PANTHER Gene Information

Gene Symbol(s):

arx-3

Organism:

Caenorhabditis elegans

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Gene Name:

Actin-related protein 2_3 complex subunit

Gene ID:

WBGene00000201

Protein ID:

A0A3P6PCS5

Persistent Id:

PTN000076285

Alternate Ids:

WBGene00000201(WormBase)	CE52951(WormBase_PRO)
WBGene00000201(Ensembl)	A0A3P6PCS5(Synonym)
BX284603(EMBL)	VDJ63192(EMBL-CDS)
Y79H2A.6b(WormBase_TRS)	A0A3P6PCS5_CAEEL(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 (PTHR10709)
PANTHER Subfamily:	ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT (PTHR10709:SF2)
PANTHER GO-slim Molecular Function:	actin filament binding
PANTHER GO-slim Biological Process:	Arp2/3 complex-mediated actin nucleation
PANTHER GO-slim Cellular Component:	Arp2/3 protein complex
PANTHER protein class:	actin or actin-binding cytoskeletal protein

Pathway Categories:

Inflammation mediated by chemokine and cytokine signaling pathway

Actin related protein 2/3 complex

Integrin signalling pathway

Actin related protein 2/3 complex

Huntington disease

Actin related protein 2/3 complex

Cytoskeletal regulation by Rho GTPase

Actin related protein 2/3 complex

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	actin filament binding, actin binding
GO BP Complete:	Arp2/3 complex-mediated actin nucleation, actin cytoskeleton organization
GO CC Complete:	cytoskeleton, cytoplasm, actin cytoskeleton, Arp2/3 protein complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Signal Transduction, Innate Immune System, Signaling by Rho GTPases, RHO GTPases Activate WASPs and WAVEs, Nervous system development, Developmental Biology, Vesicle-mediated transport, Membrane Trafficking, Fcgamma receptor (FCGR) dependent phagocytosis, EPH-Ephrin signaling, Clathrin-mediated endocytosis, Regulation of actin dynamics for phagocytic cup formation, EPHB-mediated forward signaling, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Axon guidance, RHO GTPase Effectors, Immune System

Orthologs

ID	Organism	Type
HUMAN\|HGNC=704\|UniProtKB=O15143	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000019449.5\|UniProtKB=H2QV01	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000013186.3\|UniProtKB=G3RBK8	Gorilla gorilla gorilla	O
MOUSE\|MGI=MGI=1343142\|UniProtKB=Q9WV32	Mus musculus	O
RAT\|RGD=2155\|UniProtKB=O88656	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000020684.4\|UniProtKB=A0A3Q1LGG1	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000046248\|UniProtKB=Q58CQ2	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000007625.5\|UniProtKB=B5APU6	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000024991.4\|UniProtKB=A0A3Q2HCF8	Equus caballus	O
CANLF\|Ensembl=ENSCAFG00845003541.1\|UniProtKB=A0A8I3MVD4	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000001316.4\|UniProtKB=F7BE06	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000007725.4\|UniProtKB=F6QT91	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010021362.1\|UniProtKB=A0A8V0ZJA4	Gallus gallus	O
XENLA\|Gene=arpc1b.L\|UniProtKB=A0A8J1LQP8	Xenopus laevis	O
XENLA\|Gene_ORFName=XELAEV_18045069mg\|UniProtKB=Q7ZXD5	Xenopus laevis	O
XENLA\|Gene_ORFName=XELAEV_18047442mg\|UniProtKB=Q6GNU1	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-490410\|UniProtKB=Q6DF56	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000009068.2\|UniProtKB=A0A3B3H8R8	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030131-7414\|UniProtKB=Q7T372	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000004536.1\|UniProtKB=W5MAL4	lepisosteus oculatus	O
XENLA\|Gene=LOC108701201\|UniProtKB=A0A1L8EUX9	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000017356.2\|UniProtKB=H2MSH0	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040625-80\|UniProtKB=A9JRP8	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000012417.1\|UniProtKB=W5N3T2	lepisosteus oculatus	LDO
PANTR\|Ensembl=ENSPTRG00000051667.1\|UniProtKB=A0A2I3TQ84	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000039925.1\|UniProtKB=A0A2I2YC68	Gorilla gorilla gorilla	O
PANTR\|Ensembl=ENSPTRG00000050251.1\|UniProtKB=A0A2I3T7D9	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000037353.1\|UniProtKB=A0A2I2YDG6	Gorilla gorilla gorilla	O
HUMAN\|HGNC=703\|UniProtKB=Q92747	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000033819.3\|UniProtKB=H2QV00	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000039217.1\|UniProtKB=G3R1E2	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000001458.4\|UniProtKB=H9FNS7	Macaca mulatta	O
MOUSE\|MGI=MGI=1928896\|UniProtKB=Q9R0Q6	Mus musculus	O
RAT\|RGD=620834\|UniProtKB=Q99PD4	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000049440.1\|UniProtKB=A0A3Q1NMB5	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000004242\|UniProtKB=Q1JP79	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000007609.5\|UniProtKB=F1REX9	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000050899.1\|UniProtKB=A0A9L0S565	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000015065.6\|UniProtKB=M3WLV8	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845003616.1\|UniProtKB=A0A8I3MPK0	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000048722.1\|UniProtKB=A0A5F8G810	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000016729.3\|UniProtKB=A0A5F8HHQ2	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000001303.4\|UniProtKB=F7BZM9	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000007724.4\|UniProtKB=F6QTB5	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010021325.1\|UniProtKB=A0A8V0ZJ54	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000012777.4\|UniProtKB=H9GJ97	Anolis carolinensis	O
XENLA\|Gene_ORFName=XELAEV_18047443mg\|UniProtKB=Q8AVT9	Xenopus laevis	O
XENLA\|Gene_ORFName=XELAEV_18045070mg\|UniProtKB=A0A1L8EXB5	Xenopus laevis	O
XENLA\|Gene=arpc1a.S\|UniProtKB=A0A8J0U071	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-6034682\|UniProtKB=Q28I17	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000009096.2\|UniProtKB=H2LZ39	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040116-1\|UniProtKB=Q7ZUQ0	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000004549.1\|UniProtKB=W5MAM8	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000004481.3\|UniProtKB=F6TEZ1	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118429270\|UniProtKB=A0A9J7M8V7	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC581455\|UniProtKB=A0A7M7HPN8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC585909\|UniProtKB=A0A7M7NSH7	Strongylocentrotus purpuratus	LDO
CAEBR\|Gene_ORFName=CBG18174\|UniProtKB=A8XT67	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00274703\|UniProtKB=A0A2A6CY92	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00274999\|UniProtKB=A0A2A6BP68	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0001961\|UniProtKB=O97182	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP008908\|UniProtKB=Q7PWN2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC000050\|UniProtKB=D6WDC6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_300535\|UniProtKB=E9HDB8	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW011129\|UniProtKB=B7Q740	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG185993\|UniProtKB=T1FNJ1	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g236117\|UniProtKB=A7SZA7	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG60814\|UniProtKB=B3S988	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_35994\|UniProtKB=A9UR80	Monosiga brevicollis	LDO
YEAST\|SGD=S000000438\|UniProtKB=P38328	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFL022W\|UniProtKB=Q754U3	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000175984\|UniProtKB=A0A1D8PT60	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_B17380g\|UniProtKB=Q6CE98	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_05778\|UniProtKB=Q5B102	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_6G06500\|UniProtKB=Q4WNG0	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU02781\|UniProtKB=Q7SE13	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_04510\|UniProtKB=A7EGR8	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_03354\|UniProtKB=Q0UY10	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC14C8.06\|UniProtKB=P78774	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02075\|UniProtKB=B6JZN3	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNF00940\|UniProtKB=Q5KFQ5	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_05906\|UniProtKB=A0A0D1DQB3	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_02224\|UniProtKB=E3JXI8	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_18271\|UniProtKB=F4NT44	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_045000\|UniProtKB=C4LTB5	Entamoeba histolytica	LDO
ENTH1\|EnsemblGenome=CL6EHI_094120\|UniProtKB=C4LYJ9	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0277825\|UniProtKB=O96622	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_95056\|UniProtKB=F0ZRS0	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_18_0920\|UniProtKB=Q4QDV0	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb10.389.0270\|UniProtKB=Q388S8	Trypanosoma brucei	LDO
TRIV3\|Gene_ORFName=TVAG_035180\|UniProtKB=A2DAJ2	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_1118800\|UniProtKB=Q8IIH9	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00010112001\|UniProtKB=A0CSS3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00006678001\|UniProtKB=A0C9A5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00002218001\|UniProtKB=A0DGC2	Paramecium tetraurelia	LDO
PHYRM\|Gene=H3GNT1_PHYRM\|UniProtKB=H3GNT1	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_16g648100v5\|UniProtKB=A0A2K3CSQ7	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00039p00197260\|UniProtKB=U5CRM6	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_15G01330\|UniProtKB=A0A0K9PV25	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma11_g07370\|UniProtKB=A0A804L5A3	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_017523mg\|UniProtKB=K3YTC8	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G345400\|UniProtKB=A0A194YU89	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb258930\|UniProtKB=C4IZE9	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb191400\|UniProtKB=B6TA39	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os02g0817200\|UniProtKB=Q6K699	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g55390v3\|UniProtKB=I1IDX5	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0629710\|UniProtKB=A0A8I6YX20	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6B02G432000\|UniProtKB=A0A3B6PTP7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCSU02G081300\|UniProtKB=A0A341ZB41	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G377800\|UniProtKB=A0A3B6QKZ3	Triticum aestivum	LDO
NELNU\|Gene=LOC104608427\|UniProtKB=A0A1U8QAN3	Nelumbo nucifera	O
NELNU\|Gene=LOC104609009\|UniProtKB=A0A1U8AYS2	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110783720\|UniProtKB=A0A9R0I6W9	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr16g0756401\|UniProtKB=A0A251S1U5	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C400178040\|UniProtKB=A0A9R1VSC6	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a008285mg\|UniProtKB=A0A022S272	Erythranthe guttata	LDO
SOLLC\|EnsemblGenome=Solyc05g006470.3\|UniProtKB=A0A3Q7GDR2	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107784652\|UniProtKB=A0A1S3ZA87	Nicotiana tabacum	O
TOBAC\|Gene=LOC107832594\|UniProtKB=A0A1S4DR85	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi12g02215\|UniProtKB=E0CTY0	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_K01189\|UniProtKB=A0A058ZZP8	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_A05P14760.1\|UniProtKB=A0A078FF85	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C03P20380.1\|UniProtKB=A0A078GBX8	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00043385001\|UniProtKB=A0A078GYH3	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C04P19760.1\|UniProtKB=A0A078ICQ8	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra021676\|UniProtKB=M4DYT0	Brassica campestris	O
BRACM\|EnsemblGenome=Bra022818\|UniProtKB=M4E218	Brassica campestris	LDO
ARATH\|TAIR=locus=2042491\|UniProtKB=Q9SJW6	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2052871\|UniProtKB=O80856	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107896882\|UniProtKB=A0A1U8IMN2	Gossypium hirsutum	O
GOSHI\|Gene=LOC107914491\|UniProtKB=A0A1U8K8T5	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_001800\|UniProtKB=A0A061DJX7	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g016982mg\|UniProtKB=A0A067EU28	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_014G141700v3\|UniProtKB=B9IA44	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_02G087100\|UniProtKB=A0A2C9WC45	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_01G129200\|UniProtKB=A0A251LR00	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0540370\|UniProtKB=B9SIS1	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_10G216300\|UniProtKB=I1LD74	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_18G103800\|UniProtKB=I1N0U4	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_08G311700\|UniProtKB=K7LA18	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_3g049070\|UniProtKB=G7IZZ4	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr10_16440\|UniProtKB=A0A2I4F971	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_6G422800\|UniProtKB=A0A0A0KHX9	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_3G170000\|UniProtKB=M5X5D3	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_140479\|UniProtKB=D8QRC4	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_171977\|UniProtKB=D8RJH8	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c18_4810\|UniProtKB=A0A2K1IZY5	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c19_12930\|UniProtKB=A0A2K1IY81	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0116s0052\|UniProtKB=A0A2R6WB43	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0090s0056\|UniProtKB=A0A2R6WHJ8	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000020310\|UniProtKB=A0A1Y1HKK6	Klebsormidium nitens	LDO