PANTHER Gene Information

Gene Symbol(s):

ChAT

Organism:

Drosophila melanogaster

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Gene Name:

Choline O-acetyltransferase

Gene ID:

FBgn0000303

Protein ID:

P07668

Persistent Id:

PTN000502059

Alternate Ids:

FBgn0000303(FlyBase)	2.3.1.6 {ECO:0000269\|PubMed:1851526}(EC)
ChAT{ECO:0000303\|PubMed:1717651,ECO:0000312\|FlyBase:FBgn0000303}(Symbol)	CHOACTase {ECO:0000305}(Synonym)
AAA28406(EMBL-CDS)	M63724(EMBL)
Q8MQR2(AltAccession)	CLAT_DROME(UniProtKB-ID)
FBgn0000303(Ensembl)	4803855(GI)
42249(GeneID)
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PANTHER Classification

PANTHER Family:	CARNITINE O-ACYLTRANSFERASE (PTHR22589)
PANTHER Subfamily:	CHOLINE O-ACETYLTRANSFERASE (PTHR22589:SF14)
PANTHER GO-slim Molecular Function:	O-acyltransferase activity acetyltransferase activity
PANTHER GO-slim Biological Process:	nitrogen compound metabolic process neuromuscular synaptic transmission organic substance biosynthetic process
PANTHER GO-slim Cellular Component:	neuron projection cytoplasm
PANTHER protein class:	acyltransferase

Pathway Categories:

Nicotinic acetylcholine receptor signaling pathway

choline acetyltransferase

Muscarinic acetylcholine receptor 2 and 4 signaling pathway

choline acetyltransferase

Muscarinic acetylcholine receptor 1 and 3 signaling pathway

choline acetyltransferase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	acyltransferase activity, choline O-acetyltransferase activity
GO BP Complete:	acetylcholine biosynthetic process, neuromuscular synaptic transmission
GO CC Complete:	nucleus, cytoplasm, terminal bouton, cytosol, neuron projection

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Neuronal System, Transmission across Chemical Synapses, Metabolism, Phospholipid metabolism, Synthesis of PC, Glycerophospholipid biosynthesis, Neurotransmitter release cycle, Metabolism of lipids, Acetylcholine Neurotransmitter Release Cycle

Orthologs

ID	Organism	Type
HUMAN\|HGNC=1912\|UniProtKB=P28329	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000002489.5\|UniProtKB=H2RAF8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015179.3\|UniProtKB=G3RGQ8	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000004692.4\|UniProtKB=F6RM01	Macaca mulatta	LDO
MOUSE\|MGI=MGI=88392\|UniProtKB=Q03059	Mus musculus	LDO
RAT\|RGD=1304627\|UniProtKB=P32738	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000016814.6\|UniProtKB=F1MLQ5	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000010392.3\|UniProtKB=A0A2C9F3D4	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00025075663\|UniProtKB=P13222	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000021611.3\|UniProtKB=A0A3Q2GY83	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000002065.6\|UniProtKB=A0A2I2U4U6	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845021769.1\|UniProtKB=A0A8I3PDE8	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000002547.4\|UniProtKB=F7ALU3	Monodelphis domestica	LDO
CHICK\|Gene=CHAT\|UniProtKB=Q90YJ9	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010010839.1\|UniProtKB=F1P393	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000015249.3\|UniProtKB=H9GM80	Anolis carolinensis	LDO
XENLA\|Gene=chat.S\|UniProtKB=A0A8J1LDM7	Xenopus laevis	O
XENLA\|Gene=chat.L\|UniProtKB=A0A8J0TA63	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-984174\|UniProtKB=A0A8J0QJ80	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000009452.2\|UniProtKB=H2M0C1	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000006943.2\|UniProtKB=A0A3B3I9Z8	Oryzias latipes	LDO
DANRE\|Gene=chata\|UniProtKB=A0A8M9Q9G1	Danio rerio	LDO
DANRE\|ZFIN=ZDB-GENE-140429-2\|UniProtKB=V9Z677	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-080102-2\|UniProtKB=B2ZGJ1	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000005657.1\|UniProtKB=W5MEN0	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000002571.3\|UniProtKB=F6UEZ5	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118412577\|UniProtKB=A0A9J7MKW3	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC574696\|UniProtKB=A0A7M7NDQ0	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00000481\|UniProtKB=P32756	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00030124\|UniProtKB=A8X694	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00101190\|UniProtKB=A0A2A6BY29	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP002370\|UniProtKB=A0A1S4GEW3	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC032116\|UniProtKB=A0A139WMW1	Tribolium castaneum	LDO
DAPPU\|Gene_ORFName=DAPPUDRAFT_45346\|UniProtKB=E9G3N0	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW022171\|UniProtKB=B7QD11	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG84274\|UniProtKB=T1G5G8	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g416\|UniProtKB=A7T6K7	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g95805\|UniProtKB=A7RW65	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g163430\|UniProtKB=A7RW66	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g203043\|UniProtKB=A7RW64	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG28550\|UniProtKB=B3S3X0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG31807\|UniProtKB=B3S9R5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG31498\|UniProtKB=B3S997	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG21860\|UniProtKB=B3RPC2	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG21707\|UniProtKB=B3RPC1	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG21352\|UniProtKB=B3RPE6	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG33379\|UniProtKB=B3SCI6	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG20587\|UniProtKB=B3RP88	Trichoplax adhaerens	O
CRYNJ\|EnsemblGenome=CNL05760\|UniProtKB=Q5K8G7	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_11660\|UniProtKB=A0A0D1E790	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_07182\|UniProtKB=E3K9Q6	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_35927\|UniProtKB=F4PAR2	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_10147\|UniProtKB=F4NY05	Batrachochytrium dendrobatidis	O
YEAST\|SGD=S000004506\|UniProtKB=P32796	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AAR124C\|UniProtKB=Q75EF7	Eremothecium gossypii	O
CANAL\|CGD=CAL0000184947\|UniProtKB=Q5AMQ5	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_B10340g\|UniProtKB=Q6CF46	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_10447\|UniProtKB=C8V468	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_06279\|UniProtKB=C8V1G3	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_2G12530\|UniProtKB=Q4X0R8	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU08002\|UniProtKB=Q7SAN8	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_13339\|UniProtKB=A7F6V9	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_05975\|UniProtKB=Q0UQI9	Phaeosphaeria nodorum	O
CRYNJ\|EnsemblGenome=CNA05200\|UniProtKB=Q5KNV3	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_00789\|UniProtKB=A0A0D1EAZ4	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_04365\|UniProtKB=E3K240	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_04359\|UniProtKB=E3K234	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_04366\|UniProtKB=E3K241	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_13099\|UniProtKB=F4P876	Batrachochytrium dendrobatidis	O
THAPS\|EnsemblGenome=THAPSDRAFT_31762\|UniProtKB=B8BTN0	Thalassiosira pseudonana	O
PHYRM\|Gene=H3G9Q7_PHYRM\|UniProtKB=H3G9Q7	Phytophthora ramorum	O