	Gossypium hirsutum	O
GOSHI\|Gene=LOC107914491\|UniProtKB=A0A1U8K8T5	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_001800\|UniProtKB=A0A061DJX7	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g016982mg\|UniProtKB=A0A067EU28	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_014G141700v3\|UniProtKB=B9IA44	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_02G087100\|UniProtKB=A0A2C9WC45	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_01G129200\|UniProtKB=A0A251LR00	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0540370\|UniProtKB=B9SIS1	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_10G216300\|UniProtKB=I1LD74	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_18G103800\|UniProtKB=I1N0U4	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_08G311700\|UniProtKB=K7LA18	Glycine max	O
MEDTR\|EnsemblGenome=MTR_3g049070\|UniProtKB=G7IZZ4	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr10_16440\|UniProtKB=A0A2I4F971	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_6G422800\|UniProtKB=A0A0A0KHX9	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_3G170000\|UniProtKB=M5X5D3	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_140479\|UniProtKB=D8QRC4	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_171977\|UniProtKB=D8RJH8	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c18_4810\|UniProtKB=A0A2K1IZY5	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c19_12930\|UniProtKB=A0A2K1IY81	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0116s0052\|UniProtKB=A0A2R6WB43	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0090s0056\|UniProtKB=A0A2R6WHJ8	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_000020310\|UniProtKB=A0A1Y1HKK6	Klebsormidium nitens	O