PANTHER Gene Information

Gene Symbol(s):

Prl8a2

Organism:

Rattus norvegicus

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Gene Name:

Growth hormone d12

Gene ID:

2516

Protein ID:

Q4QRA1

Persistent Id:

PTN000151895

Alternate Ids:

LM644205(EMBL)	XM_006253906(refSeq)
ENSRNOG00000017048(Ensembl)	Q4QRA1_RAT(UniProtKB-ID)
CDW51452(EMBL-CDS)	81918216(GI)
24315(GeneID)	Q4QRA1(Synonym)
2516(RGD)	ENSRNOT00000022923(Ensembl_TRS)
ENSRNOP00000022923(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	SOMATOTROPIN,PROLACTIN (PTHR11417)
PANTHER Subfamily:	DECIDUAL PRL-RELATED PROTEIN-RELATED (PTHR11417:SF16)
PANTHER GO-slim Molecular Function:	hormone activity cytokine receptor binding
PANTHER GO-slim Biological Process:	positive regulation of cell population proliferation multicellular organismal process positive regulation of receptor signaling pathway via JAK-STAT positive regulation of secretion regulation of body fluid levels animal organ development positive regulation of developmental process response to nutrient levels regulation of multicellular organismal development reproductive process positive regulation of multicellular organismal process
PANTHER GO-slim Cellular Component:	extracellular space
PANTHER protein class:	peptide hormone

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	hormone activity, prolactin receptor binding
GO BP Complete:	mammary gland development, female pregnancy, cell surface receptor signaling pathway, positive regulation of lactation, response to nutrient levels, positive regulation of receptor signaling pathway via JAK-STAT
GO CC Complete:	extracellular space

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9445\|UniProtKB=P01236	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000017768.4\|UniProtKB=H2QSD1	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000001363.3\|UniProtKB=G3QG92	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000020646.4\|UniProtKB=G7MQU0	Macaca mulatta	O
MACMU\|Gene=PRL\|UniProtKB=P55151	Macaca mulatta	O
MOUSE\|MGI=MGI=894281\|UniProtKB=O54832	Mus musculus	O
MOUSE\|MGI=MGI=1920494\|UniProtKB=Q9DAV8	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000031640.4\|UniProtKB=F1N6S6	Bos taurus	O
BOVIN\|Gene=CSH1\|UniProtKB=P09611	Bos taurus	O
BOVIN\|Gene=PRP3\|UniProtKB=P12402	Bos taurus	O
BOVIN\|Gene=PRP2\|UniProtKB=P12401	Bos taurus	O
BOVIN\|Gene=PRP1\|UniProtKB=P05402	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000052064.1\|UniProtKB=A0A0M6L0P8	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000049869.1\|UniProtKB=E1BC34	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000006761.6\|UniProtKB=F1MYF0	Bos taurus	O
BOVIN\|Gene=PRP4\|UniProtKB=P18917	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000025314.5\|UniProtKB=Q2WGK0	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000036106.4\|UniProtKB=Q2WG99	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000025304.5\|UniProtKB=Q2WFM8	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000025302.5\|UniProtKB=Q2PEE7	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000038718.3\|UniProtKB=A0A0M6L0Q6	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000051382.1\|UniProtKB=A0A3Q1M6B7	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000049075.1\|UniProtKB=A4PBQ6	Bos taurus	O
BOVIN\|Gene=CSH2\|UniProtKB=P19159	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000015274\|UniProtKB=P01239	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000039721.3\|UniProtKB=A0A286ZMS9	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00005013825\|UniProtKB=P01238	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000000114.4\|UniProtKB=A0A9L0SHR2	Equus caballus	O
HORSE\|Gene=PRL\|UniProtKB=P12420	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000015035\|UniProtKB=P46403	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845017595.1\|UniProtKB=E2RAF4	Canis lupus familiaris	O
MONDO\|Gene=PRL\|UniProtKB=O62819	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000011350.1\|UniProtKB=F6W2N8	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000011127.4\|UniProtKB=F7DGX1	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010008082\|UniProtKB=P14676	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000002939.3\|UniProtKB=G1KBD7	Anolis carolinensis	O
XENLA\|Gene=prl.2.S\|UniProtKB=A0A8J0TBC1	Xenopus laevis	O
XENLA\|Gene=LOC108695906\|UniProtKB=A0A8J0T9Y6	Xenopus laevis	O
XENTR\|Gene=LOC100498019\|UniProtKB=A0A8J1JWY0	Xenopus tropicalis	O
XENTR\|Gene=LOC100497196\|UniProtKB=A0A8J1K137	Xenopus tropicalis	O
XENTR\|Ensembl=ENSXETG00000035107\|UniProtKB=A0A6I8RB89	Xenopus tropicalis	O
XENLA\|Gene=prl.1.S\|UniProtKB=Q56A64	Xenopus laevis	O
XENLA\|Gene=prl.1.L\|UniProtKB=Q6DJG3	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-482866\|UniProtKB=A4QNQ2	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000016928.2\|UniProtKB=H2MR01	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030513-1\|UniProtKB=Q569P7	Danio rerio	O