PANTHER Gene Information

Gene Symbol(s):

Ae2

Organism:

Drosophila melanogaster

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Gene Name:

Anion exchange protein

Gene ID:

FBgn0036043

Protein ID:

Q9VT48

Persistent Id:

PTN000155499

Alternate Ids:

AAF50207(EMBL-CDS)	FBpp0076048(Ensembl_PRO)
FBgn0036043(Ensembl)	39147(GeneID)
NP_729546(refSeq)	24661908(GI)
Q9VT48(Synonym)	AE014296(EMBL)
Q9VT48_DROME(UniProtKB-ID)	FBtr0076321(Ensembl_TRS)
FBgn0036043(FlyBase)
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PANTHER Classification

PANTHER Family:	ANION EXCHANGE PROTEIN (PTHR11453)
PANTHER Subfamily:	ANION EXCHANGE PROTEIN (PTHR11453:SF47)
PANTHER GO-slim Molecular Function:	transmembrane transporter activity
PANTHER GO-slim Biological Process:	transmembrane transport organic anion transport monoatomic ion homeostasis
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	secondary carrier transporter

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	transmembrane transporter activity, monoatomic anion transmembrane transporter activity, solute:inorganic anion antiporter activity
GO BP Complete:	regulation of intracellular pH, transmembrane transport, intracellular pH reduction, monoatomic anion transport, bicarbonate transport
GO CC Complete:	membrane, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

SLC-mediated transmembrane transport, Bicarbonate transporters, Transport of inorganic cations/anions and amino acids/oligopeptides, Erythrocytes take up carbon dioxide and release oxygen, Erythrocytes take up oxygen and release carbon dioxide, O2/CO2 exchange in erythrocytes, Transport of small molecules

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11027\|UniProtKB=P02730	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000009270.6\|UniProtKB=H2QD68	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010736.3\|UniProtKB=G3R5A5	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000017100.4\|UniProtKB=F7H5B9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=109393\|UniProtKB=P04919	Mus musculus	LDO
RAT\|RGD=3710\|UniProtKB=P23562	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000001610.6\|UniProtKB=F6QPG2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000017358.6\|UniProtKB=K7GR72	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000000527.4\|UniProtKB=Q2Z1P9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000003051.6\|UniProtKB=M3VZM4	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845008600.1\|UniProtKB=Q2Z1P8	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000011613.4\|UniProtKB=A0A5F8G2Q0	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000002629.3\|UniProtKB=F6SKS8	Ornithorhynchus anatinus	LDO
CHICK\|Gene=SLC4A1\|UniProtKB=P15575	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010024885.1\|UniProtKB=A0A8V1A0K9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000017228.4\|UniProtKB=G1KTP9	Anolis carolinensis	LDO
XENLA\|Gene=slc4a1.L\|UniProtKB=A0A1L8ESA4	Xenopus laevis	LDO
XENLA\|Gene=slc4a1.S\|UniProtKB=A0A8J0TYW1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-986935\|UniProtKB=A0A6I8QVY8	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000002557.2\|UniProtKB=A0A3B3HN20	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000005495.2\|UniProtKB=H2LLK3	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-010525-1\|UniProtKB=Q7ZZJ7	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-110215-2\|UniProtKB=D1FTM8	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000012065.1\|UniProtKB=W5N2L3	lepisosteus oculatus	LDO
HUMAN\|HGNC=11029\|UniProtKB=P48751	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000012966.6\|UniProtKB=H2QJH6	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000005518.3\|UniProtKB=G3QRZ0	Gorilla gorilla gorilla	O
MOUSE\|MGI=MGI=109350\|UniProtKB=P16283	Mus musculus	O
RAT\|RGD=3712\|UniProtKB=P23348	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000014975.6\|UniProtKB=E1BKK3	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000022846.3\|UniProtKB=I3LJ89	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000010982.4\|UniProtKB=A0A5F5PEV2	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000006669.6\|UniProtKB=A0A2I2UQ82	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845030591.1\|UniProtKB=A0A8I3Q4Q8	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000015043.4\|UniProtKB=F7G5B5	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000038560.1\|UniProtKB=A0A6I8P317	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010021348.1\|UniProtKB=E1C314	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000014380.4\|UniProtKB=G1KQ20	Anolis carolinensis	O
XENLA\|Gene=slc4a3.L\|UniProtKB=A0A1L8EVH4	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-996901\|UniProtKB=A0A7D9NL51	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000030477.1\|UniProtKB=A0A3B3H3W9	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-141006-1\|UniProtKB=A0A096X8J7	Danio rerio	O
DANRE\|Gene=slc4a3\|UniProtKB=A0A8M3AWC1	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000009239.1\|UniProtKB=W5MSB6	lepisosteus oculatus	O
HUMAN\|HGNC=11028\|UniProtKB=P04920	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000019873.6\|UniProtKB=H2QVM4	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000016887.3\|UniProtKB=A0A2I2Z7D0	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000020456.4\|UniProtKB=G7MNG7	Macaca mulatta	O
MOUSE\|MGI=MGI=109351\|UniProtKB=P13808	Mus musculus	O
RAT\|RGD=3711\|UniProtKB=P23347	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000011226.6\|UniProtKB=A0A3Q1M051	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000021475.4\|UniProtKB=A0A287AI58	Sus scrofa	O
HORSE\|Gene=SLC4A2\|UniProtKB=Q6SJP2	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000024958.4\|UniProtKB=F6QU34	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000013197.5\|UniProtKB=M3WPW8	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845009099.1\|UniProtKB=A0A8I3NMT2	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000004225.4\|UniProtKB=F6UBP3	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000049025.1\|UniProtKB=A0A6I8PIW4	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010027162.1\|UniProtKB=A0A8V1A2L0	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000005372.3\|UniProtKB=H9GAE4	Anolis carolinensis	O
XENLA\|Gene=slc4a2.S\|UniProtKB=A0A1L8FPZ6	Xenopus laevis	O
XENLA\|Gene=LOC108704633\|UniProtKB=A0A8J1KZK5	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000048904\|UniProtKB=A0A803K264	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000006900.2\|UniProtKB=A0A3B3I832	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000012164.2\|UniProtKB=H2M9P2	Oryzias latipes	O
DANRE\|Gene=slc4a2a\|UniProtKB=A0A8M9PZ09	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-030429-14\|UniProtKB=A9NIM6	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000010245.1\|UniProtKB=W5MW07	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000021742.1\|UniProtKB=F7BGU9	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000003422.3\|UniProtKB=F6XL93	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118406013\|UniProtKB=A0A9J7K971	Branchiostoma floridae	O
BRAFL\|Gene=LOC118405285\|UniProtKB=A0A9J7KIH3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118405237\|UniProtKB=A0A9J7HNI3	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC588892\|UniProtKB=A0A7M7N3L9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC587119\|UniProtKB=A0A7M7N5M7	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00019844\|UniProtKB=Q58QG8	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG10883\|UniProtKB=A8XC73	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00094941\|UniProtKB=A0A2A6BXS9	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP006968\|UniProtKB=Q7PT77	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP006115\|UniProtKB=A0A1S4GRA2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC032346\|UniProtKB=A0A139WM41	Tribolium castaneum	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g135965\|UniProtKB=A7SWX4	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g91031\|UniProtKB=A7RRK7	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG22844\|UniProtKB=B3RRA7	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG54168\|UniProtKB=B3RRA8	Trichoplax adhaerens	LDO
TRIV3\|Gene_ORFName=TVAG_055340\|UniProtKB=A2ETK2	Trichomonas vaginalis	O
THAPS\|EnsemblGenome=THAPSDRAFT_270361\|UniProtKB=B8BQB7	Thalassiosira pseudonana	O
PHYPA\|EnsemblGenome=Pp3c14_8980\|UniProtKB=A0A7I4ATU0	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0052s0055\|UniProtKB=A0A2R6WWM0	Marchantia polymorpha	O