PANTHER Gene Information

Gene Symbol(s):

PRL

Organism:

Felis catus

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Gene Name:

Prolactin

Gene ID:

ENSFCAG00000015035

Protein ID:

P46403

Persistent Id:

PTN001686479

Alternate Ids:

NM_001043341(refSeq)	751517(GeneID)
ENSFCAP00000013943(Ensembl_PRO)	PRL_FELCA(UniProtKB-ID)
PRL(Symbol)	PRL(Synonym)
AAA67295(EMBL-CDS)	ENSFCAT00000015037(Ensembl_TRS)
ENSFCAG00000015035(Ensembl)	U25974(EMBL)
112807242(GI)
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PANTHER Classification

PANTHER Family:	SOMATOTROPIN,PROLACTIN (PTHR11417)
PANTHER Subfamily:	PROLACTIN (PTHR11417:SF5)
PANTHER GO-slim Molecular Function:	hormone activity
PANTHER GO-slim Biological Process:	positive regulation of cell population proliferation positive regulation of receptor signaling pathway via JAK-STAT response to nutrient levels
PANTHER GO-slim Cellular Component:	extracellular space
PANTHER protein class:	peptide hormone

Pathway Categories:

Gonadotropin-releasing hormone receptor pathway

Prolactin

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	metal ion binding, hormone activity, prolactin receptor binding
GO BP Complete:	mammary gland development, signal transduction, prolactin signaling pathway, positive regulation of canonical NF-kappaB signal transduction, female pregnancy, negative regulation of endothelial cell proliferation, cell surface receptor signaling pathway, lactation, positive regulation of miRNA transcription, positive regulation of lactation, response to nutrient levels, positive regulation of receptor signaling pathway via JAK-STAT
GO CC Complete:	extracellular space, extracellular region

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9445\|UniProtKB=P01236	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000017768.4\|UniProtKB=H2QSD1	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000001363.3\|UniProtKB=G3QG92	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000020646.4\|UniProtKB=G7MQU0	Macaca mulatta	LDO
MACMU\|Gene=PRL\|UniProtKB=P55151	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1206571\|UniProtKB=O54831	Mus musculus	O
RAT\|RGD=1359651\|UniProtKB=A0A8I6AU34	Rattus norvegicus	O
RAT\|RGD=620035\|UniProtKB=Q9R006	Rattus norvegicus	O
MOUSE\|MGI=MGI=1861444\|UniProtKB=Q9DAZ2	Mus musculus	O
RAT\|RGD=620118\|UniProtKB=Q9JKL9	Rattus norvegicus	O
MOUSE\|MGI=MGI=2660935\|UniProtKB=F6R3P9	Mus musculus	O
MOUSE\|MGI=MGI=97606\|UniProtKB=P18121	Mus musculus	O
MOUSE\|MGI=MGI=2660938\|UniProtKB=A0A0M6L0J6	Mus musculus	O
RAT\|RGD=2427\|UniProtKB=P21702	Rattus norvegicus	O
RAT\|RGD=2428\|UniProtKB=P34207	Rattus norvegicus	O
MOUSE\|MGI=MGI=1914560\|UniProtKB=Q9CQ58	Mus musculus	O
RAT\|RGD=619862\|UniProtKB=Q920I0	Rattus norvegicus	O
MOUSE\|MGI=MGI=1914755\|UniProtKB=Q9CRB5	Mus musculus	O
RAT\|RGD=1593943\|UniProtKB=M0R967	Rattus norvegicus	O
MOUSE\|MGI=MGI=1206579\|UniProtKB=O35257	Mus musculus	O
RAT\|RGD=3405\|UniProtKB=P24800	Rattus norvegicus	O
MOUSE\|MGI=MGI=1921438\|UniProtKB=Q9DAS4	Mus musculus	O
MOUSE\|MGI=MGI=1332225\|UniProtKB=Q9DAY2	Mus musculus	O
RAT\|RGD=620116\|UniProtKB=P33580	Rattus norvegicus	O
RAT\|RGD=708348\|UniProtKB=P33579	Rattus norvegicus	O
RAT\|RGD=620115\|UniProtKB=P33578	Rattus norvegicus	O
MOUSE\|MGI=MGI=1206587\|UniProtKB=O35256	Mus musculus	O
RAT\|RGD=3404\|UniProtKB=P09320	Rattus norvegicus	O
MOUSE\|MGI=MGI=97607\|UniProtKB=P09586	Mus musculus	O
RAT\|RGD=2429\|UniProtKB=P09321	Rattus norvegicus	O
MOUSE\|MGI=MGI=1206572\|UniProtKB=O54830	Mus musculus	O
RAT\|RGD=7695636\|UniProtKB=A0A8I6AW68	Rattus norvegicus	O
MOUSE\|MGI=MGI=894281\|UniProtKB=O54832	Mus musculus	O
MOUSE\|MGI=MGI=1920494\|UniProtKB=Q9DAV8	Mus musculus	O
RAT\|RGD=2516\|UniProtKB=Q4QRA1	Rattus norvegicus	O
MOUSE\|MGI=MGI=1341833\|UniProtKB=P04768	Mus musculus	O
MOUSE\|MGI=MGI=1858413\|UniProtKB=Q9JLV9	Mus musculus	O
MOUSE\|MGI=MGI=97618\|UniProtKB=P04095	Mus musculus	O
MOUSE\|MGI=MGI=3649927\|UniProtKB=Q5SVL9	Mus musculus	O
RAT\|RGD=1562878\|UniProtKB=Q1KZI0	Rattus norvegicus	O
MOUSE\|MGI=MGI=97619\|UniProtKB=P04769	Mus musculus	O
RAT\|RGD=621307\|UniProtKB=Q9R005	Rattus norvegicus	O
MOUSE\|MGI=MGI=106332\|UniProtKB=Q9JII2	Mus musculus	O
RAT\|RGD=1583904\|UniProtKB=Q1KZI1	Rattus norvegicus	O
RAT\|RGD=620120\|UniProtKB=Q9JII4	Rattus norvegicus	O
MOUSE\|MGI=MGI=1922846\|UniProtKB=Q8CGZ9	Mus musculus	O
RAT\|RGD=708582\|UniProtKB=Q8CJ42	Rattus norvegicus	O
MOUSE\|MGI=MGI=1351649\|UniProtKB=Q9QUN5	Mus musculus	O
RAT\|RGD=69341\|UniProtKB=Q9QUL0	Rattus norvegicus	O
MOUSE\|MGI=MGI=1914250\|UniProtKB=Q78Y73	Mus musculus	O
RAT\|RGD=731250\|UniProtKB=A0A0G2JYV6	Rattus norvegicus	O
MOUSE\|MGI=MGI=1861446\|UniProtKB=Q9JHK0	Mus musculus	O
RAT\|RGD=620121\|UniProtKB=Q9JII3	Rattus norvegicus	O
MOUSE\|MGI=MGI=97762\|UniProtKB=P06879	Mus musculus	LDO
RAT\|RGD=3403\|UniProtKB=P01237	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000031640.4\|UniProtKB=F1N6S6	Bos taurus	O
BOVIN\|Gene=CSH1\|UniProtKB=P09611	Bos taurus	O
BOVIN\|Gene=PRP3\|UniProtKB=P12402	Bos taurus	O
BOVIN\|Gene=PRP2\|UniProtKB=P12401	Bos taurus	O
BOVIN\|Gene=PRP1\|UniProtKB=P05402	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000052064.1\|UniProtKB=A0A0M6L0P8	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000049869.1\|UniProtKB=E1BC34	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000006761.6\|UniProtKB=F1MYF0	Bos taurus	O
BOVIN\|Gene=PRP4\|UniProtKB=P18917	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000025314.5\|UniProtKB=Q2WGK0	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000036106.4\|UniProtKB=Q2WG99	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000025304.5\|UniProtKB=Q2WFM8	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000025302.5\|UniProtKB=Q2PEE7	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000038718.3\|UniProtKB=A0A0M6L0Q6	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000051382.1\|UniProtKB=A0A3Q1M6B7	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000049075.1\|UniProtKB=A4PBQ6	Bos taurus	O
BOVIN\|Gene=CSH2\|UniProtKB=P19159	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000015274\|UniProtKB=P01239	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000039721.3\|UniProtKB=A0A286ZMS9	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00005013825\|UniProtKB=P01238	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000000114.4\|UniProtKB=A0A9L0SHR2	Equus caballus	LDO
HORSE\|Gene=PRL\|UniProtKB=P12420	Equus caballus	LDO
CANLF\|Ensembl=ENSCAFG00845017595.1\|UniProtKB=E2RAF4	Canis lupus familiaris	LDO
MONDO\|Gene=PRL\|UniProtKB=O62819	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000011350.1\|UniProtKB=F6W2N8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000011127.4\|UniProtKB=F7DGX1	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010008082\|UniProtKB=P14676	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000002939.3\|UniProtKB=G1KBD7	Anolis carolinensis	LDO
XENLA\|Gene=prl.2.S\|UniProtKB=A0A8J0TBC1	Xenopus laevis	O
XENLA\|Gene=LOC108695906\|UniProtKB=A0A8J0T9Y6	Xenopus laevis	O
XENTR\|Gene=LOC100498019\|UniProtKB=A0A8J1JWY0	Xenopus tropicalis	O
XENTR\|Gene=LOC100497196\|UniProtKB=A0A8J1K137	Xenopus tropicalis	O
XENTR\|Ensembl=ENSXETG00000035107\|UniProtKB=A0A6I8RB89	Xenopus tropicalis	O
XENLA\|Gene=prl.1.S\|UniProtKB=Q56A64	Xenopus laevis	O
XENLA\|Gene=prl.1.L\|UniProtKB=Q6DJG3	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-482866\|UniProtKB=A4QNQ2	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000016928.2\|UniProtKB=H2MR01	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030513-1\|UniProtKB=Q569P7	Danio rerio	LDO