PANTHER Gene Information

Gene Symbol(s):

20203443

Organism:

helobdella robusta

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Gene Name:

Guanylate cyclase domain-containing protein

Gene ID:

HelroG171005

Protein ID:

T1F3P4

Persistent Id:

PTN002899556

Alternate Ids:

HelroT171005(Ensembl_TRS)	XP_009015065(refSeq)
AMQM01003739(EMBL)	T1F3P4(Synonym)
HelroG171005(Ensembl)	ESO06969(EMBL-CDS)
HelroP171005(Ensembl_PRO)	675859010(GI)
T1F3P4_HELRO(UniProtKB-ID)	20203443(GeneID)
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PANTHER Classification

PANTHER Family:	ADENYLATE CYCLASE TYPE 1 (PTHR45627)
PANTHER Subfamily:	ADENYLATE CYCLASE TYPE 8 (PTHR45627:SF1)
PANTHER GO-slim Molecular Function:	adenylate cyclase activity
PANTHER GO-slim Biological Process:	purine ribonucleotide biosynthetic process adenylate cyclase-activating G protein-coupled receptor signaling pathway cyclic nucleotide metabolic process
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	adenylate cyclase

Pathway Categories:

Endothelin signaling pathway

Adenylate cyclase

GABA-B receptor II signaling

adenylate cyclase

Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway

Adenylyl cyclase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ATP binding, metal ion binding, lyase activity, adenylate cyclase activity
GO BP Complete:	cAMP biosynthetic process, adenylate cyclase-activating G protein-coupled receptor signaling pathway, cyclic nucleotide biosynthetic process, intracellular signal transduction
GO CC Complete:	membrane, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=239\|UniProtKB=P40145	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000020589.6\|UniProtKB=A0A2I3SK46	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015786.3\|UniProtKB=A0A2I2ZTJ4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000010440.4\|UniProtKB=A0A1D5Q874	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1341110\|UniProtKB=P97490	Mus musculus	LDO
RAT\|RGD=2036\|UniProtKB=P40146	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000014600.6\|UniProtKB=E1BQ12	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000031717.3\|UniProtKB=A0A287AWF4	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000024601.4\|UniProtKB=F6R859	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000006436.6\|UniProtKB=M3W5W8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845013615.1\|UniProtKB=A0A8I3NFX0	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000001430.4\|UniProtKB=F7BCI5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000008103.4\|UniProtKB=F7FY04	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010007962.1\|UniProtKB=A0A1D5PNE8	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000010598.4\|UniProtKB=G1KKD9	Anolis carolinensis	LDO
XENLA\|Gene=adcy8.S\|UniProtKB=A0A1L8FTY2	Xenopus laevis	O
XENLA\|Gene=adcy8.L\|UniProtKB=A0A1L8G048	Xenopus laevis	LDO
XENTR\|Ensembl=ENSXETG00000036330\|UniProtKB=A0A6I8SFS5	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000013598.2\|UniProtKB=H2MEQ6	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-041014-154\|UniProtKB=Q5RHR2	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-130530-619\|UniProtKB=E7FC63	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000016676.1\|UniProtKB=W5NIZ6	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000006410.2\|UniProtKB=A0A3B3HKU1	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-070912-197\|UniProtKB=B7UCF8	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000012663.1\|UniProtKB=W5N4M7	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000000490.3\|UniProtKB=F6YCG7	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118405038\|UniProtKB=A0A9J7HJ10	Branchiostoma floridae	LDO
DROME\|FlyBase=FBgn0024150\|UniProtKB=Q9VP76	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP002262\|UniProtKB=A0A1S4GF11	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC013722\|UniProtKB=A0A139WI81	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_318338\|UniProtKB=E9GII3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_247897\|UniProtKB=E9GT35	Daphnia pulex	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g234384\|UniProtKB=A7RRQ7	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG21914\|UniProtKB=B3RQI4	Trichoplax adhaerens	O
BATDJ\|Gene_ORFName=BATDEDRAFT_23648\|UniProtKB=F4NXY1	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0281545\|UniProtKB=Q03100	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_51614\|UniProtKB=F1A4L3	Dictyostelium purpureum	O
GIAIC\|EnsemblGenome=GL50803_16599\|UniProtKB=A8B947	Giardia intestinalis	O
PARTE\|EnsemblGenome=GSPATT00035944001\|UniProtKB=A0C7P7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028571001\|UniProtKB=A0BG69	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00020771001\|UniProtKB=A0DVQ1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00017090001\|UniProtKB=A0DI52	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00008342001\|UniProtKB=A0CM46	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00035991001\|UniProtKB=A0C7U3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00035327001\|UniProtKB=A0C5Y1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000356001\|UniProtKB=A0BBK4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00037686001\|UniProtKB=A0CEN0	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00037840001\|UniProtKB=A0CF34	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028233001\|UniProtKB=A0BF81	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00022215001\|UniProtKB=A0E179	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00008067001\|UniProtKB=A0CL53	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00013081001\|UniProtKB=A0D3H6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00030444001\|UniProtKB=A0BMP1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00008009001\|UniProtKB=A0CKZ5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00035245001\|UniProtKB=A0C5P9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00036203001\|UniProtKB=A0C8F3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00019986001\|UniProtKB=A0DTD8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00017694001\|UniProtKB=A0DJY3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00021918001\|UniProtKB=A0E0D3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000775001\|UniProtKB=A0CJU6	Paramecium tetraurelia	O
PARTE\|Gene_ORFName=PTMB.171c\|UniProtKB=Q6BG52	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00025644001\|UniProtKB=A0EC90	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00005251001\|UniProtKB=A0BPN4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00032566001\|UniProtKB=A0BVZ7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00030881001\|UniProtKB=A0BNX5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00025082001\|UniProtKB=A0EAN1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00029118001\|UniProtKB=A0BHR5	Paramecium tetraurelia	O