PANTHER Gene Information

Gene Symbol(s):

SLC4A1

Organism:

Equus caballus

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Gene Name:

Anion exchange protein

Gene ID:

ENSECAG00000000527.4

Protein ID:

Q2Z1P9

Persistent Id:

PTN001351442

Alternate Ids:

100009691(GeneID)	ENSECAP00000001508(Ensembl_PRO)
BAE48711(EMBL-CDS)	NM_001081788(refSeq)
ENSECAG00000000527(Ensembl)	126352483(GI)
Q2Z1P9_HORSE(UniProtKB-ID)	AB242565(EMBL)
ENSECAT00000002131(Ensembl_TRS)	Q2Z1P9(Synonym)
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PANTHER Classification

PANTHER Family:	ANION EXCHANGE PROTEIN (PTHR11453)
PANTHER Subfamily:	BAND 3 ANION TRANSPORT PROTEIN (PTHR11453:SF12)
PANTHER GO-slim Molecular Function:	organic anion transmembrane transporter activity
PANTHER GO-slim Biological Process:	transmembrane transport organic anion transport regulation of intracellular pH
PANTHER GO-slim Cellular Component:	basolateral plasma membrane
PANTHER protein class:	secondary carrier transporter

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	protein homodimerization activity, antiporter activity, ankyrin binding, chloride:bicarbonate antiporter activity, monoatomic anion transmembrane transporter activity, hemoglobin binding, solute:inorganic anion antiporter activity, chloride transmembrane transporter activity, bicarbonate transmembrane transporter activity
GO BP Complete:	transmembrane transport, chloride transmembrane transport, pH elevation, erythrocyte development, blood coagulation, monoatomic anion transport, chloride transport, negative regulation of glycolytic process through fructose-6-phosphate, monoatomic ion transport, regulation of intracellular pH, plasma membrane phospholipid scrambling, negative regulation of urine volume, bicarbonate transport, protein localization to plasma membrane
GO CC Complete:	Z disc, ankyrin-1 complex, membrane, basolateral plasma membrane, plasma membrane, cytoplasmic side of plasma membrane, cortical cytoskeleton

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11027\|UniProtKB=P02730	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000009270.6\|UniProtKB=H2QD68	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010736.3\|UniProtKB=G3R5A5	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000017100.4\|UniProtKB=F7H5B9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=109393\|UniProtKB=P04919	Mus musculus	LDO
RAT\|RGD=3710\|UniProtKB=P23562	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000001610.6\|UniProtKB=F6QPG2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000017358.6\|UniProtKB=K7GR72	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000003051.6\|UniProtKB=M3VZM4	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845008600.1\|UniProtKB=Q2Z1P8	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000011613.4\|UniProtKB=A0A5F8G2Q0	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000002629.3\|UniProtKB=F6SKS8	Ornithorhynchus anatinus	LDO
CHICK\|Gene=SLC4A1\|UniProtKB=P15575	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010024885.1\|UniProtKB=A0A8V1A0K9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000017228.4\|UniProtKB=G1KTP9	Anolis carolinensis	LDO
XENLA\|Gene=slc4a1.L\|UniProtKB=A0A1L8ESA4	Xenopus laevis	LDO
XENLA\|Gene=slc4a1.S\|UniProtKB=A0A8J0TYW1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-986935\|UniProtKB=A0A6I8QVY8	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000002557.2\|UniProtKB=A0A3B3HN20	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000005495.2\|UniProtKB=H2LLK3	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-010525-1\|UniProtKB=Q7ZZJ7	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-110215-2\|UniProtKB=D1FTM8	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000012065.1\|UniProtKB=W5N2L3	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000021742.1\|UniProtKB=F7BGU9	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000003422.3\|UniProtKB=F6XL93	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118406013\|UniProtKB=A0A9J7K971	Branchiostoma floridae	O
BRAFL\|Gene=LOC118405285\|UniProtKB=A0A9J7KIH3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118405237\|UniProtKB=A0A9J7HNI3	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC588892\|UniProtKB=A0A7M7N3L9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC587119\|UniProtKB=A0A7M7N5M7	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00019844\|UniProtKB=Q58QG8	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG10883\|UniProtKB=A8XC73	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00094941\|UniProtKB=A0A2A6BXS9	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0036043\|UniProtKB=Q9VT48	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP006968\|UniProtKB=Q7PT77	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP006115\|UniProtKB=A0A1S4GRA2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC032346\|UniProtKB=A0A139WM41	Tribolium castaneum	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g135965\|UniProtKB=A7SWX4	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g91031\|UniProtKB=A7RRK7	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG22844\|UniProtKB=B3RRA7	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG54168\|UniProtKB=B3RRA8	Trichoplax adhaerens	LDO
TRIV3\|Gene_ORFName=TVAG_055340\|UniProtKB=A2ETK2	Trichomonas vaginalis	O
THAPS\|EnsemblGenome=THAPSDRAFT_270361\|UniProtKB=B8BQB7	Thalassiosira pseudonana	O
PHYPA\|EnsemblGenome=Pp3c14_8980\|UniProtKB=A0A7I4ATU0	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0052s0055\|UniProtKB=A0A2R6WWM0	Marchantia polymorpha	O